Paul Wadwa, MD
Professor, Pediatrics-Barbara Davis Center

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Medical School:
  • MD, Northwestern University The Feinberg School of Medicine (1996)
Undergraduate School:
  • BS, Northwestern University (IL) (1992)
Internship:
  • Nationwide Children's Hospital/Ohio State University Program (1997)
Residency:
  • Nationwide Children's Hospital/Ohio State University Program, Chief Resident, Pediatrics (2000)
Fellowships:
  • Cincinnati Children's Hospital Medical Center Program, Pediatric Endocrinology (2003)
Languages: English
Department: Pediatrics-Barbara Davis Center

Professional Titles

  • Professor of Pediatrics
  • Director, Pediatric Clinic, Barbara Davis Center
  • Director of Telemedicine, Barbara Davis Center

Recognition & Awards

  • O'Brien Fellowship Award, Children's Diabetes Foundation/ Barbara Davis Center (2015)

Research Interests

My primary research focus is on the development of the artificial pancreas for patients with type 1 diabetes. I am involved in many clinical research studies with the goal of advancing artificial pancreas technology. I am also engaged in clinical trials of new therapeutic agents as well as research describing the effects of a clinical telemedicine program on diabetes control for youth with type 1 diabetes. My hope is that the research I am involved with will greatly improve the tools available to optimize control and reduce the burden of diabetes for patients locally and beyond.

