David Barton, PhD
Professor, Immunology and Microbiology

Publications

• Ancar R, Li Y, Kindler E, Cooper DA, Ransom M, Thiel V, Weiss SR, Hesselberth JR, Barton DJ. Physiologic RNA targets and refined sequence specificity of coronavirus EndoU. RNA. 2020 Dec;26(12):1976-1999. PubMed PMID: 32989044
• Kempf BJ, Watkins CL, Peersen OB, Barton DJ. An Extended Primer Grip of Picornavirus Polymerase Facilitates Sexual RNA Replication Mechanisms. J Virol. 2020 Jul 30;94(16). PubMed PMID: 32522851
• Watkins CL, Kempf BJ, Beaucourt S, Barton DJ, Peersen OB. Picornaviral polymerase domain exchanges reveal a modular basis for distinct biochemical activities of viral RNA-dependent RNA polymerases. J Biol Chem. 2020 Jul 31;295(31):10624-10637. PubMed PMID: 32493771
• Kempf BJ, Watkins CL, Peersen OB, Barton DJ. Picornavirus RNA Recombination Counteracts Error Catastrophe. J Virol. 2019 Jul 15;93(14). PubMed PMID: 31068422
• Kempf BJ, Peersen OB, Barton DJ. Poliovirus Polymerase Leu420 Facilitates RNA Recombination and Ribavirin Resistance. J Virol. 2016 Oct 1;90(19):8410-21. PubMed PMID: 27412593
• Cooper DA, Banerjee S, Chakrabarti A, García-Sastre A, Hesselberth JR, Silverman RH, Barton DJ. RNase L Targets Distinct Sites in Influenza A Virus RNAs. J Virol. 2015 Mar 1;89(5):2764-76. PubMed PMID: 25540362
• Kempf BJ, Barton DJ. Picornavirus RNA polyadenylation by 3D(pol), the viral RNA-dependent RNA polymerase. Virus Res. 2015 Aug 3;206:3-11. PubMed PMID: 25559071
• Cooper DA, Banerjee S, Chakrabarti A, García-Sastre A, Hesselberth JR, Silverman RH, Barton DJ. RNase L targets distinct sites in influenza A virus RNAs. J Virol. 2015 Mar;89(5):2764-76. PubMed PMID: 25540362
• Kempf BJ, Barton DJ. Picornavirus RNA polyadenylation by 3D(pol), the viral RNA-dependent RNA polymerase. Virus Res. 2015 Jan 3. [Epub ahead of print] PubMed PMID: 25559071
• Cooper DA, Jha BK, Silverman RH, Hesselberth JR, Barton DJ. Ribonuclease L and metal-ion-independent endoribonuclease cleavage sites in host and viral RNAs. Nucleic Acids Res. 2014 Feb 5. [Epub ahead of print] PubMed PMID: 24500209
• Cooper DA, Jha BK, Silverman RH, Hesselberth JR, Barton DJ. Ribonuclease L and metal-ion-independent endoribonuclease cleavage sites in host and viral RNAs. Nucleic Acids Res. 2014 Apr;42(8):5202-16. PubMed PMID: 24500209
• Kempf BJ, Kelly MM, Springer CL, Peersen OB, Barton DJ. Structural features of a picornavirus polymerase involved in the polyadenylation of viral RNA. J Virol. 2013 May;87(10):5629-44. PubMed PMID: 23468507