Ana Fernandez-Bustamante, MD
Associate Professor, Anesthesiology

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Medical Schools:
  • MD, University of Valladolid School of Medicine - Valladolid, Spain (1998)
  • PhD, Complutense University of Madrid (Spain) (2004)
Residency:
  • Complutense University of  Madrid - Madrid, Spain, Critical Care Medicine (2003)
Fellowships:
  • Johns Hopkins University Program, Adult Cardiothoracic Anesthesiology (2008)
Languages: English, Spanish
Department: Anesthesiology

Research Interests

Mechanical ventilation, lung inflammation, Acute Respiratory Distress Syndrome (ARDS)

Publications

  • Douin DJ, Krause M, Williams C, Tanabe K, Fernandez-Bustamante A, Quaye AN, Ginde AA, Bartels K. Corticosteroid Administration and Impaired Glycemic Control in Mechanically Ventilated COVID-19 Patients. Semin Cardiothorac Vasc Anesth. 2021 Sep 2;:10892532211043313. [Epub ahead of print] PubMed PMID: 34470529
  • Selby LV, Fernandez-Bustamante A, Ejaz A, Gleisner A, Pawlik TM, Douin DJ. Association Between Anesthesia Delivered During Tumor Resection and Cancer Survival: a Systematic Review of a Mixed Picture with Constant Themes. J Gastrointest Surg. 2021 Aug;25(8):2129-2141. PubMed PMID: 34100251
  • Fernandez-Bustamante A, Sprung J. Intraoperative Positive End-expiratory Pressure for Obese Patients: A Step Forward, a Long Road Still Ahead. Anesthesiology. 2021 Jun 1;134(6):838-840. PubMed PMID: 33909874
  • Krause M, Douin DJ, Kim KK, Fernandez-Bustamante A, Bartels K. Characteristics and Outcomes of Mechanically Ventilated COVID-19 Patients-An Observational Cohort Study. J Intensive Care Med. 2021 Mar;36(3):271-276. PubMed PMID: 32873103
  • Krause M, Douin DJ, Tran TT, Fernandez-Bustamante A, Aftab M, Bartels K. Association between procalcitonin levels and duration of mechanical ventilation in COVID-19 patients. PLoS One. 2020;15(9):e0239174. PubMed PMID: 32946466
  • Krause M, Douin DJ, Kim KK, Fernandez-Bustamante A, Bartels K. Characteristics and Outcomes of Mechanically Ventilated COVID-19 Patients-An Observational Cohort Study. J Intensive Care Med. 2020 Sep 2;:885066620954806. [Epub ahead of print] PubMed PMID: 32873103
  • Fernandez-Bustamante A, Sprung J, Parker RA, Bartels K, Weingarten TN, Kosour C, Thompson BT, Vidal Melo MF. Individualized PEEP to optimise respiratory mechanics during abdominal surgery: a pilot randomised controlled trial. Br J Anaesth. 2020 Sep;125(3):383-392. PubMed PMID: 32682559
  • Repine KM, Hendrickse A, Tran TT, Bartels K, Fernandez-Bustamante A. Opioid-Free Epidural-Free Anesthesia for Open Hepatectomy: A Case Report. A A Pract. 2020 Jun;14(8):e01238. PubMed PMID: 32643901
  • Abrams BA, Murray KA, Mahoney K, Raymond KM, McWilliams SK, Nichols S, Mahmoudi E, Mayes LM, Fernandez-Bustamante A, Mitchell JD, Meguid RA, Zanotti G, Bartels K. Post-Discharge Pain Management After Thoracic Surgery - A Patient-Centered Approach. Ann Thorac Surg. 2020 Jun 1. [Epub ahead of print] PubMed PMID: 32497643
  • Krause M, Fernandez-Bustamante A, Bartels K. In Response. Anesth Analg. 2020 Mar 16. [Epub ahead of print] PubMed PMID: 32243290
  • Bartels K, Kaizer A, Jameson L, Bullard K, Dingmann C, Fernandez-Bustamante A. Hypoxemia Within the First 3 Postoperative Days Is Associated With Increased 1-Year Postoperative Mortality After Adjusting for Perioperative Opioids and Other Confounders. Anesth Analg. 2020 Aug;131(2):555-563. PubMed PMID: 31971921
