Edward Melanson, PhD, FACSM
Professor, Medicine-Endocrinology/Metabolism/Diabetes

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Graduate Schools :
  • PhD, University of Massachusetts Amherst (1999)
  • MS, University of Massachusetts Amherst (1994)
Languages: English
Department: Medicine-Endocrinology/Metabolism/Diabetes

Publications

  • Depner CM, Cogswell DT, Bisesi PJ, Markwald RR, Cruickshank-Quinn C, Quinn K, Melanson EL, Reisdorph N, Wright KP Jr. Developing preliminary blood metabolomics-based biomarkers of insufficient sleep in humans. Sleep. 2020 Jan 2. [Epub ahead of print] PubMed PMID: 31894238
  • Willis EA, Creasy SA, Honas JJ, Melanson EL, Donnelly JE. The effects of exercise session timing on weight loss and components of energy balance: midwest exercise trial 2. Int J Obes (Lond). 2020 Jan;44(1):114-124. PubMed PMID: 31289334
  • Giles ED, Brown IL, MacLean PS, Pan Z, Melanson EL, Heard KJ, Cornier MA, Marden T, Higgins JA. The In Vivo Net Energy Content of Resistant Starch and Its Effect on Macronutrient Oxidation in Healthy Adults. Nutrients. 2019 Oct 16;11(10). PubMed PMID: 31623184
  • Rynders CA, Thomas EA, Zaman A, Pan Z, Catenacci VA, Melanson EL. Effectiveness of Intermittent Fasting and Time-Restricted Feeding Compared to Continuous Energy Restriction for Weight Loss. Nutrients. 2019 Oct 14;11(10). PubMed PMID: 31614992
  • Catenacci VA, Ostendorf DM, Pan Z, Bing K, Wayland LT, Seyoum E, Stauffer BL, Phelan S, Creasy SA, Caldwell AE, Wyatt HR, Bessesen DH, Melanson EL. The Impact of Timing of Exercise Initiation on Weight Loss: An 18-Month Randomized Clinical Trial. Obesity (Silver Spring). 2019 Nov;27(11):1828-1838. PubMed PMID: 31565869
  • Berman ESF, Swibas T, Kohrt WM, Catenacci VA, Creasy SA, Melanson EL, Speakman JR. Maximizing precision and accuracy of the doubly labeled water method via optimal sampling protocol, calculation choices, and incorporation of (17)O measurements. Eur J Clin Nutr. 2019 Aug 19. [Epub ahead of print] PubMed PMID: 31427762
  • Kohrt WM, Wolfe P, Sherk VD, Wherry SJ, Wellington T, Melanson EL, Swanson CM, Weaver CM, Boxer RS. Dermal Calcium Loss Is Not the Primary Determinant of Parathyroid Hormone Secretion during Exercise. Med Sci Sports Exerc. 2019 Oct;51(10):2117-2124. PubMed PMID: 31009423
  • Creasy SA, Crane TE, Garcia DO, Thomson CA, Kohler LN, Wertheim BC, Baker LD, Coday M, Hale L, Womack CR, Wright KP, Melanson EL. Higher amounts of sedentary time are associated with short sleep duration and poor sleep quality in postmenopausal women. Sleep. 2019 Jul 8;42(7). PubMed PMID: 30994175
  • Presby DM, Jackman MR, Rudolph MC, Sherk VD, Foright RM, Houck JA, Johnson GC, Orlicky DJ, Melanson EL, Higgins JA, MacLean PS. Compensation for cold-induced thermogenesis during weight loss maintenance and regain. Am J Physiol Endocrinol Metab. 2019 May 1;316(5):E977-E986. PubMed PMID: 30912962
  • Depner CM, Melanson EL, Eckel RH, Snell-Bergeon JK, Perreault L, Bergman BC, Higgins JA, Guerin MK, Stothard ER, Morton SJ, Wright KP Jr. Ad libitum Weekend Recovery Sleep Fails to Prevent Metabolic Dysregulation during a Repeating Pattern of Insufficient Sleep and Weekend Recovery Sleep. Curr Biol. 2019 Mar 18;29(6):957-967.e4. PubMed PMID: 30827911
  • Ostendorf DM, Caldwell AE, Creasy SA, Pan Z, Lyden K, Bergouignan A, MacLean PS, Wyatt HR, Hill JO, Melanson EL, Catenacci VA. Physical Activity Energy Expenditure and Total Daily Energy Expenditure in Successful Weight Loss Maintainers. Obesity (Silver Spring). 2019 Mar;27(3):496-504. PubMed PMID: 30801984
  • De Jong NP, Rynders CA, Goldstrohm DA, Pan Z, Lange AH, Mendez C, Melanson EL, Bessesen DH, Bergouignan A. Effect of frequent interruptions of sedentary time on nutrient metabolism in sedentary overweight male and female adults. J Appl Physiol (1985). 2019 Apr 1;126(4):984-992. PubMed PMID: 30629473
