Randall Cohrs, PhD, MS
Research Professor, Neurology

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Department: Neurology

Publications

  • Rovnak J, St Clair LA, McAlister C, Ogbu CP, Smolenske J, Cohrs RJ, Perera R. The 20th Anniversary Meeting of the Rocky Mountain Virology Association. Viruses. 2020 Dec 29;13(1). PubMed PMID: 33383821
  • Bubak AN, Beseler C, Como CN, Coughlan CM, Johnson NR, Hassell JE, Burnet AM, Mescher T, Schmid DS, Coleman C, Mahalingam R, Cohrs RJ, Boyd TD, Potter H, Shilleh AH, Russ HA, Nagel MA. Amylin, Aß42, and Amyloid in VZV Vasculopathy Cerebrospinal Fluid and Infected Vascular Cells. J Infect Dis. 2020 Aug 18. [Epub ahead of print] PubMed PMID: 32809013
  • Ramachandran V, Elliott SC, Rogers KL, Cohrs RJ, Weinberger M, Jackson W, Carpenter JE, Grose C, Bonthius DJ. Varicella Vaccine Meningitis as a Complication of Herpes Zoster in Twice-Immunized Immunocompetent Adolescents. J Child Neurol. 2020 Nov;35(13):889-895. PubMed PMID: 32677551
  • Bubak AN, Beseler C, Como CN, Tyring SK, Haley C, Mescher T, Hassell JE Jr, Cohrs RJ, Potter H, Nagel MA. Acute zoster plasma contains elevated amyloid, correlating with Aß42 and amylin levels, and is amyloidogenic. J Neurovirol. 2020 Jun;26(3):422-428. PubMed PMID: 32385803
  • Rovnak J, St Clair LA, Lian E, McAlister C, Perera R, Cohrs RJ. The 19th Rocky Mountain Virology Association Meeting. Viruses. 2020 Jan 11;12(1). PubMed PMID: 31940824
  • Bubak AN, Como CN, Coughlan CM, Johnson NR, Hassell JE, Mescher T, Niemeyer CS, Mahalingam R, Cohrs RJ, Boyd TD, Potter H, Russ HA, Nagel MA. Varicella-Zoster Virus Infection of Primary Human Spinal Astrocytes Produces Intracellular Amylin, Amyloid-ß, and an Amyloidogenic Extracellular Environment. J Infect Dis. 2020 Mar 16;221(7):1088-1097. PubMed PMID: 31665341
  • Mangold CA, Engel EA, Ostler JB Jr, Wilson AC, Cohrs RJ. 2019 Colorado Alphaherpesvirus Latency Society symposium. J Neurovirol. 2020 Apr;26(2):297-309. PubMed PMID: 31502208
  • Rovnak J, Clair LAS, Krieger K, Lian E, Perera R, Cohrs RJ. The 18th Rocky Mountain Virology Association Meeting. Viruses. 2018 Dec 21;11(1). PubMed PMID: 30577629
  • Baird NL, Depledge DP, Cohrs RJ. 2018 Colorado Alphaherpesvirus Latency Society Symposium. J Neurovirol. 2018 Dec;24(6):797-812. PubMed PMID: 30414047
  • Como CN, Pearce CM, Cohrs RJ, Baird NL. Interleukin-6 and type 1 interferons inhibit varicella zoster virus replication in human neurons. Virology. 2018 Sep;522:13-18. PubMed PMID: 29979960
  • Bubak AN, Como CN, Blackmon AM, Frietze S, Mescher T, Jones D, Cohrs RJ, Paucek P, Baird NL, Nagel MA. Varicella Zoster Virus Induces Nuclear Translocation of the Neurokinin-1 Receptor, Promoting Lamellipodia Formation and Viral Spread in Spinal Astrocytes. J Infect Dis. 2018 Sep 8;218(8):1324-1335. PubMed PMID: 29788447
  • Depledge DP, Ouwendijk WJD, Sadaoka T, Braspenning SE, Mori Y, Cohrs RJ, Verjans GMGM, Breuer J. A spliced latency-associated VZV transcript maps antisense to the viral transactivator gene 61. Nat Commun. 2018 Mar 21;9(1):1167. PubMed PMID: 29563516
  • Rovnak J, Perera R, Hopken MW, Read J, Waller DM, Cohrs RJ. The 17th Rocky Mountain Virology Association Meeting. Viruses. 2017 Nov 8;9(11). PubMed PMID: 29117106