Publications

  • Breton MD, Kanapka LG, Beck RW, Ekhlaspour L, Forlenza GP, Cengiz E, Schoelwer M, Ruedy KJ, Jost E, Carria L, Emory E, Hsu LJ, Oliveri M, Kollman CC, Dokken BB, Weinzimer SA, DeBoer MD, Buckingham BA, Cherñavvsky D, Wadwa RP. A Randomized Trial of Closed-Loop Control in Children with Type 1 Diabetes. N Engl J Med. 2020 Aug 27;383(9):836-845. PubMed PMID: 32846062
  • Semova I, Levenson AE, Krawczyk J, Bullock K, Williams KA, Wadwa RP, Khoury PR, Kimball TR, Urbina EM, de Ferranti SD, Maahs DM, Dolan LM, Shah AS, Clish CB, Biddinger SB. Markers of cholesterol synthesis are elevated in adolescents and young adults with type 2 diabetes. Pediatr Diabetes. 2020 Aug 1. [Epub ahead of print] PubMed PMID: 32738021
  • Bode BW, Cengiz E, Wadwa RP, Banks P, Danne T, Kushner JA, McGuire DK, Peters A, Strumph P, Sawhney S. Effects of Sotagliflozin Combined with Intensive Insulin Therapy in Young Adults with Poorly Controlled Type 1 Diabetes: The JDRF Sotagliflozin Study. Diabetes Technol Ther. 2020 Jul 8. [Epub ahead of print] PubMed PMID: 32640846
  • Laffel LM, Kanapka LG, Beck RW, Bergamo K, Clements MA, Criego A, DeSalvo DJ, Goland R, Hood K, Liljenquist D, Messer LH, Monzavi R, Mouse TJ, Prahalad P, Sherr J, Simmons JH, Wadwa RP, Weinstock RS, Willi SM, Miller KM. Effect of Continuous Glucose Monitoring on Glycemic Control in Adolescents and Young Adults With Type 1 Diabetes: A Randomized Clinical Trial. JAMA. 2020 Jun 16;323(23):2388-2396. PubMed PMID: 32543683
  • Brown SA, Beck RW, Raghinaru D, Buckingham BA, Laffel LM, Wadwa RP, Kudva YC, Levy CJ, Pinsker JE, Dassau E, Doyle FJ 3rd, Ambler-Osborn L, Anderson SM, Church MM, Ekhlaspour L, Forlenza GP, Levister C, Simha V, Breton MD, Kollman C, Lum JW, Kovatchev BP. Glycemic Outcomes of Use of CLC Versus PLGS in Type 1 Diabetes: A Randomized Controlled Trial. Diabetes Care. 2020 Aug;43(8):1822-1828. PubMed PMID: 32471910
  • Jensen ET, Dabelea DA, Praveen PA, Amutha A, Hockett CW, Isom SP, Ong TC, Mohan V, D'Agostino R Jr, Kahn MG, Hamman RF, Wadwa P, Dolan L, Lawrence JM, Madhu SV, Chhokar R, Goel K, Tandon N, Mayer-Davis E. Comparison of the incidence of diabetes in United States and Indian youth: An international harmonization of youth diabetes registries. Pediatr Diabetes. 2020 Mar 20. [Epub ahead of print] PubMed PMID: 32196874
  • Amutha A, Praveen PA, Hockett CW, Ong TC, Jensen ET, Isom SP, D'Agostino RBJ, Hamman RF, Mayer-Davis EJ, Wadwa RP, Lawrence JM, Pihoker C, Kahn MG, Dabelea D, Tandon N, Mohan V. Treatment regimens and glycosylated hemoglobin levels in youth with Type 1 and Type 2 diabetes: Data from SEARCH (United States) and YDR (India) registries. Pediatr Diabetes. 2020 Mar 5. [Epub ahead of print] PubMed PMID: 32134536
  • DiMeglio LA, Kanapka LG, DeSalvo DJ, Anderson BJ, Harrington KR, Hilliard ME, Laffel LM, Tamborlane WV, Van Name MA, Wadwa RP, Willi SM, Woerner S, Wong JC, Miller KM. Time spent outside of target glucose range for young children with type 1 diabetes: a continuous glucose monitor study. Diabet Med. 2020 Aug;37(8):1308-1315. PubMed PMID: 32096282
  • Kovatchev B, Anderson SM, Raghinaru D, Kudva YC, Laffel LM, Levy C, Pinsker JE, Wadwa RP, Buckingham B, Doyle FJ 3rd, Brown SA, Church MM, Dadlani V, Dassau E, Ekhlaspour L, Forlenza GP, Isganaitis E, Lam DW, Lum J, Beck RW. Randomized Controlled Trial of Mobile Closed-Loop Control. Diabetes Care. 2020 Mar;43(3):607-615. PubMed PMID: 31937608
  • Messer LH, Berget C, Vigers T, Pyle L, Geno C, Wadwa RP, Driscoll KA, Forlenza GP. Real world hybrid closed-loop discontinuation: Predictors and perceptions of youth discontinuing the 670G system in the first 6 months. Pediatr Diabetes. 2020 Mar;21(2):319-327. PubMed PMID: 31885123
  • Berget C, Messer LH, Vigers T, Frohnert BI, Pyle L, Wadwa RP, Driscoll KA, Forlenza GP. Six months of hybrid closed loop in the real-world: An evaluation of children and young adults using the 670G system. Pediatr Diabetes. 2020 Mar;21(2):310-318. PubMed PMID: 31837064
  • Hilliard ME, Minard CG, Marrero DG, de Wit M, Thompson D, DuBose SN, Verdejo A, Monzavi R, Wadwa RP, Jaser SS, Anderson BJ. Assessing Health-Related Quality of Life in Children and Adolescents with Diabetes: Development and Psychometrics of the Type 1 Diabetes and Life (T1DAL) Measures. J Pediatr Psychol. 2020 Apr 1;45(3):328-339. PubMed PMID: 31665389
  • Sherr JL, Buckingham BA, Forlenza GP, Galderisi A, Ekhlaspour L, Wadwa RP, Carria L, Hsu L, Berget C, Peyser TA, Lee JB, O'Connor J, Dumais B, Huyett LM, Layne JE, Ly TT. Safety and Performance of the Omnipod Hybrid Closed-Loop System in Adults, Adolescents, and Children with Type 1 Diabetes Over 5 Days Under Free-Living Conditions. Diabetes Technol Ther. 2020 Mar;22(3):174-184. PubMed PMID: 31596130
  • Berget C, Thomas SE, Messer LH, Thivener K, Slover RH, Wadwa RP, Alonso GT. A Clinical Training Program for Hybrid Closed Loop Therapy in a Pediatric Diabetes Clinic. J Diabetes Sci Technol. 2020 Mar;14(2):290-296. PubMed PMID: 30862242
  • Wadwa RP, Matsuhisa M, Zhang N, Thieu V, Wang Q, Ohwaki K, Child C, Threlkeld R, Choudhary P. Nasal glucagon successfully revered insulin-induced hypoglycemia in adults with diabetes with nadir blood glucose less than 3.0 mmol/L (54 mg/dl): a pooled analysis. Diabetes Technol Ther. 2020 Feb; 22(S1): A26.
  • Wong J, Hanes S, Forlenza G, Weber I, Wadwa RP, Buckingham B, Hood K. Early initiation of continuous glucose monitoring among children and adolescents: Benefits and timing. Diabetes Technol Ther. 2020 Feb; 22(S1): A146-7.
  • Hanes S, Wadwa RP, Weber I, Wong J, Forlenza G, Buckingham B, Hood K. Continuous glucose monitoring (CGM) initiate at diagnosis versus six months later: which is best? Diabetes Technol Ther. 2020 Feb; 22(S1): A128-9.
