Lee Niswander, PhD
Associate Professor, University of Colorado - Boulder

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Graduate School :
  • MPT, University of Colorado Denver (1986)
Languages: English
Department: University of Colorado - Boulder

Publications

  • Zhang L, Ferreyros M, Feng W, Hupe M, Crumrine DA, Chen J, Elias PM, Holleran WM, Niswander L, Hohl D, Williams T, Torchia EC, Roop DR. Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis. PLoS One. 2016 Aug 23;11(8):e0161465. PubMed PMID: 27551807
  • Ray HJ, Niswander LA. Dynamic behaviors of the non-neural ectoderm during mammalian cranial neural tube closure. Dev Biol. 2016 Aug 15;416(2):279-85. PubMed PMID: 27343896
  • Ray HJ, Niswander LA. Grainyhead-like 2 downstream targets act to suppress epithelial-to-mesenchymal transition during neural tube closure. Development. 2016 Apr 1;143(7):1192-204. PubMed PMID: 26903501
  • Van Otterloo E, Feng W, Jones KL, Hynes NE, Clouthier DE, Niswander L, Williams T. MEMO1 drives cranial endochondral ossification and palatogenesis. Dev Biol. 2016 Jul 15;415(2):278-95. PubMed PMID: 26746790
  • Gartz Hanson M, Aiken J, Sietsema DV, Sept D, Bates EA, Niswander L, Moore JK. Novel a-tubulin mutation disrupts neural development and tubulin proteostasis. Dev Biol. 2016 Jan 15;409(2):406-19. PubMed PMID: 26658218
  • Hanson MG, Wilde JJ, Moreno RL, Minic AD, Niswander L. Potassium dependent rescue of a myopathy with core-like structures in mouse. Elife. 2015 Jan 7;4. [Epub ahead of print] PubMed PMID: 25564733
  • Gartz Hanson M, Niswander LA. Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos. Dev Biol. 2015 Aug 15;404(2):76-87. PubMed PMID: 26025922
  • Yang M, Yang SL, Herrlinger S, Liang C, Dzieciatkowska M, Hansen KC, Desai R, Nagy A, Niswander L, Moss EG, Chen JF. Lin28 promotes the proliferative capacity of neural progenitor cells in brain development. Development. 2015 May 1;142(9):1616-27. PubMed PMID: 25922525
  • Chang R, Petersen JR, Niswander LA, Liu A. A hypomorphic allele reveals an important role of inturned in mouse skeletal development. Dev Dyn. 2015 Jun;244(6):736-47. PubMed PMID: 25774014
  • Hanson MG, Wilde JJ, Moreno RL, Minic AD, Niswander L. Potassium dependent rescue of a myopathy with core-like structures in mouse. Elife. 2015 Jan 7;4. PubMed PMID: 25564733
  • Wilde JJ, Petersen JR, Niswander L. Genetic, epigenetic, and environmental contributions to neural tube closure. Annu Rev Genet. 2014;48:583-611. PubMed PMID: 25292356
  • Hanson MG, Niswander LA. An explant muscle model to examine the refinement of the synaptic landscape. J Neurosci Methods. 2014 Dec 30;238:95-104. PubMed PMID: 25251554
  • Hanson MG, Fregoso VL, Vrana JD, Tucker CL, Niswander LA. Peripheral nervous system defects in a mouse model for peroxisomal biogenesis disorders. Dev Biol. 2014 Nov 1;395(1):84-95. PubMed PMID: 25176044
  • Apkon SD, Grady R, Hart S, Lee A, McNalley T, Niswander L, Petersen J, Remley S, Rotenstein D, Shurtleff H, Warner M, Walker WO Jr. Advances in the care of children with spina bifida. Adv Pediatr. 2014 Aug;61(1):33-74. PubMed PMID: 25037124
  • Sussel L, Niswander L. Editorial overview: developmental mechanisms, patterning and evolution. Curr Opin Genet Dev. 2014 Aug;27:v-vii. PubMed PMID: 24998023
  • Massarwa R, Ray HJ, Niswander L. Morphogenetic movements in the neural plate and neural tube: mouse. Wiley Interdiscip Rev Dev Biol. 2014 Jan-Feb;3(1):59-68. PubMed PMID: 24902834
  • Chen JF, Zhang Y, Wilde J, Hansen KC, Lai F, Niswander L. Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size. Nat Commun. 2014 May 30;5:3885. PubMed PMID: 24875059
  • Harmacek L, Watkins-Chow DE, Chen J, Jones KL, Pavan WJ, Salbaum JM, Niswander L. A unique missense allele of BAF155, a core BAF chromatin remodeling complex protein, causes neural tube closure defects in mice. Dev Neurobiol. 2014 May;74(5):483-97. PubMed PMID: 24170322
  • Wilde JJ, Petersen JR, Niswander L. Genetic, epigenetic, and environmental contributions to neural tube closure. Annu Rev Genet. 2014;48:583-611. PubMed PMID: 25292356