  • Gerard SE, Herrmann J, Kaczka DW, Musch G, Fernandez-Bustamante A, Reinhardt JM. Multi-resolution convolutional neural networks for fully automated segmentation of acutely injured lungs in multiple species. Med Image Anal. 2020 Feb;60:101592. PubMed PMID: 31760194
  • Krause M, McWilliams SK, Bullard KJ, Mayes LM, Jameson LC, Mikulich-Gilbertson SK, Fernandez-Bustamante A, Bartels K. Neostigmine Versus Sugammadex for Reversal of Neuromuscular Blockade and Effects on Reintubation for Respiratory Failure or Newly Initiated Noninvasive Ventilation: An Interrupted Time Series Design. Anesth Analg. 2020 Jul;131(1):141-151. PubMed PMID: 31702700
  • Bartels K, Mahoney K, Raymond KM, McWilliams SK, Fernandez-Bustamante A, Schulick R, Hopfer CJ, Mikulich-Gilbertson SK. Opioid and non-opioid utilization at home following gastrointestinal procedures: a prospective cohort study. Surg Endosc. 2020 Jan;34(1):304-311. PubMed PMID: 30945059
  • Krause M, Fernandez-Bustamante A, Bartels K. In Response. Anesth Analg. 2020 Aug;131(2):e79-e80. PubMed PMID: 33031673
  • Abrams BA, Murray KA, Mahoney K, Raymond KM, McWilliams SK, Nichols S, Mahmoudi E, Mayes LM, Fernandez-Bustamante A, Mitchell JD, Meguid RA, Zanotti G, Bartels K. Postdischarge Pain Management After Thoracic Surgery: A Patient-Centered Approach. Ann Thorac Surg. 2020 Nov;110(5):1714-1721. PubMed PMID: 32497643
  • Bartels K, Mahoney K, Raymond KM, McWilliams SK, Fernandez-Bustamante A, Schulick R, Hopfer CJ, Mikulich-Gilbertson SK. Opioid and non-opioid utilization at home following gastrointestinal procedures: a prospective cohort study. Surg Endosc. 2019 Apr 3. [Epub ahead of print] PubMed PMID: 30945059
  • Bluth T, Serpa Neto A, Schultz MJ, Pelosi P, Gama de Abreu M. Effect of Intraoperative High Positive End-Expiratory Pressure (PEEP) With Recruitment Maneuvers vs Low PEEP on Postoperative Pulmonary Complications in Obese Patients: A Randomized Clinical Trial. JAMA. 2019 Jun 18;321(23):2292-2305. PubMed PMID: 31157366
  • Fernandez-Bustamante A, Vidal Melo MF. Bedside assessment of lung aeration and stretch. Br J Anaesth. 2018 Nov;121(5):1001-1004. PubMed PMID: 30336843
  • Mayes LM, Wong CA, Zimmer S, Fernandez-Bustamante A, Bartels K. Gender differences in career development awards in United States' anesthesiology and surgery departments, 2006-2016. BMC Anesthesiol. 2018 Jul 27;18(1):95. PubMed PMID: 30049265
  • Merkow JS, Hoerauf JM, Moss AF, Brainard J, Mayes LM, Fernandez-Bustamante A, Mikulich-Gilbertson SK, Bartels K. Animal experimental research design in critical care. BMC Med Res Methodol. 2018 Jul 5;18(1):71. PubMed PMID: 29976162
  • Bartels K, Fernandez-Bustamante A, McWilliams SK, Hopfer CJ, Mikulich-Gilbertson SK. Long-term opioid use after inpatient surgery - A retrospective cohort study. Drug Alcohol Depend. 2018 Jun 1;187:61-65. PubMed PMID: 29627407
  • Serpa Neto A, Juffermans NP, Hemmes SNT, Barbas CSV, Beiderlinden M, Biehl M, Fernandez-Bustamante A, Futier E, Gajic O, Jaber S, Kozian A, Licker M, Lin WQ, Memtsoudis SG, Miranda DR, Moine P, Paparella D, Ranieri M, Scavonetto F, Schilling T, Selmo G, Severgnini P, Sprung J, Sundar S, Talmor D, Treschan T, Unzueta C, Weingarten TN, Wolthuis EK, Wrigge H, de Abreu MG, Pelosi P, Schultz MJ. Interaction between peri-operative blood transfusion, tidal volume, airway pressure and postoperative ARDS: an individual patient data meta-analysis. Ann Transl Med. 2018 Jan;6(2):23. PubMed PMID: 29430440
