Richard Tobin, PhD
Assistant Research Professor, Surgery-Surgical Oncology

Publications

• Katsnelson EN, Spengler A, Domenico J, Couts KL, Loh L, Gapin L, McCarter MD, Tobin RP. Dysfunctional States of Unconventional T cell Subsets in Cancer. J Leukoc Biol. 2023 Oct 14. [Epub ahead of print] PubMed PMID: 37837379
• Palmer WH, Leaton LA, Campos Codo A, Crute B, Roest J, Zhu S, Petersen J, Tobin RP, Hume PS, Stone M, van Bokhoven A, Gerich ME, McCarter MD, Zhu Y, Janssen WJ, Vivian JP, Trowsdale J, Getahun A, Rossjohn J, Cambier J, Loh L, Norman PJ. Polymorphic KIR3DL3 expression modulates tissue-resident and innate-like T cells. Sci Immunol. 2023 Jun 30;8(84):eade5343. PubMed PMID: 37390222
• Turner JA, Fredrickson MA, D'Antonio M, Katsnelson E, MacBeth M, Van Gulick R, Chimed TS, McCarter M, D'Alessandro A, Robinson WA, Couts KL, Pelanda R, Klarquist J, Tobin RP, Torres RM. Lysophosphatidic acid modulates CD8 T cell immunosurveillance and metabolism to impair anti-tumor immunity. Nat Commun. 2023 Jun 3;14(1):3214. PubMed PMID: 37270644
• Tobin RP, Cogswell DT, Cates VM, Davis DM, Borgers JSW, Van Gulick RJ, Katsnelson E, Couts KL, Jordan KR, Gao D, Davila E, Medina TM, Lewis KD, Gonzalez R, McFarland RW, Robinson WA, McCarter MD. Targeting MDSC Differentiation Using ATRA: A Phase I/II Clinical Trial Combining Pembrolizumab and All-Trans Retinoic Acid for Metastatic Melanoma. Clin Cancer Res. 2023 Apr 3;29(7):1209-1219. PubMed PMID: 36378549
• Tobin RP, Cogswell DT, Cates VM, Davis DM, Borgers JSW, Van Gulick RJ, Katsnelson E, Couts KL, Jordan KR, Gao D, Davila E, Medina TM, Lewis KD, Gonzalez R, McFarland RW, Robinson WA, McCarter MD. Targeting MDSC differentiation using ATRA: a phase I/II clinical trial combining pembrolizumab and all-trans retinoic acid for metastatic melanoma. Clin Cancer Res. 2022 Nov 15. [Epub ahead of print] PubMed PMID: 36378549
• Newell-Rogers MK, Duong A, Nazarali R, Tobin RP, Rogers SK, Shapiro LA. Unilateral Cervical Vagotomy Modulates Immune Cell Profiles and the Response to a Traumatic Brain Injury. Int J Mol Sci. 2022 Aug 30;23(17). PubMed PMID: 36077246
• Turner JA, Paton EL, Van Gulick R, Stefanoni D, Cendali F, Reisz J, Tobin RP, McCarter M, D'Alessandro A, Torres RM, Robinson WA, Couts KL, Schlaepfer IR. BRAF Modulates Lipid Use and Accumulation. Cancers (Basel). 2022 Apr 23;14(9). PubMed PMID: 35565240
• Vorwald VM, Davis DM, Van Gulick RJ, Torphy RJ, Borgers JS, Klarquist J, Couts KL, Amato CM, Cogswell DT, Fujita M, Castleman MJ, Davis T, Lozupone C, Medina TM, Robinson WA, Gapin L, McCarter MD, Tobin RP. Circulating CD8( ) mucosal-associated invariant T cells correlate with improved treatment responses and overall survival in anti-PD-1-treated melanoma patients. Clin Transl Immunology. 2022;11(1):e1367. PubMed PMID: 35028137
• Mukherjee N, Dart CR, Amato CM, Honig-Frand A, Lambert JR, Lambert KA, Robinson WA, Tobin RP, McCarter MD, Couts KL, Fujita M, Norris DA, Shellman YG. Expression Differences in BCL2 Family Members between Uveal and Cutaneous Melanomas Account for Varying Sensitivity to BH3 Mimetics. J Invest Dermatol. 2022 Jul;142(7):1912-1922.e7. PubMed PMID: 34942200
• Mukherjee N, Dart CR, Amato CM, Honig-Frand A, Lambert JR, Lambert KA, Robinson WA, Tobin RP, McCarter MD, Couts KL, Fujita M, Norris DA, Shellman YG. Expression differences in BCL2 family members between uveal and cutaneous melanomas account for varying sensitivity to BH3 mimetics. J Invest Dermatol. 2021 Dec 20. [Epub ahead of print] PubMed PMID: 34942200
• Borgers JSW, Tobin RP, Torphy RJ, Vorwald VM, Van Gulick RJ, Amato CM, Cogswell DT, Chimed TS, Couts KL, Van Bokhoven A, Raeburn CD, Lewis KD, Wisell J, McCarter MD, Mushtaq RR, Robinson WA. Melanoma Metastases to the Adrenal Gland Are Highly Resistant to Immune Checkpoint Inhibitors. J Natl Compr Canc Netw. 2021 Aug 4. [Epub ahead of print] PubMed PMID: 34348236
• Cogswell DT, Gapin L, Tobin HM, McCarter MD, Tobin RP. MAIT Cells: Partners or Enemies in Cancer Immunotherapy?. Cancers (Basel). 2021 Mar 25;13(7). PubMed PMID: 33805904
• Vorwald, V.M., Davis, D.M., Van Gulick, R.J., Torphy, R.J., Borgers, J.S., Klarquist, J., Couts, K.L., Amato, C.M., Cogswell, D.T., Fujita, M., Castleman, M.J., Davis, T., Lozupone, C., Medina, T.M., Robinson, W.A., Gapin, L., McCarter, M.D. and Tobin, R.P. (2022), Circulating CD8+ mucosal-associated invariant T cells correlate with improved treatment responses and overall survival in anti-PD-1-treated melanoma patients. Clin Transl Immunol, 11: e1367. https://doi.org/10.1002/cti2.1367
• Turner, Jacqueline A.; Van Gulick, Robert; Robinson, William A.; Mughal, Tariq; Tobin, Richard P.; MacBeth, Morgan L.; Classon, Anthony; Bagby, Stacey M.; Yacob, Betelehem W.; Hartman, Sarah J.; Silverman, Ian; Vorwald, Victoria M.; Holman, Blair; Gorden, Nicholas; Gonzalez, Rita; Gay, Laurie M.; Ali, Siraj M.; Benson, Adam; Miller, Vincent A.; Ross, Jeffrey S.; Pitts, Todd M.; Rioth, Matthew J.; Lewis, Karl D.; Medina, Theresa; McCarter, Martin D.; Gonzalez, Rene; Couts, Kasey. Expanding the landscape of oncogenic drivers and treatment options in acral and mucosal melanomas by targeted genomic profiling. International Journal of Cancer. In-Press.