  • Kline PW, Melanson EL, Sullivan WJ, Blatchford PJ, Miller MJ, Stevens-Lapsley JE, Christiansen CL. Improving Physical Activity Through Adjunct Telerehabilitation Following Total Knee Arthroplasty: Randomized Controlled Trial Protocol. Phys Ther. 2019 Jan 1;99(1):37-45. PubMed PMID: 30329126
  • Schenkman M, Moore CG, Kohrt WM, Hall DA, Delitto A, Comella CL, Josbeno DA, Christiansen CL, Berman BD, Kluger BM, Melanson EL, Jain S, Robichaud JA, Poon C, Corcos DM. Effect of High-Intensity Treadmill Exercise on Motor Symptoms in Patients With De Novo Parkinson Disease: A Phase 2 Randomized Clinical Trial. JAMA Neurol. 2018 Feb 1;75(2):219-226. PubMed PMID: 29228079
  • Ostendorf DM, Lyden K, Pan Z, Wyatt HR, Hill JO, Melanson EL, Catenacci VA. Objectively Measured Physical Activity and Sedentary Behavior in Successful Weight Loss Maintainers. Obesity (Silver Spring). 2018 Jan;26(1):53-60. PubMed PMID: 29090513
  • Melanson EL, Swibas T, Kohrt WM, Catenacci VA, Creasy SA, Plasqui G, Wouters L, Speakman JR, Berman ESF. Validation of the doubly labeled water method using off-axis integrated cavity output spectroscopy and isotope ratio mass spectrometry. Am J Physiol Endocrinol Metab. 2018 Feb 1;314(2):E124-E130. PubMed PMID: 28978547
  • Ostendorf DM, Melanson EL, Caldwell AE, Creasy SA, Pan Z, MacLean PS, Wyatt HR, Hill JO, Catenacci VA. No consistent evidence of a disproportionately low resting energy expenditure in long-term successful weight-loss maintainers. Am J Clin Nutr. 2018 Oct 1;108(4):658-666. PubMed PMID: 30321282
  • Gavin KM, Kohrt WM, Klemm DJ, Melanson EL. Modulation of Energy Expenditure by Estrogens and Exercise in Women. Exerc Sport Sci Rev. 2018 Oct;46(4):232-239. PubMed PMID: 30001272
  • LaRoche DP, Melanson EL, Baumgartner MP, Bozzuto BM, Libby VM, Marshall BN. Physiological determinants of walking effort in older adults: should they be targets for physical activity intervention?. Geroscience. 2018 Jun;40(3):305-315. PubMed PMID: 29961239
  • Melanson EL, Ritchie HK, Dear TB, Catenacci V, Shea K, Connick E, Moehlman TM, Stothard ER, Higgins J, McHill AW, Wright KP Jr. Daytime bright light exposure, metabolism, and individual differences in wake and sleep energy expenditure during circadian entrainment and misalignment. Neurobiol Sleep Circadian Rhythms. 2018 Jan;4:49-56. PubMed PMID: 29876528
  • Depner CM, Melanson EL, McHill AW, Wright KP Jr. Mistimed food intake and sleep alters 24-hour time-of-day patterns of the human plasma proteome. Proc Natl Acad Sci U S A. 2018 Jun 5;115(23):E5390-E5399. PubMed PMID: 29784788
  • Kaviani S, Schoeller DA, Ravussin E, Melanson EL, Henes ST, Dugas LR, Dechert RE, Mitri G, Schoffelen PFM, Gubbels P, Tornberg A, Garland S, Akkermans M, Cooper JA. Determining the Accuracy and Reliability of Indirect Calorimeters Utilizing the Methanol Combustion Technique. Nutr Clin Pract. 2018 Apr;33(2):206-216. PubMed PMID: 29658183
  • Melanson EL, Lyden K, Gibbons E, Gavin KM, Wolfe P, Wierman ME, Schwartz RS, Kohrt WM. Influence of Estradiol Status on Physical Activity in Premenopausal Women. Med Sci Sports Exerc. 2018 Aug;50(8):1704-1709. PubMed PMID: 29509642
  • Schenkman M, Moore CG, Kohrt WM, Hall DA, Delitto A, Comella CL, Josbeno DA, Christiansen CL, Berman BD, Kluger BM, Melanson EL, Jain S, Robichaud JA, Poon C, Corcos DM. Effect of High-Intensity Treadmill Exercise on Motor Symptoms in Patients With De Novo Parkinson Disease: A Phase 2 Randomized Clinical Trial. JAMA Neurol. 2018 Feb 1;75(2):219-226. PubMed PMID: 29228079
  • Ostendorf DM, Lyden K, Pan Z, Wyatt HR, Hill JO, Melanson EL, Catenacci VA. Objectively Measured Physical Activity and Sedentary Behavior in Successful Weight Loss Maintainers. Obesity (Silver Spring). 2018 Jan;26(1):53-60. PubMed PMID: 29090513
