Jing Wang, PhD
Associate Professor, Immunology and Microbiology

Publications

  • Wang X, Waschke BC, Woolaver RA, Chen SMY, Chen Z, Wang JH. MHC class I-independent activation of virtual memory CD8 T cells induced by chemotherapeutic agent-treated cancer cells. Cell Mol Immunol. 2020 May 19. [Epub ahead of print] PubMed PMID: 32427883
  • Chen Z, Krinsky A, Woolaver RA, Wang X, Chen SMY, Popolizio V, Xie P, Wang JH. TRAF3 Acts as a Checkpoint of B Cell Receptor Signaling to Control Antibody Class Switch Recombination and Anergy. J Immunol. 2020 Aug 1;205(3):830-841. PubMed PMID: 32591397
  • Chen SMY, Li B, Nicklawsky AG, Krinsky AL, Brunetti T, Woolaver RA, Wang X, Chen Z, Young CD, Gao D, Wang XJ, Wang JH. Deletion of p53 and Hyper-Activation of PIK3CA in Keratin-15( ) Stem Cells Lead to the Development of Spontaneous Squamous Cell Carcinoma. Int J Mol Sci. 2020 Sep 9;21(18). PubMed PMID: 32916850
  • Morton JJ, Alzofon N, Keysar SB, Chimed TS, Reisinger J, Perrenoud L, Le PN, Nieto C, Gomez K, Miller B, Yeager R, Gao D, Tan AC, Somerset H, Medina T, Wang XJ, Wang JH, Robinson W, Roop DR, Gonzalez R, Jimeno A. Studying Immunotherapy Resistance in a Melanoma Autologous Humanized Mouse Xenograft. Mol Cancer Res. 2020 Oct 21. [Epub ahead of print] PubMed PMID: 33087417
  • Wang X, Waschke BC, Woolaver RA, Chen SMY, Chen Z, Wang JH. HDAC inhibitors overcome immunotherapy resistance in B-cell lymphoma. Protein Cell. 2020 Jul;11(7):472-482. PubMed PMID: 32162275
  • Chen SMY, Krinsky AL, Woolaver RA, Wang X, Chen Z, Wang JH. Tumor immune microenvironment in head and neck cancers. Mol Carcinog. 2020 Jul;59(7):766-774. PubMed PMID: 32017286
  • Wang JH. Why the Outcome of Anti-Tumor Immune Responses is Heterogeneous: A Novel Idea in the Context of Immunological Heterogeneity in Cancers. Bioessays. 2020 Oct;42(10):e2000024. PubMed PMID: 32767371
  • Wu FL, Nolan K, Strait AA, Bian L, Nguyen KA, Wang JH, Jimeno A, Zhou HM, Young CD, Wang XJ. Macrophages Promote Growth of Squamous Cancer Independent of T cells. J Dent Res. 2019 Jul;98(8):896-903. PubMed PMID: 31189369
  • Wang X, Waschke BC, Woolaver RA, Chen Z, Zhang G, Piscopio AD, Liu X, Wang JH. Histone Deacetylase Inhibition Sensitizes PD1 Blockade-Resistant B-cell Lymphomas. Cancer Immunol Res. 2019 Aug;7(8):1318-1331. PubMed PMID: 31235619
  • Chen Z, Wang JH. Signaling control of antibody isotype switching. Adv Immunol. 2019;141:105-164. PubMed PMID: 30904131
  • Hernandez AL, Young CD, Wang JH, Wang XJ. Lessons learned from SMAD4 loss in squamous cell carcinomas. Mol Carcinog. 2019 Sep;58(9):1648-1655. PubMed PMID: 31140647
  • Wang X, Chen Z, Mishra AK, Silva A, Ren W, Pan Z, Wang JH. Chemotherapy-induced differential cell cycle arrest in B-cell lymphomas affects their sensitivity to Wee1 inhibition. Haematologica. 2018 Mar;103(3):466-476. PubMed PMID: 29217775
  • Woolaver RA, Wang X, Dollin Y, Xie P, Wang JH, Chen Z. TRAF2 Deficiency in B Cells Impairs CD40-Induced Isotype Switching That Can Be Rescued by Restoring NF-?B1 Activation. J Immunol. 2018 Dec 1;201(11):3421-3430. PubMed PMID: 30341187