  • Hanson MG, Niswander LA. An explant muscle model to examine the refinement of the synaptic landscape. J Neurosci Methods. 2014 Dec 30;238:95-104. PubMed PMID: 25251554
  • Hanson MG, Fregoso VL, Vrana JD, Tucker CL, Niswander LA. Peripheral nervous system defects in a mouse model for peroxisomal biogenesis disorders. Dev Biol. 2014 Nov 1;395(1):84-95. PubMed PMID: 25176044
  • Apkon SD, Grady R, Hart S, Lee A, McNalley T, Niswander L, Petersen J, Remley S, Rotenstein D, Shurtleff H, Warner M, Walker WO Jr. Advances in the care of children with spina bifida. Adv Pediatr. 2014 Aug;61(1):33-74. PubMed PMID: 25037124
  • Sussel L, Niswander L. Editorial overview: developmental mechanisms, patterning and evolution. Curr Opin Genet Dev. 2014 Aug;27:v-vii. PubMed PMID: 24998023
  • Massarwa R, Ray HJ, Niswander L. Morphogenetic movements in the neural plate and neural tube: mouse. Wiley Interdiscip Rev Dev Biol. 2014 Jan-Feb;3(1):59-68. PubMed PMID: 24902834
  • Chen JF, Zhang Y, Wilde J, Hansen KC, Lai F, Niswander L. Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size. Nat Commun. 2014 May 30;5:3885. PubMed PMID: 24875059
  • Harmacek L, Watkins-Chow DE, Chen J, Jones KL, Pavan WJ, Salbaum JM, Niswander L. A unique missense allele of BAF155, a core BAF chromatin remodeling complex protein, causes neural tube closure defects in mice. Dev Neurobiol. 2014 May;74(5):483-97. PubMed PMID: 24170322
  • Yates LL, Schnatwinkel C, Hazelwood L, Chessum L, Paudyal A, Hilton H, Romero MR, Wilde J, Bogani D, Sanderson J, Formstone C, Murdoch JN, Niswander LA, Greenfield A, Dean CH. Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung. Dev Biol. 2013 Jan 15;373(2):267-80. PubMed PMID: 23195221
  • Massarwa R, Niswander L. In toto live imaging of mouse morphogenesis and new insights into neural tube closure. Development. 2013 Jan 1;140(1):226-36. PubMed PMID: 23175632
  • Parker JJ, Dionne KR, Massarwa R, Klaassen M, Foreman NK, Niswander L, Canoll P, Kleinschmidt-Demasters BK, Waziri A. Gefitinib selectively inhibits tumor cell migration in EGFR-amplified human glioblastoma. Neuro Oncol. 2013 Aug;15(8):1048-57. PubMed PMID: 23749785
  • Wallingford JB, Niswander LA, Shaw GM, Finnell RH. The continuing challenge of understanding, preventing, and treating neural tube defects. Science. 2013 Mar 1;339(6123):1222002. PubMed PMID: 23449594
  • Yates LL, Schnatwinkel C, Hazelwood L, Chessum L, Paudyal A, Hilton H, Romero MR, Wilde J, Bogani D, Sanderson J, Formstone C, Murdoch JN, Niswander LA, Greenfield A, Dean CH. Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung. Dev Biol. 2013 Jan 15;373(2):267-80. PubMed PMID: 23195221
  • McKean DM, Niswander L. Defects in GPI biosynthesis perturb Cripto signaling during forebrain development in two new mouse models of holoprosencephaly. Biol Open. 2012 Sep 15;1(9):874-83. PubMed PMID: 23213481
  • Zhang Y, Niswander L. Phactr4: a new integrin modulator required for directional migration of enteric neural crest cells. Cell Adh Migr. 2012 Sep-Oct;6(5):419-23. PubMed PMID: 23076051
  • Schnatwinkel C, Niswander L. Nubp1 is required for lung branching morphogenesis and distal progenitor cell survival in mice. PLoS One. 2012;7(9):e44871. PubMed PMID: 23028652
  • Ray HJ, Niswander L. Mechanisms of tissue fusion during development. Development. 2012 May;139(10):1701-11. PubMed PMID: 22510983
  • Chen J, Lai F, Niswander L. The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling. Genes Dev. 2012 Apr 15;26(8):803-15. PubMed PMID: 22508726
  • Zhang Y, Kim TH, Niswander L. Phactr4 regulates directional migration of enteric neural crest through PP1, integrin signaling, and cofilin activity. Genes Dev. 2012 Jan 1;26(1):69-81. PubMed PMID: 22215812
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Practice Locations

Hospital Affiliation
  • Children's Hospital Colorado

General Information

Graduate Schools:
  • MPT, University of Colorado Denver (1986)
Languages: English
Department: University of Colorado - Boulder
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