  • Cobry ED, Reznick-Lipina T, Pyle L, Slover RH, Thomas JF, Alonso GT, Wadwa RP. Lower use of technology in youth with type 1 diabetes in locations distant from specialty care. Diabetes 2020 Jun; 69(S1). https://doi.org/10.2337/db20-1321-P. Poster at 2020 Virtual ADA Scientific Sessions.
  • O’Donnell H, Alonso GT, Gomer T, Majidi S, Snell-Bergeon JK, Reznick-Lipina T, Wadwa RP, Driscoll KA. Fully integreated medical and psychological intervention for T1D self-management in adolescents: trial design and baseline characteristics. Diabetes 2020 Jun; 69(Supplement 1). https://doi.org/10.2337/db20-774-P.
  • Ekhlaspour L, Forlenza GP, Schoelwer M, DeBoer MD, Hsu L, Kingman RS, Boranian E, Emory E, Wadwa RP, Buckingham BA, Breton MD. Safety and performance of the Tandem t:slim X2 with Control-IQ automated insulin delivery system in preschoolers age 2-6 years old. Diabetes 2020 Jun; 69(Supplement 1). https://doi.org/10.2337/db20-195-OR.
  • Cobry EC, Berget C, Messer LH, Wadwa RP, Vigers TB, Pyle L, Slover RH, Driscoll KA, Forlenza GP. Nocturnal alarms: a potential barrier to diabetes technology use. Diabetes 2020 Jun; 69(Supplement 1). https://doi.org/10.2337/db20-157-LB.
  • Brown SA, Raghinaru D. Buckingham BA, Kudva YC, Laffel LM, Levy CJ, Pinsker JE, Wadwa RP, Lum J, Kollman C, Beck R, Kovatchev B. Eighteen-month use of closed-loop control (CLC): a randomized, controlled trial. Diabetes 2020 Jun; 69(Supplement 1). https://doi.org/10.2337/db20-101-LB.
  • Sherr J, Buckingham BA, Forlenza GP, Galderisi A, Ekhlaspour L, Wadwa RP, Zgorski M, Kingman RS, Berget C, Lee JB, OConnor JB, Dumais B, Vienneay T, Huyett LM, Ly TT. Omnipod personalized MPC algorithm at target glucose of 110 mg/dl is safe in children aged 2-12 years without increasing risk of hypoglycemia. Diabetes 2020 Jun; 69(Supplement 1). https://doi.org/10.2337/db20-1296-LB.
  • Forlenza GP, Buckingham BA, Sherr J, Wadwa RP, Galderisi A, Ekhlaspour L, Berget C, Hsu L, Zgorski M, Lee JB, OConnor JB, Dumais B, Vienneay T, Huyett LM, Ly TT. Omnipod personalized MPC algorithm at target glucose of 110 mg/dl is safe in adults and adolescents without increasing risk of hypoglycemia. Diabetes 2020 Jun; 69(Supplement 1). https://doi.org/10.2337/db20-978-P.
  • Breton MD, Kanapka LG, Beck RW, Ekhlaspour L, Forlenza GP, Cengiz E, Schoelwer M, Reudy K, Kollman CC, Weinzimer SA, DeBoer M, Buckingham BA, Chernavvsky D, Wadwa RP for the iDCL Trial Research Group. Glycemic control improves over 4 month use of closed loop insulin delivery in school-age children with type 1 diabetes. www.easd.org
  • Messer LH, Berget C. Towers L, Otten B, Ernst A, Karami A, Thomas S, Cobry E, Alonso GT, Slover R, Wadwa P, Forlenza G for the PANTHER technology program. Evaluation of the hybrid closed-loop check-in program by diabetes educators. Pediatr Diabetes 2020.
  • Semova I, Levenson AE, Krawczyk J, Bullock K, Williams KA, Wadwa RP, Shah AS, Khoury PR, Kimball TR, Urbina EM, de Ferranti SD, Bishop FK, Maahs DM, Dolan LM, Clish CB, Biddinger SB. Type 1 diabetes is associated with an increase in cholesterol absorption markers but a decrease in cholesterol synthesis markers in a young adult population. J Clin Lipidol. 2019 Sep 25. [Epub ahead of print] PubMed PMID: 31706902
  • Hilliard ME, Minard CG, Marrero DG, de Wit M, Thompson D, DuBose SN, Verdejo A, Monzavi R, Wadwa RP, Jaser SS, Anderson BJ. Assessing Health-Related Quality of Life in Children and Adolescents with Diabetes: Development and Psychometrics of the Type 1 Diabetes and Life (T1DAL) Measures. J Pediatr Psychol. 2019 Oct 29. [Epub ahead of print] PubMed PMID: 31665389
  • Brown SA, Kovatchev BP, Raghinaru D, Lum JW, Buckingham BA, Kudva YC, Laffel LM, Levy CJ, Pinsker JE, Wadwa RP, Dassau E, Doyle FJ 3rd, Anderson SM, Church MM, Dadlani V, Ekhlaspour L, Forlenza GP, Isganaitis E, Lam DW, Kollman C, Beck RW. Six-Month Randomized, Multicenter Trial of Closed-Loop Control in Type 1 Diabetes. N Engl J Med. 2019 Oct 31;381(18):1707-1717. PubMed PMID: 31618560
  • Gourgari E, Stafford JM, D'Agostino R Jr, Dolan LM, Lawrence JM, Mottl A, Pihoker C, Urbina EM, Wadwa RP, Dabelea D. Association of metformin and statin medications with surrogate measures of cardiovascular disease in youth with type 1 diabetes: the SEARCH for diabetes in youth study. Ann Pediatr Endocrinol Metab. 2019 Sep;24(3):187-194. PubMed PMID: 31607112
  • Sherr JL, Buckingham BA, Forlenza GP, Galderisi A, Ekhlaspour L, Wadwa RP, Carria L, Hsu L, Berget C, Peyser TA, Lee JB, O'Connor J, Dumais B, Huyett LM, Layne JE, Ly TT. Safety and Performance of the Omnipod Hybrid Closed-Loop System in Adults, Adolescents, and Children with Type 1 Diabetes Over 5 Days Under Free-Living Conditions. Diabetes Technol Ther. 2019 Oct 29. [Epub ahead of print] PubMed PMID: 31596130
  • Wiromrat P, Bjornstad P, Vinovskis C, Chung LT, Roncal C, Pyle L, Lanaspa MA, Johnson RJ, Cherney DZ, Reznick-Lipina TK, Bishop F, Maahs DM, Wadwa RP. Elevated copeptin, arterial stiffness, and elevated albumin excretion in adolescents with type 1 diabetes. Pediatr Diabetes. 2019 Dec;20(8):1110-1117. PubMed PMID: 31433534
  • Wiromrat P, Bjornstad P, Roncal C, Pyle L, Johnson RJ, Cherney DZ, Lipina T, Bishop F, Maahs DM, Wadwa RP. Serum uromodulin is associated with urinary albumin excretion in adolescents with type 1 diabetes. J Diabetes Complications. 2019 Sep;33(9):648-650. PubMed PMID: 31253490
  • Urbina EM, Isom S, Bell RA, Bowlby DA, D'Agostino R Jr, Daniels SR, Dolan LM, Imperatore G, Marcovina SM, Merchant AT, Reynolds K, Shah AS, Wadwa RP, Dabelea D. Burden of Cardiovascular Risk Factors Over Time and Arterial Stiffness in Youth With Type 1 Diabetes Mellitus: The SEARCH for Diabetes in Youth Study. J Am Heart Assoc. 2019 Jul 2;8(13):e010150. PubMed PMID: 31213111