  • Wang X, Chen Z, Mishra AK, Silva A, Ren W, Pan Z, Wang JH. Chemotherapy-induced differential cell cycle arrest in B cell lymphomas affects their sensitivity to Wee1 inhibition. Haematologica. 2017 Dec 7. [Epub ahead of print] PubMed PMID: 29217775
  • Chen Z, Elos MT, Viboolsittiseri SS, Gowan K, Leach SM, Rice M, Eder MD, Jones K, Wang JH. Combined deletion of Xrcc4 and Trp53 in mouse germinal center B cells leads to novel B cell lymphomas with clonal heterogeneity. J Hematol Oncol. 2016 Jan 7;9(1):2. PubMed PMID: 26740101
  • Mishra AK, Kadoishi T, Wang X, Driver E, Chen Z, Wang XJ, Wang JH. Squamous cell carcinomas escape immune surveillance via inducing chronic activation and exhaustion of CD8 T Cells co-expressing PD-1 and LAG-3 inhibitory receptors. Oncotarget. 2016 Dec 6;7(49):81341-81356. PubMed PMID: 27835902
  • Chen Z, Gowan K, Leach SM, Viboolsittiseri SS, Mishra AK, Kadoishi T, Diener K, Gao B, Jones K, Wang JH. Unexpected effects of different genetic backgrounds on identification of genomic rearrangements via whole-genome next generation sequencing. BMC Genomics. 2016 Oct 21;17(1):823. PubMed PMID: 27769169
  • Chen Z, Eder MD, Elos MT, Viboolsittiseri SS, Chen X, Wang JH. Interplay between Target Sequences and Repair Pathways Determines Distinct Outcomes of AID-Initiated Lesions. J Immunol. 2016 Mar 1;196(5):2335-47. PubMed PMID: 26810227
  • Chen Z, Elos MT, Viboolsittiseri SS, Gowan K, Leach SM, Rice M, Eder MD, Jones K, Wang JH. Combined deletion of Xrcc4 and Trp53 in mouse germinal center B cells leads to novel B cell lymphomas with clonal heterogeneity. J Hematol Oncol. 2016 Jan 7;9:2. PubMed PMID: 26740101
  • Chen Z, Getahun A, Chen X, Dollin Y, Cambier JC, Wang JH. Imbalanced PTEN and PI3K Signaling Impairs Class Switch Recombination. J Immunol. 2015 Dec 1;195(11):5461-71. PubMed PMID: 26500350
  • Yeap LS, Hwang JK, Du Z, Meyers RM, Meng FL, Jakubauskaite A, Liu M, Mani V, Neuberg D, Kepler TB, Wang JH, Alt FW. Sequence-Intrinsic Mechanisms that Target AID Mutational Outcomes on Antibody Genes. Cell. 2015 Nov 19;163(5):1124-37. PubMed PMID: 26582132
  • Lu Y, Wu Y, Feng X, Shen R, Wang JH, Fallahi M, Li W, Yang C, Hankey W, Zhao W, Ganju RK, Li MO, Cleveland JL, Zou X. CDK4 deficiency promotes genomic instability and enhances Myc-driven lymphomagenesis. J Clin Invest. 2014 Apr;124(4):1672-84. PubMed PMID: 24614102
  • Chen Z, Ranganath S, Viboolsittiseri SS, Eder MD, Chen X, Elos MT, Yuan S, Hansen E, Wang JH. AID-initiated DNA lesions are differentially processed in distinct B cell populations. J Immunol. 2014 Dec 1;193(11):5545-56. PubMed PMID: 25339658
  • Chen Z, Wang JH. Generation and repair of AID-initiated DNA lesions in B lymphocytes. Front Med. 2014 Jun;8(2):201-16. PubMed PMID: 24748462
View All (24 Total) View Less

General Information

Department: Immunology and Microbiology
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