  • Baird NL, Cohrs RJ. Erratum to: 2017 Colorado alphaherpesvirus latency society symposium. J Neurovirol. 2017 Oct;23(5):793. PubMed PMID: 28963639
  • Baird NL, Cohrs RJ. 2017 Colorado alphaherpesvirus latency society symposium. J Neurovirol. 2017 Aug;23(4):642-655. PubMed PMID: 28786028
  • Cohrs RJ, Lee KS, Beach A, Sanford B, Baird NL, Como C, Graybill C, Jones D, Tekeste E, Ballard M, Chen X, Yalacki D, Frietze S, Jones K, Lenac Rovis T, Jonjic S, Haas J, Gilden D. Targeted Genome Sequencing Reveals Varicella-Zoster Virus Open Reading Frame 12 Deletion. J Virol. 2017 Oct 15;91(20). PubMed PMID: 28747504
  • Owens GP, Nagel MA, Mahalingam R, Cohrs RJ. Donald H. Gilden, M.D. J Neuroimmunol. 2017 Jul 15;308:2-5. PubMed PMID: 28087078
  • Cohrs RJ, Badani H, Baird NL, White TM, Sanford B, Gilden D. Induction of varicella zoster virus DNA replication in dissociated human trigeminal ganglia. J Neurovirol. 2017 Feb;23(1):152-157. PubMed PMID: 27683235
  • Cohrs RJ, Badani H, Baird NL, White TM, Sanford B, Gilden D. Induction of varicella zoster virus DNA replication in dissociated human trigeminal ganglia. J Neurovirol. 2016 Sep 28. [Epub ahead of print] PubMed PMID: 27683235
  • Gilden D, Grose C, White T, Nagae L, Hendricks RL, Cohrs RJ, Nagel MA. Successful antiviral treatment after 6years of chronic progressive neurological disease attributed to VZV brain infection. J Neurol Sci. 2016 Sep 15;368:240-2. PubMed PMID: 27538641
  • Cohrs RJ, Gilden D. 2016 Colorado alphaherpesvirus latency society symposium. J Neurovirol. 2016 Oct;22(5):703-714. PubMed PMID: 27405986
  • Biswas K, Chatterjee D, Addya S, Khan RS, Kenyon LC, Choe A, Cohrs RJ, Shindler KS, Das Sarma J. Demyelinating strain of mouse hepatitis virus infection bridging innate and adaptive immune response in the induction of demyelination. Clin Immunol. 2016 Sep;170:9-19. PubMed PMID: 27394164
  • Keller AC, Badani H, McClatchey PM, Baird NL, Bowlin JL, Bouchard R, Perng GC, Reusch JE, Kaufer BB, Gilden D, Shahzad A, Kennedy PG, Cohrs RJ. Varicella zoster virus infection of human fetal lung cells alters mitochondrial morphology. J Neurovirol. 2016 Oct;22(5):674-682. PubMed PMID: 27245593
  • Cohrs RJ, Badani H, Bos N, Scianna C, Hoskins I, Baird NL, Gilden D. Alphaherpesvirus DNA replication in dissociated human trigeminal ganglia. J Neurovirol. 2016 Oct;22(5):688-694. PubMed PMID: 27173396
  • Henderson HH, Timberlake KB, Austin ZA, Badani H, Sanford B, Tremblay K, Baird NL, Jones K, Rovnak J, Frietze S, Gilden D, Cohrs RJ. Occupancy of RNA Polymerase II Phosphorylated on Serine 5 (RNAP S5P) and RNAP S2P on Varicella-Zoster Virus Genes 9, 51, and 66 Is Independent of Transcript Abundance and Polymerase Location within the Gene. J Virol. 2015 Nov 11;90(3):1231-43. PubMed PMID: 26559844
  • Cohrs RJ, Gilden D. 2015 Colorado Alphaherpesvirus Latency Society Symposium. J Neurovirol. 2015 Dec;21(6):706-16. PubMed PMID: 26506840
  • Shahzad A, Gilden D, Cohrs RJ. Translational medicine and varicella zoster virus: need for disease modeling. New Horiz Transl Med. 2015 Mar 1;2(3):89-91. PubMed PMID: 26086038