  • Shah CK, Moss A, Henderson W, Sullivan B, Fernandez-Bustamante A. Quick reference tidal volume cards reduce the incidence of large tidal volumes during surgery. J Anesth. 2018 Feb;32(1):137-142. PubMed PMID: 29134425
  • Fernandez-Bustamante A, Vidal Melo MF. Bedside assessment of lung aeration and stretch. Br J Anaesth. 2018 Nov;121(5):1001-1004. PubMed PMID: 30336843
  • Fernandez-Bustamante A, Schoen J, Vidal Melo MF. Incentive Spirometry After Bariatric Surgery: The Importance of Patient Compliance. JAMA Surg. 2017 Oct 1;152(10):984-985. PubMed PMID: 28636722
  • Fernandez-Bustamante A, Vidal Melo MF. The Increasing Call for Protective Ventilation During Anesthesia-Reply. JAMA Surg. 2017 Sep 1;152(9):894. PubMed PMID: 28593302
  • Brainard J, Scott BK, Sullivan BL, Fernandez-Bustamante A, Piccoli JR, Gebbink MG, Bartels K. Heated humidified high-flow nasal cannula oxygen after thoracic surgery - A randomized prospective clinical pilot trial. J Crit Care. 2017 Aug;40:225-228. PubMed PMID: 28454060
  • Bender SP, Paganelli WC, Gerety LP, Tharp WG, Shanks AM, Housey M, Blank RS, Colquhoun DA, Fernandez-Bustamante A, Jameson LC, Kheterpal S. Intraoperative Lung-Protective Ventilation Trends and Practice Patterns: A Report from the Multicenter Perioperative Outcomes Group. Anesth Analg. 2015 Nov;121(5):1231-9. PubMed PMID: 26332856
  • Fernandez-Bustamante A, Agazio A, Wilson P, Elkins N, Domaleski L, He Q, Baer KA, Moss AF, Wischmeyer PE, Repine JE. Brief Glutamine Pretreatment Increases Alveolar Macrophage CD163/Heme Oxygenase-1/p38-MAPK Dephosphorylation Pathway and Decreases Capillary Damage but Not Neutrophil Recruitment in IL-1/LPS-Insufflated Rats. PLoS One. 2015;10(7):e0130764. PubMed PMID: 26147379
  • Bartels K, Babu AN, Fernandez-Bustamante A. Subtle but serious: Pulmonary support after cardiac surgery. J Crit Care. 2015 Jun 11. [Epub ahead of print] PubMed PMID: 26117218
  • Fernandez-Bustamante A, Seres T. In reply. Anesthesiology. 2015 May;122(5):1181. PubMed PMID: 25985029
  • Serpa Neto A, Hemmes SN, Barbas CS, Beiderlinden M, Biehl M, Binnekade JM, Canet J, Fernandez-Bustamante A, Futier E, Gajic O, Hedenstierna G, Hollmann MW, Jaber S, Kozian A, Licker M, Lin WQ, Maslow AD, Memtsoudis SG, Reis Miranda D, Moine P, Ng T, Paparella D, Putensen C, Ranieri M, Scavonetto F, Schilling T, Schmid W, Selmo G, Severgnini P, Sprung J, Sundar S, Talmor D, Treschan T, Unzueta C, Weingarten TN, Wolthuis EK, Wrigge H, Gama de Abreu M, Pelosi P, Schultz MJ. Protective versus Conventional Ventilation for Surgery: A Systematic Review and Individual Patient Data Meta-analysis. Anesthesiology. 2015 Jul;123(1):66-78. PubMed PMID: 25978326
  • Fernandez-Bustamante A, Hashimoto S, Serpa Neto A, Moine P, Vidal Melo MF, Repine JE. Perioperative lung protective ventilation in obese patients. BMC Anesthesiol. 2015 May 6;15:56. PubMed PMID: 25907273
  • Wanderer JP, Ehrenfeld JM, Epstein RH, Kor DJ, Bartz RR, Fernandez-Bustamante A, Vidal Melo MF, Blum JM. Temporal trends and current practice patterns for intraoperative ventilation at U.S. academic medical centers: a retrospective study. BMC Anesthesiol. 2015;15:40. PubMed PMID: 25852301