  • Musolino G, Allen JM, Hartnell S, Wilinska ME, Tauschmann M, Boughton C, Campbell F, Denvir L, Trevelyan N, Wadwa P, DiMeglio L, Buckingham BA, Weinzimer S, Acerini CL, Hood K, Fox S, Kollman C, Sibayan J, Borgman S, Cheng P, Hovorka R. Assessing the efficacy, safety and utility of 6-month day-and-night automated closed-loop insulin delivery under free-living conditions compared with insulin pump therapy in children and adolescents with type 1 diabetes: an open-label, multicentre, multinational, single-period, randomised, parallel group study protocol. BMJ Open. 2019 Jun 3;9(6):e027856. PubMed PMID: 31164368
  • Forlenza GP, Buckingham BA, Christiansen MP, Wadwa RP, Peyser TA, Lee JB, O'Connor J, Dassau E, Huyett LM, Layne JE, Ly TT. Performance of Omnipod Personalized Model Predictive Control Algorithm with Moderate Intensity Exercise in Adults with Type 1 Diabetes. Diabetes Technol Ther. 2019 May;21(5):265-272. PubMed PMID: 30925077
  • Ekhlaspour L, Forlenza GP, Chernavvsky D, Maahs DM, Wadwa RP, Deboer MD, Messer LH, Town M, Pinnata J, Kruse G, Kovatchev BP, Buckingham BA, Breton MD. Closed loop control in adolescents and children during winter sports: Use of the Tandem Control-IQ AP system. Pediatr Diabetes. 2019 Sep;20(6):759-768. PubMed PMID: 31099946
  • Forlenza GP, Ekhlaspour L, Breton M, Maahs DM, Wadwa RP, DeBoer M, Messer LH, Town M, Pinnata J, Kruse G, Buckingham BA, Cherñavvsky D. Successful At-Home Use of the Tandem Control-IQ Artificial Pancreas System in Young Children During a Randomized Controlled Trial. Diabetes Technol Ther. 2019 Apr;21(4):159-169. PubMed PMID: 30888835
  • Berget C, Thomas SE, Messer LH, Thivener K, Slover RH, Wadwa RP, Alonso GT. A Clinical Training Program for Hybrid Closed Loop Therapy in a Pediatric Diabetes Clinic. J Diabetes Sci Technol. 2019 Mar 12;:1932296819835183. [Epub ahead of print] PubMed PMID: 30862242
  • Forlenza GP, Kushner T, Messer LH, Wadwa RP, Sankaranarayanan S. Factory-Calibrated Continuous Glucose Monitoring: How and Why It Works, and the Dangers of Reuse Beyond Approved Duration of Wear. Diabetes Technol Ther. 2019 Apr;21(4):222-229. PubMed PMID: 30817171
  • Sopfe J, Pyle L, Keating AK, Campbell K, Liu AK, Wadwa RP, Verneris MR, Giller RH, Forlenza GP. Malglycemia is associated with poor outcomes in pediatric and adolescent hematopoietic stem cell transplant patients. Blood Adv. 2019 Feb 12;3(3):350-359. PubMed PMID: 30718242
  • Anderson SM, Dassau E, Raghinaru D, Lum J, Brown SA, Pinsker JE, Church MM, Levy C, Lam D, Kudva YC, Buckingham B, Forlenza GP, Wadwa RP, Laffel L, Doyle FJ 3rd, DeVries JH, Renard E, Cobelli C, Boscari F, Del Favero S, Kovatchev BP. The International Diabetes Closed-Loop Study: Testing Artificial Pancreas Component Interoperability. Diabetes Technol Ther. 2019 Feb;21(2):73-80. PubMed PMID: 30649925
  • Berget C, Messer LH, Vigers T, Frohnert BI, Pyle L, Wadwa RP, Driscoll KA, Forlenza GP. Six months of Hybrid Closed Loop in the Real-World: An Evaluation of Children and Young Adults using the 670G System. Pediatr Diabetes. 2019 Dec 13. [Epub ahead of print] PubMed PMID: 31837064
  • Semova I, Levenson AE, Krawczyk J, Bullock K, Williams KA, Wadwa RP, Shah AS, Khoury PR, Kimball TR, Urbina EM, de Ferranti SD, Bishop FK, Maahs DM, Dolan LM, Clish CB, Biddinger SB. Type 1 diabetes is associated with an increase in cholesterol absorption markers but a decrease in cholesterol synthesis markers in a young adult population. J Clin Lipidol. 2019 Nov - Dec;13(6):940-946. PubMed PMID: 31706902
  • Brown SA, Kovatchev BP, Raghinaru D, Lum JW, Buckingham BA, Kudva YC, Laffel LM, Levy CJ, Pinsker JE, Wadwa RP, Dassau E, Doyle FJ 3rd, Anderson SM, Church MM, Dadlani V, Ekhlaspour L, Forlenza GP, Isganaitis E, Lam DW, Kollman C, Beck RW. Six-Month Randomized, Multicenter Trial of Closed-Loop Control in Type 1 Diabetes. N Engl J Med. 2019 Oct 31;381(18):1707-1717. PubMed PMID: 31618560
  • Wiromrat P, Bjornstad P, Vinovskis C, Chung LT, Roncal C, Pyle L, Lanaspa MA, Johnson RJ, Cherney DZ, Reznick-Lipina TK, Bishop F, Maahs DM, Wadwa RP. Elevated copeptin, arterial stiffness, and elevated albumin excretion in adolescents with type 1 diabetes. Pediatr Diabetes. 2019 Dec;20(8):1110-1117. PubMed PMID: 31433534
  • Alman AC, Talton JW, Wadwa RP, Urbina EM, Dolan LM, Hamman RF, D'Agostino RB Jr, Marcovina SM, Dabelea DM. Inflammation, adiposity, and progression of arterial stiffness in adolescents with type 1 diabetes: The SEARCH CVD Study. J Diabetes Complications. 2018 Nov;32(11):995-999. PubMed PMID: 30209019
  • Forlenza GP, Li Z, Buckingham BA, Pinsker JE, Cengiz E, Wadwa RP, Ekhlaspour L, Church MM, Weinzimer SA, Jost E, Marcal T, Andre C, Carria L, Swanson V, Lum JW, Kollman C, Woodall W, Beck RW. Predictive Low-Glucose Suspend Reduces Hypoglycemia in Adults, Adolescents, and Children With Type 1 Diabetes in an At-Home Randomized Crossover Study: Results of the PROLOG Trial. Diabetes Care. 2018 Oct;41(10):2155-2161. PubMed PMID: 30089663
  • Buckingham BA, Christiansen MP, Forlenza GP, Wadwa RP, Peyser TA, Lee JB, O'Connor J, Dassau E, Huyett LM, Layne JE, Ly TT. Performance of the Omnipod Personalized Model Predictive Control Algorithm with Meal Bolus Challenges in Adults with Type 1 Diabetes. Diabetes Technol Ther. 2018 Sep;20(9):585-595. PubMed PMID: 30070928
  • Forlenza GP, Cameron FM, Ly TT, Lam D, Howsmon DP, Baysal N, Kulina G, Messer L, Clinton P, Levister C, Patek SD, Levy CJ, Wadwa RP, Maahs DM, Bequette BW, Buckingham BA. Fully Closed-Loop Multiple Model Probabilistic Predictive Controller Artificial Pancreas Performance in Adolescents and Adults in a Supervised Hotel Setting. Diabetes Technol Ther. 2018 May;20(5):335-343. PubMed PMID: 29658779