  • Goodwin TJ, McCarthy M, Cohrs RJ, Kaufer BB. 3D tissue-like assemblies: A novel approach to investigate virus-cell interactions. Methods. 2015 Nov 15;90:76-84. PubMed PMID: 25986169
  • Baird NL, Bowlin JL, Hotz TJ, Cohrs RJ, Gilden D. Interferon Gamma Prolongs Survival of Varicella-Zoster Virus-Infected Human Neurons In Vitro. J Virol. 2015 Jul;89(14):7425-7. PubMed PMID: 25948748
  • Kennedy PG, Rovnak J, Badani H, Cohrs RJ. A comparison of herpes simplex virus type 1 and varicella-zoster virus latency and reactivation. J Gen Virol. 2015 Jul;96(Pt 7):1581-602. PubMed PMID: 25794504
  • Gilden D, White T, Khmeleva N, Heintzman A, Choe A, Boyer PJ, Grose C, Carpenter JE, Rempel A, Bos N, Kandasamy B, Lear-Kaul K, Holmes DB, Bennett JL, Cohrs RJ, Mahalingam R, Mandava N, Eberhart CG, Bockelman B, Poppiti RJ, Tamhankar MA, Fogt F, Amato M, Wood E, Durairaj V, Rasmussen S, Petursdottir V, Pollak L, Mendlovic S, Chatelain D, Keyvani K, Brueck W, Nagel MA. Prevalence and distribution of VZV in temporal arteries of patients with giant cell arteritis. Neurology. 2015 May 12;84(19):1948-55. PubMed PMID: 25695965
  • Pollak L, Mehta SK, Pierson DL, Sacagiu T, Avneri Kalmanovich S, Cohrs RJ. Varicella-zoster DNA in saliva of patients with meningoencephalitis: a preliminary study. Acta Neurol Scand. 2015 Jun;131(6):417-21. PubMed PMID: 25314141
  • Sabry A, Hauk PJ, Jing H, Su HC, Stence NV, Mirsky DM, Nagel MA, Abbott JK, Dragone LL, Armstrong-Wells J, Curtis DJ, Cohrs R, Schmid DS, Gilden D, Gelfand EW. Vaccine strain varicella-zoster virus-induced central nervous system vasculopathy as the presenting feature of DOCK8 deficiency. J Allergy Clin Immunol. 2014 Jan 10. [Epub ahead of print] PubMed PMID: 24418481
  • Birlea M, Cohrs RJ, Bos N, Mehta SK, Pierson DL, Gilden D. Search for varicella zoster virus DNA in saliva of healthy individuals aged 20-59 years. J Med Virol. 2014 Feb;86(2):360-2. PubMed PMID: 24338812
  • Birlea M, Nagel MA, Khmeleva N, Choe A, Kleinschmidt-Demasters B, Hevner R, Boyer P, Lear-Kaul KC, Bos N, Wellish M, Cohrs RJ, Gilden D. Varicella-zoster virus trigeminal ganglioneuritis without rash. Neurology. 2014 Jan 7;82(1):90-2. PubMed PMID: 24285619
  • Cohrs RJ, Gilden D. 2014 Colorado alphaherpesvirus latency symposium. J Neurovirol. 2014 Dec;20(6):644-56. PubMed PMID: 25371285
  • Chatterjee D, Addya S, Khan RS, Kenyon LC, Choe A, Cohrs RJ, Shindler KS, Sarma JD. Mouse hepatitis virus infection upregulates genes involved in innate immune responses. PLoS One. 2014;9(10):e111351. PubMed PMID: 25360880
  • Pollak L, Mehta SK, Pierson DL, Sacagiu T, Avneri Kalmanovich S, Cohrs RJ. Varicella-zoster DNA in saliva of patients with meningoencephalitis: a preliminary study. Acta Neurol Scand. 2014 Oct 14. [Epub ahead of print] PubMed PMID: 25314141
  • Gilden D, Nagel MA, Cohrs RJ. Varicella-zoster. Handb Clin Neurol. 2014;123:265-83. PubMed PMID: 25015490
  • Baird NL, Bowlin JL, Yu X, Jonjic S, Haas J, Cohrs RJ, Gilden D. Varicella zoster virus DNA does not accumulate in infected human neurons. Virology. 2014 Jun;458-459:1-3. PubMed PMID: 24928033
  • Baird NL, Bowlin JL, Cohrs RJ, Gilden D, Jones KL. Comparison of varicella-zoster virus RNA sequences in human neurons and fibroblasts. J Virol. 2014 May;88(10):5877-80. PubMed PMID: 24600007