  • Melanson EL, Swibas T, Kohrt WM, Catenacci VA, Creasy SA, Plasqui G, Wouters L, Speakman JR, Berman ESF. Validation of the doubly labeled water method using off-axis integrated cavity output spectroscopy and isotope ratio mass spectrometry. Am J Physiol Endocrinol Metab. 2018 Feb 1;314(2):E124-E130. PubMed PMID: 28978547
  • Hegde N, Bries M, Swibas T, Melanson E, Sazonov E, Hegde N, Bries M, Swibas T, Melanson E, Sazonov E. Automatic Recognition of Activities of Daily Living Utilizing Insole-Based and Wrist-Worn Wearable Sensors. IEEE J Biomed Health Inform. 2018 Jul;22(4):979-988. PubMed PMID: 28783651
  • Hegde N, Bries M, Melanson E, Sazonov E. One size fits all electronics for insole-based activity monitoring. Conf Proc IEEE Eng Med Biol Soc. 2017 Jul;2017:3564-3567. PubMed PMID: 29060668
  • Hegde N, Bries M, Swibas T, Melanson E, Sazonov E. Automatic Recognition of Activities of Daily Living utilizing Insole Based and Wrist Worn Wearable Sensors. IEEE J Biomed Health Inform. 2017 Aug 1. [Epub ahead of print] PubMed PMID: 28783651
  • Christiansen C, Moore C, Schenkman M, Kluger B, Kohrt W, Delitto A, Berman B, Hall D, Josbeno D, Poon C, Robichaud J, Wellington T, Jain S, Comella C, Corcos D, Melanson E. Factors Associated With Ambulatory Activity in De Novo Parkinson Disease. J Neurol Phys Ther. 2017 Apr;41(2):93-100. PubMed PMID: 28263256
  • Melanson EL. The effect of exercise on non-exercise physical activity and sedentary behavior in adults. Obes Rev. 2017 Feb;18 Suppl 1:40-49. PubMed PMID: 28164451
  • Christiansen C, Moore C, Schenkman M, Kluger B, Kohrt W, Delitto A, Berman B, Hall D, Josbeno D, Poon C, Robichaud J, Wellington T, Jain S, Comella C, Corcos D, Melanson E. Factors Associated With Ambulatory Activity in De Novo Parkinson Disease. J Neurol Phys Ther. 2017 Apr;41(2):93-100. PubMed PMID: 28263256
  • Catenacci VA, Pan Z, Ostendorf D, Brannon S, Gozansky WS, Mattson MP, Martin B, MacLean PS, Melanson EL, Troy Donahoo W. A randomized pilot study comparing zero-calorie alternate-day fasting to daily caloric restriction in adults with obesity. Obesity (Silver Spring). 2016 Sep;24(9):1874-83. PubMed PMID: 27569118
  • Peterman JE, Wright KP Jr, Melanson EL, Kram R, Byrnes WC. Motor-Driven (Passive) Cycling: A Potential Physical Inactivity Countermeasure?. Med Sci Sports Exerc. 2016 Sep;48(9):1821-8. PubMed PMID: 27054677
  • Legget KT, Wylie KP, Cornier MA, Melanson EL, Paschall CJ, Tregellas JR. Exercise-related changes in between-network connectivity in overweight/obese adults. Physiol Behav. 2016 May 1;158:60-7. PubMed PMID: 26921099
  • Fontana JM, Higgins JA, Schuckers SC, Bellisle F, Pan Z, Melanson EL, Neuman MR, Sazonov E. Energy intake estimation from counts of chews and swallows. Appetite. 2015 Feb;85:14-21. PubMed PMID: 25447016
  • Eckel RH, Depner CM, Perreault L, Markwald RR, Smith MR, McHill AW, Higgins J, Melanson EL, Wright KP Jr. Morning Circadian Misalignment during Short Sleep Duration Impacts Insulin Sensitivity. Curr Biol. 2015 Nov 16;25(22):3004-10. PubMed PMID: 26549253
  • Paxton RJ, Melanson EL, Stevens-Lapsley JE, Christiansen CL. Physical activity after total knee arthroplasty: A critical review. World J Orthop. 2015 Sep 18;6(8):614-22. PubMed PMID: 26396937
  • Melanson EL, Gavin KM, Shea KL, Wolfe P, Wierman ME, Schwartz RS, Kohrt WM. Regulation of energy expenditure by estradiol in premenopausal women. J Appl Physiol (1985). 2015 Nov 1;119(9):975-81. PubMed PMID: 26338457
  • Sazonov E, Hegde N, Browning RC, Melanson EL, Sazonova NA. Posture and activity recognition and energy expenditure estimation in a wearable platform. IEEE J Biomed Health Inform. 2015 Jul;19(4):1339-46. PubMed PMID: 26011870
  • Berman ES, Melanson EL, Swibas T, Snaith SP, Speakman JR. Inter- and intraindividual correlations of background abundances of (2)H, (18)O and (17)O in human urine and implications for DLW measurements. Eur J Clin Nutr. 2015 Oct;69(10):1091-8. PubMed PMID: 25804273