  • Buckingham BA, Forlenza GP, Pinsker JE, Christiansen MP, Wadwa RP, Schneider J, Peyser TA, Dassau E, Lee JB, O'Connor J, Layne JE, Ly TT. Safety and Feasibility of the OmniPod Hybrid Closed-Loop System in Adult, Adolescent, and Pediatric Patients with Type 1 Diabetes Using a Personalized Model Predictive Control Algorithm. Diabetes Technol Ther. 2018 Apr;20(4):257-262. PubMed PMID: 29431513
  • Bjornstad P, Schäfer M, Truong U, Cree-Green M, Pyle L, Baumgartner A, Garcia Reyes Y, Maniatis A, Nayak S, Wadwa RP, Browne LP, Reusch JEB, Nadeau KJ. Metformin Improves Insulin Sensitivity and Vascular Health in Youth With Type 1 Diabetes Mellitus. Circulation. 2018 Dec 18;138(25):2895-2907. PubMed PMID: 30566007
  • Alman AC, Talton JW, Wadwa RP, Urbina EM, Dolan LM, Hamman RF, D'Agostino RB Jr, Marcovina SM, Dabelea DM. Inflammation, adiposity, and progression of arterial stiffness in adolescents with type 1 diabetes: The SEARCH CVD Study. J Diabetes Complications. 2018 Nov;32(11):995-999. PubMed PMID: 30209019
  • Donaghue KC, Marcovecchio ML, Wadwa RP, Chew EY, Wong TY, Calliari LE, Zabeen B, Salem MA, Craig ME. ISPAD Clinical Practice Consensus Guidelines 2018: Microvascular and macrovascular complications in children and adolescents. Pediatr Diabetes. 2018 Oct;19 Suppl 27:262-274. PubMed PMID: 30079595
  • Breton MD, Cherñavvsky DR, Forlenza GP, DeBoer MD, Robic J, Wadwa RP, Messer LH, Kovatchev BP, Maahs DM. Closed-Loop Control During Intense Prolonged Outdoor Exercise in Adolescents With Type 1 Diabetes: The Artificial Pancreas Ski Study. Diabetes Care. 2017 Dec;40(12):1644-1650. PubMed PMID: 28855239
  • Levenson AE, Shah AS, Khoury PR, Kimball TR, Urbina EM, de Ferranti SD, Maahs DM, Dolan LM, Wadwa RP, Biddinger SB. Obesity and type 2 diabetes are associated with elevated PCSK9 levels in young women. Pediatr Diabetes. 2017 Dec;18(8):755-760. PubMed PMID: 28093849
  • Wadwa RP, Chase HP, Raghinaru D, Buckingham BA, Hramiak I, Maahs DM, Messer L, Ly T, Aye T, Clinton P, Kollman C, Beck RW, Lum J. Ketone production in children with type 1 diabetes, ages 4-14 years, with and without nocturnal insulin pump suspension. Pediatr Diabetes. 2017 Sep;18(6):422-427. PubMed PMID: 27402452
  • Wood CL, Clements SA, McFann K, Slover R, Thomas JF, Wadwa RP. Use of Telemedicine to Improve Adherence to American Diabetes Association Standards in Pediatric Type 1 Diabetes. Diabetes Technol Ther. 2016 Jan;18(1):7-14. PubMed PMID: 26295939
  • Nambam B, DuBose SN, Nathan BM, Beck RW, Maahs DM, Wadwa RP, Tamborlane WV, Foster NC, Miller KM, Haller MJ. Therapeutic inertia: underdiagnosed and undertreated hypertension in children participating in the T1D Exchange Clinic Registry. Pediatr Diabetes. 2016 Feb;17(1):15-20. PubMed PMID: 25330905
  • Karlin AW, Ly TT, Pyle L, Forlenza GP, Messer L, Wadwa RP, DeSalvo DJ, Payne SL, Hanes S, Clinton P, Maahs DM, Buckingham B. Duration of Infusion Set Survival in Lipohypertrophy Versus Nonlipohypertrophied Tissue in Patients with Type 1 Diabetes. Diabetes Technol Ther. 2016 Jul;18(7):429-35. PubMed PMID: 27227290
  • DeSalvo DJ, Ly TT, Wadwa RP, Messer L, Westfall E, Gopisetty D, Hanes S, von Eyben R, Maahs DM, Buckingham BA. Continuous Glucose Sensor Survival and Accuracy Over 14 Consecutive Days. Diabetes Care. 2016 Aug;39(8):e112-3. PubMed PMID: 27222506
  • Ljunggren P, Maahs DM, Johansson P, Ludvigsson J, Pyle L, Sippl R, Wadwa RP, Snell-Bergeon J. Reduced brachial artery distensibility in patients with type 1 diabetes. J Diabetes Complications. 2016 Jul;30(5):893-7. PubMed PMID: 27056753
  • Sherr JL, Ruedy KJ, Foster NC, Piché CA, Dulude H, Rickels MR, Tamborlane WV, Bethin KE, DiMeglio LA, Fox LA, Wadwa RP, Schatz DA, Nathan BM, Marcovina SM, Rampakakis E, Meng L, Beck RW. Glucagon Nasal Powder: A Promising Alternative to Intramuscular Glucagon in Youth With Type 1 Diabetes. Diabetes Care. 2016 Apr;39(4):555-62. PubMed PMID: 26884472
  • Shah AS, Dabelea D, Fino NF, Dolan LM, Wadwa RP, D'Agostino R Jr, Hamman R, Marcovina S, Daniels SR, Urbina EM. Predictors of Increased Carotid Intima-Media Thickness in Youth With Type 1 Diabetes: The SEARCH CVD Study. Diabetes Care. 2016 Mar;39(3):418-25. PubMed PMID: 26721813
  • Bjornstad P, Roncal C, Milagres T, Pyle L, Lanaspa MA, Bishop FK, Snell-Bergeon JK, Johnson RJ, Wadwa RP, Maahs DM. Hyperfiltration and uricosuria in adolescents with type 1 diabetes. Pediatr Nephrol. 2016 May;31(5):787-93. PubMed PMID: 26701836
  • Rickels MR, Ruedy KJ, Foster NC, Piché CA, Dulude H, Sherr JL, Tamborlane WV, Bethin KE, DiMeglio LA, Wadwa RP, Ahmann AJ, Haller MJ, Nathan BM, Marcovina SM, Rampakakis E, Meng L, Beck RW. Intranasal Glucagon for Treatment of Insulin-Induced Hypoglycemia in Adults With Type 1 Diabetes: A Randomized Crossover Noninferiority Study. Diabetes Care. 2016 Feb;39(2):264-70. PubMed PMID: 26681725
  • Merchant AT, Nahhas GJ, Wadwa RP, Zhang J, Tang Y, Johnson LR, Maahs DM, Bishop F, Teles R, Morrato EH. Periodontal Microorganisms and Cardiovascular Risk Markers in Youth With Type 1 Diabetes and Without Diabetes. J Periodontol. 2016 Apr;87(4):376-84. PubMed PMID: 26616842
  • Nambam B, DuBose SN, Nathan BM, Beck RW, Maahs DM, Wadwa RP, Tamborlane WV, Foster NC, Miller KM, Haller MJ. Therapeutic inertia: underdiagnosed and undertreated hypertension in children participating in the T1D Exchange Clinic Registry. Pediatr Diabetes. 2016 Feb;17(1):15-20. PubMed PMID: 25330905
  • Shah AS, Dabelea D, Fino NF, Dolan LM, Wadwa RP, D'Agostino R Jr, Hamman R, Marcovina S, Daniels SR, Urbina EM. Predictors of Increased Carotid Intima Media Thickness in Youth With Type 1 Diabetes: The SEARCH CVD Study. Diabetes Care. 2015 Dec 30. [Epub ahead of print] PubMed PMID: 26721813
  • Bjornstad P, Roncal C, Milagres T, Pyle L, Lanaspa MA, Bishop FK, Snell-Bergeon JK, Johnson RJ, Wadwa RP, Maahs DM. Hyperfiltration and uricosuria in adolescents with type 1 diabetes. Pediatr Nephrol. 2015 Dec 23. [Epub ahead of print] PubMed PMID: 26701836