  • Sabry A, Hauk PJ, Jing H, Su HC, Stence NV, Mirsky DM, Nagel MA, Abbott JK, Dragone LL, Armstrong-Wells J, Curtis DJ, Cohrs R, Schmid DS, Gilden D, Gelfand EW. Vaccine strain varicella-zoster virus-induced central nervous system vasculopathy as the presenting feature of DOCK8 deficiency. J Allergy Clin Immunol. 2014 Apr;133(4):1225-7. PubMed PMID: 24418481
  • Birlea M, Cohrs RJ, Bos N, Mehta SK, Pierson DL, Gilden D. Search for varicella zoster virus DNA in saliva of healthy individuals aged 20-59 years. J Med Virol. 2014 Feb;86(2):360-2. PubMed PMID: 24338812
  • Birlea M, Nagel MA, Khmeleva N, Choe A, Kleinschmidt-Demasters B, Hevner R, Boyer P, Lear-Kaul KC, Bos N, Wellish M, Cohrs RJ, Gilden D. Varicella-zoster virus trigeminal ganglioneuritis without rash. Neurology. 2014 Jan 7;82(1):90-2. PubMed PMID: 24285619
  • Cohrs RJ, Gilden D. 2013 Colorado alphaherpesvirus latency symposium. J Neurovirol. 2013 Dec;19(6):610-7. PubMed PMID: 24092643
  • Baird NL, Yu X, Cohrs RJ, Gilden D. Varicella zoster virus (VZV)-human neuron interaction. Viruses. 2013 Sep 4;5(9):2106-15. PubMed PMID: 24008377
  • Mueller NH, Gilden D, Cohrs RJ. Varicella-zoster virus open reading frame 48 encodes an active nuclease. J Virol. 2013 Nov;87(21):11936-8. PubMed PMID: 23966396
  • Goodwin TJ, McCarthy M, Osterrieder N, Cohrs RJ, Kaufer BB. Three-dimensional normal human neural progenitor tissue-like assemblies: a model of persistent varicella-zoster virus infection. PLoS Pathog. 2013;9(8):e1003512. PubMed PMID: 23935496
  • Gilden D, Nagel MA, Cohrs RJ, Mahalingam R. The variegate neurological manifestations of varicella zoster virus infection. Curr Neurol Neurosci Rep. 2013 Sep;13(9):374. PubMed PMID: 23884722
  • Grose C, Yu X, Cohrs RJ, Carpenter JE, Bowlin JL, Gilden D. Aberrant virion assembly and limited glycoprotein C production in varicella-zoster virus-infected neurons. J Virol. 2013 Sep;87(17):9643-8. PubMed PMID: 23804641
  • Nagel MA, Choe A, Gilden D, Traina-Dorge V, Cohrs RJ, Mahalingam R. GeXPS multiplex PCR analysis of the simian varicella virus transcriptome in productively infected cells in culture and acutely infected ganglia. J Virol Methods. 2013 Oct;193(1):151-8. PubMed PMID: 23769859
  • Mehta SK, Tyring SK, Cohrs RJ, Gilden D, Feiveson AH, Lechler KJ, Pierson DL. Rapid and sensitive detection of varicella zoster virus in saliva of patients with herpes zoster. J Virol Methods. 2013 Oct;193(1):128-30. PubMed PMID: 23747545
  • Yu X, Seitz S, Pointon T, Bowlin JL, Cohrs RJ, Jonjic S, Haas J, Wellish M, Gilden D. Varicella zoster virus infection of highly pure terminally differentiated human neurons. J Neurovirol. 2013 Feb;19(1):75-81. PubMed PMID: 23233078
  • Birlea M, Owens GP, Eshleman EM, Ritchie A, Traktinskiy I, Bos N, Seitz S, Azarkh Y, Mahalingam R, Gilden D, Cohrs RJ. Human anti-varicella-zoster virus (VZV) recombinant monoclonal antibody produced after Zostavax immunization recognizes the gH/gL complex and neutralizes VZV infection. J Virol. 2013 Jan;87(1):415-21. PubMed PMID: 23077312
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General Information

Department: Neurology
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