  • Serpa Neto A, Hemmes SN, Barbas CS, Beiderlinden M, Fernandez-Bustamante A, Futier E, Hollmann MW, Jaber S, Kozian A, Licker M, Lin WQ, Moine P, Scavonetto F, Schilling T, Selmo G, Severgnini P, Sprung J, Treschan T, Unzueta C, Weingarten TN, Wolthuis EK, Wrigge H, Gama de Abreu M, Pelosi P, Schultz MJ, PROVE Network investigators. Incidence of mortality and morbidity related to postoperative lung injury in patients who have undergone abdominal or thoracic surgery: a systematic review and meta-analysis. Lancet Respir Med. 2014 Dec;2(12):1007-15. PubMed PMID: 25466352
  • Mehta N, Fernandez-Bustamante A, Seres T. A review of intraoperative goal-directed therapy using arterial waveform analysis for assessment of cardiac output. ScientificWorldJournal. 2014;2014:702964. PubMed PMID: 24987744
  • Fernandez-Bustamante A, Klawitter J, Repine JE, Agazio A, Janocha AJ, Shah C, Moss M, Douglas IS, Tran ZV, Erzurum SC, Christians U, Seres T. Early effect of tidal volume on lung injury biomarkers in surgical patients with healthy lungs. Anesthesiology. 2014 Sep;121(3):469-81. PubMed PMID: 24809976
  • Fernandez-Bustamante A, Repine JE. Chronic inflammatory diseases and the Acute Respiratory Distress Syndrome (ARDS). Curr Pharm Des. 2014;20(9):1400-8. PubMed PMID: 23978096
  • Serpa Neto A, Hemmes SN, Barbas CS, Beiderlinden M, Fernandez-Bustamante A, Futier E, Hollmann MW, Jaber S, Kozian A, Licker M, Lin WQ, Moine P, Scavonetto F, Schilling T, Selmo G, Severgnini P, Sprung J, Treschan T, Unzueta C, Weingarten TN, Wolthuis EK, Wrigge H, Gama de Abreu M, Pelosi P, Schultz MJ. Incidence of mortality and morbidity related to postoperative lung injury in patients who have undergone abdominal or thoracic surgery: a systematic review and meta-analysis. Lancet Respir Med. 2014 Dec;2(12):1007-15. PubMed PMID: 25466352
  • Kheterpal S, Healy D, Aziz MF, Shanks AM, Freundlich RE, Linton F, Martin LD, Linton J, Epps JL, Fernandez-Bustamante A, Jameson LC, Tremper T, Tremper KK, Multicenter Perioperative Outcomes Group (MPOG) Perioperative Clinical Research Committee. Incidence, predictors, and outcome of difficult mask ventilation combined with difficult laryngoscopy: a report from the multicenter perioperative outcomes group. Anesthesiology. 2013 Dec;119(6):1360-9. PubMed PMID: 24071617
  • Fernandez-Bustamante A, Klawitter J, Wilson P, Elkins ND, Agazio A, Shibata T, Uchida K, Christians U, Repine JE. Early increase in alveolar macrophage prostaglandin 15d-PGJ2 precedes neutrophil recruitment into lungs of cytokine-insufflated rats. Inflammation. 2013 Oct;36(5):1030-40. PubMed PMID: 23616184
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Practice Locations

University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

Hospital Affiliation
  • University of Colorado Hospital

Specialty Information

Specialties
  • Anesthesiology (2003, 2015)
Clinical Interests
Mechanical ventilation, intraoperative jet ventilation, postoperative outcomes, thoracic/airway anesthesia, bariatric anesthesia.

General Information

Medical Schools:
  • MD, University of Valladolid School of Medicine - Valladolid, Spain (1998)
  • PhD, Complutense University of Madrid (Spain) (2004)
Residency Programs:
  • Complutense University of  Madrid - Madrid, Spain, Critical Care Medicine (2003)
Fellowships:
  • Johns Hopkins University Program, Adult Cardiothoracic Anesthesiology (2008)
Languages: English, Spanish
Department: Anesthesiology
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