  • Rickels MR, Ruedy KJ, Foster NC, Piché CA, Dulude H, Sherr JL, Tamborlane WV, Bethin KE, DiMeglio LA, Wadwa RP, Ahmann AJ, Haller MJ, Nathan BM, Marcovina SM, Rampakakis E, Meng L, Beck RW. Intranasal Glucagon for Treatment of Insulin-Induced Hypoglycemia in Adults With Type 1 Diabetes: A Randomized Crossover Noninferiority Study. Diabetes Care. 2015 Dec 17. [Epub ahead of print] PubMed PMID: 26681725
  • Merchant AT, Nahhas GJ, Wadwa RP, Zhang J, Tang Y, Johnson LR, Maahs DM, Bishop F, Teles R, Morrato EH. Periodontal Microorganisms and Cardiovascular Risk Markers in Youth With Type 1 Diabetes and No Diabetes. J Periodontol. 2015 Nov 28;:1-11. [Epub ahead of print] PubMed PMID: 26616842
  • DeSalvo DJ, Maahs DM, Messer L, Wadwa RP, Payne S, Ly TT, Buckingham BA. Effect of lipohypertrophy on accuracy of continuous glucose monitoring in patients with type 1 diabetes. Diabetes Care. 2015 Oct;38(10):e166-7. PubMed PMID: 26307604
  • Buckingham BA, Raghinaru D, Cameron F, Bequette BW, Chase HP, Maahs DM, Slover R, Wadwa RP, Wilson DM, Ly T, Aye T, Hramiak I, Clarson C, Stein R, Gallego PH, Lum J, Sibayan J, Kollman C, Beck RW. Erratum. Predictive Low-Glucose Insulin Suspension Reduces Duration of Nocturnal Hypoglycemia in Children Without Increasing Ketosis. Diabetes Care 2015;38:1197-1204. Diabetes Care. 2015 Sep;38(9):1813. PubMed PMID: 26294776
  • Maahs DM, DeSalvo D, Pyle L, Ly T, Messer L, Clinton P, Westfall E, Wadwa RP, Buckingham B. Effect of acetaminophen on CGM glucose in an outpatient setting. Diabetes Care. 2015 Oct;38(10):e158-9. PubMed PMID: 26269199
  • Buckingham BA, Raghinaru D, Cameron F, Bequette BW, Chase HP, Maahs DM, Slover R, Wadwa RP, Wilson DM, Ly T, Aye T, Hramiak I, Clarson C, Stein R, Gallego PH, Lum J, Sibayan J, Kollman C, Beck RW. Predictive Low-Glucose Insulin Suspension Reduces Duration of Nocturnal Hypoglycemia in Children Without Increasing Ketosis. Diabetes Care. 2015 Jul;38(7):1197-204. PubMed PMID: 26049549
  • Shah AS, Wadwa RP, Dabelea D, Hamman RF, D'Agostino R Jr, Marcovina S, Daniels SR, Dolan LM, Fino NF, Urbina EM. Arterial stiffness in adolescents and young adults with and without type 1 diabetes: the SEARCH CVD study. Pediatr Diabetes. 2015 Aug;16(5):367-74. PubMed PMID: 25912292
  • Shah AS, Black S, Wadwa RP, Schmiege SJ, Fino NF, Talton JW, D'Agostino R Jr, Hamman RF, Urbina EM, Dolan LM, Daniels SR, Marcovina SM, Dabelea D. Insulin sensitivity and arterial stiffness in youth with type 1 diabetes: the SEARCH CVD study. J Diabetes Complications. 2015 May-Jun;29(4):512-6. PubMed PMID: 25736026
  • Bjornstad P, Pyle L, Nguyen N, Snell-Bergeon JK, Bishop FK, Wadwa RP, Maahs DM. Achieving International Society for Pediatric and Adolescent Diabetes and American Diabetes Association clinical guidelines offers cardiorenal protection for youth with type 1 diabetes. Pediatr Diabetes. 2015 Feb;16(1):22-30. PubMed PMID: 25604668
  • Shah AS, Dolan LM, Dabelea D, Stafford JM, D'Agostino RB Jr, Mayer-Davis EJ, Marcovina S, Imperatore G, Wadwa RP, Daniels SR, Reynolds K, Hamman RF, Bowlby DA, Maahs DM. Change in adiposity minimally affects the lipid profile in youth with recent onset type 1 diabetes. Pediatr Diabetes. 2015 Jun;16(4):280-6. PubMed PMID: 25099744
  • Tamborlane WV, Renard E, Wadwa RP, Blevins T, Jacober SJ, Liu R, D'Souza DN, Rees TM. Glycemic control after 6 days of insulin pump reservoir use in type 1 diabetes: results of double-blind and open-label cross-over trials of insulin lispro and insulin aspart. J Diabetes. 2015 Mar;7(2):270-8. PubMed PMID: 24734891
  • Alman AC, Talton JW, Wadwa RP, Urbina EM, Dolan LM, Daniels SR, Hamman RF, D'Agostino RB, Marcovina SM, Mayer-Davis EJ, Dabelea DM. Cardiovascular health in adolescents with type 1 diabetes: The SEARCH CVD Study. Pediatr Diabetes. 2014 Jan 22. [Epub ahead of print] PubMed PMID: 24450411
  • Bjornstad P, Maahs DM, Wadwa RP, Pyle L, Rewers M, Eckel RH, Snell-Bergeon JK. Plasma triglycerides predict incident albuminuria and progression of coronary artery calcification in adults with type 1 diabetes: The Coronary Artery Calcification in Type 1 Diabetes Study. J Clin Lipidol. 2014 Nov-Dec;8(6):576-83. PubMed PMID: 25499940
  • Nambam B, DuBose SN, Nathan BM, Beck RW, Maahs DM, Wadwa RP, Tamborlane WV, Foster NC, Miller KM, Haller MJ, for the T1D Exchange Clinic Network. Therapeutic inertia: underdiagnosed and undertreated hypertension in children participating in the T1D Exchange Clinic Registry. Pediatr Diabetes. 2014 Oct 21. [Epub ahead of print] PubMed PMID: 25330905
  • Bishop FK, Wadwa RP, Snell-Bergeon J, Nguyen N, Maahs DM. Changes in diet and physical activity in adolescents with and without type 1 diabetes over time. Int J Pediatr Endocrinol. 2014;2014(1):17. PubMed PMID: 25191342
  • Shah AS, Dolan LM, Dabelea D, Stafford JM, D'Agostino RB Jr, Mayer-Davis EJ, Marcovina S, Imperatore G, Wadwa RP, Daniels SR, Reynolds K, Hamman RF, Bowlby DA, Maahs DM, for the SEARCH for Diabetes in Youth Study. Change in adiposity minimally affects the lipid profile in youth with recent onset type 1 diabetes. Pediatr Diabetes. 2014 Aug 7. [Epub ahead of print] PubMed PMID: 25099744
  • Majidi S, Wadwa RP, Bishop FK, Klingensmith GJ, Rewers M, McFann K, Maahs DM. The effect of insurance status and parental education on glycemic control and cardiovascular disease risk profile in youth with Type 1 Diabetes. J Diabetes Metab Disord. 2014;13:59. PubMed PMID: 24955334
  • Beck RW, Raghinaru D, Wadwa RP, Chase HP, Maahs DM, Buckingham BA, In Home Closed Loop Study Group. Frequency of morning ketosis after overnight insulin suspension using an automated nocturnal predictive low glucose suspend system. Diabetes Care. 2014 May;37(5):1224-9. PubMed PMID: 24757229