  • Shea KL, Gavin KM, Melanson EL, Gibbons E, Stavros A, Wolfe P, Kittelson JM, Vondracek SF, Schwartz RS, Wierman ME, Kohrt WM. Body composition and bone mineral density after ovarian hormone suppression with or without estradiol treatment. Menopause. 2015 Oct;22(10):1045-52. PubMed PMID: 25783468
  • Fontana JM, Higgins JA, Schuckers SC, Bellisle F, Pan Z, Melanson EL, Neuman MR, Sazonov E. Energy intake estimation from counts of chews and swallows. Appetite. 2015 Feb;85:14-21. PubMed PMID: 25447016
  • Sazonova N, Browning R, Melanson E, Sazonov E. Posture and activity recognition and energy expenditure prediction in a wearable platform. Conf Proc IEEE Eng Med Biol Soc. 2014 Aug;2014:4163-7. PubMed PMID: 25570909
  • Rudroff T, Holmes MR, Melanson EL, Kelsey MM. Sex differences in time to task failure during early pubertal development. Muscle Nerve. 2014 Jun;49(6):887-94. PubMed PMID: 24037802
  • McHill AW, Melanson EL, Higgins J, Connick E, Moehlman TM, Stothard ER, Wright KP Jr. Impact of circadian misalignment on energy metabolism during simulated nightshift work. Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17302-7. PubMed PMID: 25404342
  • Lyden K, Swibas T, Catenacci V, Guo R, Szuminsky N, Melanson EL. Estimating energy expenditure using heat flux measured at a single body site. Med Sci Sports Exerc. 2014 Nov;46(11):2159-67. PubMed PMID: 24811326
  • Sazonova N, Browning R, Melanson E, Sazonov E. Posture and activity recognition and energy expenditure prediction in a wearable platform. Conf Proc IEEE Eng Med Biol Soc. 2014;2014:4163-7. PubMed PMID: 25570909
  • Sevits KJ, Melanson EL, Swibas T, Binns SE, Klochak AL, Lonac MC, Peltonen GL, Scalzo RL, Schweder MM, Smith AM, Wood LM, Melby CL, Bell C. Total daily energy expenditure is increased following a single bout of sprint interval training. Physiol Rep. 2013 Oct;1(5):e00131. PubMed PMID: 24303194
  • Rudroff T, Holmes MR, Melanson EL, Kelsey MM. Sex differences in time to task failure during early pubertal development. Muscle Nerve. 2013 Sep 13. [Epub ahead of print] PubMed PMID: 24037802
  • McFadden KL, Cornier MA, Melanson EL, Bechtell JL, Tregellas JR. Effects of exercise on resting-state default mode and salience network activity in overweight/obese adults. Neuroreport. 2013 Oct 23;24(15):866-71. PubMed PMID: 24022176
  • Dannecker KL, Sazonova NA, Melanson EL, Sazonov ES, Browning RC. A comparison of energy expenditure estimation of several physical activity monitors. Med Sci Sports Exerc. 2013 Nov;45(11):2105-12. PubMed PMID: 23669877
  • Markwald RR, Melanson EL, Smith MR, Higgins J, Perreault L, Eckel RH, Wright KP Jr. Impact of insufficient sleep on total daily energy expenditure, food intake, and weight gain. Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5695-700. PubMed PMID: 23479616
  • Melanson EL, Keadle SK, Donnelly JE, Braun B, King NA. Resistance to exercise-induced weight loss: compensatory behavioral adaptations. Med Sci Sports Exerc. 2013 Aug;45(8):1600-9. PubMed PMID: 23470300
  • Rudroff T, Kelsey MM, Melanson EL, McQueen MB, Enoka RM. Associations between neuromuscular function and levels of physical activity differ for boys and girls during puberty. J Pediatr. 2013 Aug;163(2):349-54. PubMed PMID: 23415611
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Practice Locations

University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

Hospital Affiliation
  • University of Colorado Hospital
Center Affiliations

Specialty Information

Specialties
  • Psychology
Conditions & Treatments
  • Food, Nutrition and Metabolism

General Information

Graduate Schools:
  • PhD, University of Massachusetts Amherst (1999)
  • MS, University of Massachusetts Amherst (1994)
Languages: English
Department: Medicine-Endocrinology/Metabolism/Diabetes
;