  • Tamborlane WV, Renard E, Wadwa RP, Blevins T, Jacober SJ, Liu R, D'Souza DN, Rees TM. Glycemic control after 6 days of insulin pump reservoir use in type 1 diabetes: Results of double-blind and open-label cross-over trials of insulin lispro and insulin aspart. J Diabetes. 2014 Apr 15. [Epub ahead of print] PubMed PMID: 24734891
  • Shah AS, Dabelea D, Talton JW, Urbina EM, D Agostino RB Jr, Wadwa RP, Marcovina S, Hamman RF, Daniels SR, Dolan LM. Smoking and arterial stiffness in youth with type 1 diabetes: the SEARCH Cardiovascular Disease Study. J Pediatr. 2014 Jul;165(1):110-6. PubMed PMID: 24681182
  • Jaacks LM, Crandell J, Liese AD, Lamichhane AP, Bell RA, Dabelea D, D'Agostino RB Jr, Dolan LM, Marcovina S, Reynolds K, Shah AS, Urbina EM, Wadwa RP, Mayer-Davis EJ. No association of dietary fiber intake with inflammation or arterial stiffness in youth with type 1 diabetes. J Diabetes Complications. 2014 May-Jun;28(3):305-10. PubMed PMID: 24613131
  • Bjornstad P, Snell-Bergeon JK, McFann K, Wadwa RP, Rewers M, Rivard CJ, Jalal D, Chonchol MB, Johnson RJ, Maahs DM. Serum uric acid and insulin sensitivity in adolescents and adults with and without type 1 diabetes. J Diabetes Complications. 2014 May-Jun;28(3):298-304. PubMed PMID: 24461546
  • Alman AC, Talton JW, Wadwa RP, Urbina EM, Dolan LM, Daniels SR, Hamman RF, D'Agostino RB, Marcovina SM, Mayer-Davis EJ, Dabelea DM. Cardiovascular health in adolescents with type 1 diabetes: the SEARCH CVD study. Pediatr Diabetes. 2014 Nov;15(7):502-10. PubMed PMID: 24450411
  • Jaiswal M, Urbina EM, Wadwa RP, Talton JW, D'Agostino RB Jr, Hamman RF, Fingerlin TE, Daniels S, Marcovina SM, Dolan LM, Dabelea D. Reduced Heart Rate Variability Among Youth With Type 1 Diabetes: The SEARCH CVD study. Diabetes Care. 2013 Jan;36(1):157-62. PubMed PMID: 22961570
  • Specht BJ, Wadwa RP, Snell-Bergeon JK, Nadeau KJ, Bishop FK, Maahs DM. Estimated Insulin Sensitivity and Cardiovascular Disease Risk Factors in Adolescents with and without Type 1 Diabetes. J Pediatr. 2013 Feb;162(2):297-301. PubMed PMID: 22921593
  • Maahs DM, Dabelea D, D'Agostino RB Jr, Andrews JS, Shah AS, Crimmins N, Mayer-Davis EJ, Marcovina S, Imperatore G, Wadwa RP, Daniels SR, Reynolds K, Hamman RF, Dolan LM, SEARCH for Diabetes in Youth Study. Glucose control predicts 2-year change in lipid profile in youth with type 1 diabetes. J Pediatr. 2013 Jan;162(1):101-107.e1. PubMed PMID: 22795314
  • Bjornstad P, Snell-Bergeon JK, McFann K, Wadwa RP, Rewers M, Rivard CJ, Jalal D, Chonchol MB, Johnson RJ, Maahs DM. Serum uric acid and insulin sensitivity in adolescents and adults with and without type 1 diabetes. J Diabetes Complications. 2013 Dec 27. [Epub ahead of print] PubMed PMID: 24461546
  • Lieberman R, Wadwa RP, Nguyen N, Bishop FK, Reinick C, Snell-Bergeon JK, Maahs DM. The association between vitamin D and vascular stiffness in adolescents with and without type 1 diabetes. PLoS One. 2013;8(10):e77272. PubMed PMID: 24204786
  • Dabelea D, Talton JW, D'Agostino R Jr, Wadwa RP, Urbina EM, Dolan LM, Daniels SR, Marcovina SM, Hamman RF. Cardiovascular risk factors are associated with increased arterial stiffness in youth with type 1 diabetes: the SEARCH CVD study. Diabetes Care. 2013 Dec;36(12):3938-43. PubMed PMID: 24101697
  • Jaiswal M, Fingerlin TE, Urbina EM, Wadwa RP, Talton JW, D'Agostino RB Jr, Hamman RF, Daniels SR, Marcovina SM, Dolan LM, Dabelea D. Impact of glycemic control on heart rate variability in youth with type 1 diabetes: the SEARCH CVD study. Diabetes Technol Ther. 2013 Dec;15(12):977-83. PubMed PMID: 24010960
  • Jaiswal M, Urbina EM, Wadwa RP, Talton JW, D'Agostino RB Jr, Hamman RF, Fingerlin TE, Daniels SR, Marcovina SM, Dolan LM, Dabelea D. Reduced heart rate variability is associated with increased arterial stiffness in youth with type 1 diabetes: the SEARCH CVD study. Diabetes Care. 2013 Aug;36(8):2351-8. PubMed PMID: 23435158
  • Jaiswal M, Urbina EM, Wadwa RP, Talton JW, D'Agostino RB Jr, Hamman RF, Fingerlin TE, Daniels S, Marcovina SM, Dolan LM, Dabelea D. Reduced heart rate variability among youth with type 1 diabetes: the SEARCH CVD study. Diabetes Care. 2013 Jan;36(1):157-62. PubMed PMID: 22961570
  • Specht BJ, Wadwa RP, Snell-Bergeon JK, Nadeau KJ, Bishop FK, Maahs DM. Estimated insulin sensitivity and cardiovascular disease risk factors in adolescents with and without type 1 diabetes. J Pediatr. 2013 Feb;162(2):297-301. PubMed PMID: 22921593
  • Maahs DM, Dabelea D, D'Agostino RB Jr, Andrews JS, Shah AS, Crimmins N, Mayer-Davis EJ, Marcovina S, Imperatore G, Wadwa RP, Daniels SR, Reynolds K, Hamman RF, Dolan LM, SEARCH for Diabetes in Youth Study. Glucose control predicts 2-year change in lipid profile in youth with type 1 diabetes. J Pediatr. 2013 Jan;162(1):101-7.e1. PubMed PMID: 22795314
  • Shah AS, Dolan LM, Lauer A, Davis C, Dabelea D, Daniels SR, Hamman RF, Marcovina S, Wadwa RP, Urbina EM. Adiponectin and arterial stiffness in youth with type 1 diabetes: the SEARCH for diabetes in youth study. J Pediatr Endocrinol Metab. 2012;25(7-8):717-21. PubMed PMID: 23155699
  • Bishop FK, Wadwa RP, Ellis S, Rewers M, Maahs DM. Lessons learned from a lipid lowering trial in adolescents with type 1 diabetes. Int J Pediatr Endocrinol. 2012 Jul 30;2012(1):24. PubMed PMID: 22846167
  • Snell-Bergeon JK, Wadwa RP. Hypoglycemia, diabetes, and cardiovascular disease. Diabetes Technol Ther. 2012 Jun;14 Suppl 1:S51-8. PubMed PMID: 22650225
  • Strategies to Enhance New CGM Use in Early Childhood (SENCE) Study Group. A randomized clinical trial assessing continuous glucose monitoring (CGM) use with standardized education with or without a family behavioral intervention compared with fingerstick blood glucose monitoring in very young children with type 1 diabetes. Diabetes Care 2020 (In Press)
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Professional Memberships

  • American Diabetes Association, Member
  • International Society for Pediatric and Adolescent Diabetes, Member

Practice Locations

Barbara Davis Center for Childhood Diabetes - Specialty Clinic
1775 Aurora Ct
Aurora, CO 80045
303-724-2323

Hospital Affiliation
  • Children's Hospital Colorado
  • University of Colorado Hospital
Center Affiliations

Specialty Information

Specialties
  • Pediatric Endocrinology, Board Certification
  • Pediatrics, Board Certification (0001)
  • Pediatric Endocrinology, Board Certification (0001)
Conditions & Treatments
  • Child and Teen Health - Juvenile Diabetes
  • Child and Teen Health
Clinical Interests
Type 1 Diabetes, Clinical trials in type 1 diabetes, Telemedicine, artificial pancreas technology

General Information

Medical Schools:
  • MD, Northwestern University The Feinberg School of Medicine (1996)
Undergraduate Schools:
  • BS, Northwestern University (IL) (1992)
Internships:
  • Nationwide Children's Hospital/Ohio State University Program (1997)
Residency Programs:
  • Nationwide Children's Hospital/Ohio State University Program, Chief Resident, Pediatrics (2000)
Fellowships:
  • Cincinnati Children's Hospital Medical Center Program, Pediatric Endocrinology (2003)
Languages: English
Department: Pediatrics-Barbara Davis Center
;