Daniel Ambruso, MD
Clinical Professor, Pediatrics

Research Interests

Teaching

Publications

• McKinney CM, Siringo F, Olson JL, Capocelli KE, Ambruso DR, Nuss R. Red cell exchange transfusion halts progressive proliferative sickle cell retinopathy in a teenaged patient with hemoglobin SC disease. Pediatr Blood Cancer. 2015 Apr;62(4):721-3. PubMed PMID: 25631233
• Ballen KK, Logan BR, Laughlin MJ, He W, Ambruso DR, Armitage SE, Beddard RL, Bhatla D, Hwang WY, Kiss JE, Koegler G, Kurtzberg J, Nagler A, Oh D, Petz LD, Price TH, Quinones RR, Ratanatharathorn V, Rizzo JD, Sazama K, Scaradavou A, Schuster MW, Sender LS, Shpall EJ, Spellman SR, Sutton M, Weitekamp LA, Wingard JR, Eapen M. Effect of cord blood processing on transplantation outcomes after single myeloablative umbilical cord blood transplantation. Biol Blood Marrow Transplant. 2015 Apr;21(4):688-95. PubMed PMID: 25543094
• Ballen KK, Logan BR, Laughlin MJ, He W, Ambruso DR, Armitage SE, Beddard RL, Bhatla D, Hwang WY, Kiss JE, Koegler G, Kurtzberg J, Nagler A, Oh D, Petz LD, Price TH, Quinones RR, Ratanatharathorn V, Rizzo JD, Sazama K, Scaradavou A, Schuster MW, Sender LS, Shpall EJ, Spellman SR, Sutton M, Weitekamp LA, Wingard JR, Eapen M. Effect of Cord Blood Processing on Transplantation Outcomes after Single Myeloablative Umbilical Cord Blood Transplantation. Biol Blood Marrow Transplant. 2014 Dec 24. [Epub ahead of print] PubMed PMID: 25543094
• Cancelas JA, Padmanabhan A, Le T, Ambruso DR, Rugg N, Worsham DN, Pinkard SL, Graminske S, Buck J, Goldberg J, Bill J. Spectra Optia granulocyte apheresis collections result in higher collection efficiency of viable, functional neutrophils in a randomized, crossover, multicenter trial. Transfusion. 2014 Nov 10. [Epub ahead of print] PubMed PMID: 25382805
• Ambruso DR. Hydroxyethyl starch and granulocyte transfusions: considerations of utility and toxicity profile for patients and donors. Transfusion. 2014 Oct 15. [Epub ahead of print] PubMed PMID: 25315227
• Josephson CD, Mondoro TH, Ambruso DR, Sanchez R, Sloan SR, Luban NL, Widness JA. One size will never fit all: the future of research in pediatric transfusion medicine. Pediatr Res. 2014 Nov;76(5):425-31. PubMed PMID: 25119336
• Ambruso DR. Transfusion complications in thalassemias. Transfusion. 2014 Apr;54(4):957-9. PubMed PMID: 24724786
• Ambruso DR, Sanchez R, Sloan SR, Josephson CD, the Pediatric TMAA Group. How do we teach pediatric topics in transfusion medicine: curriculum development, learners, and instructional strategies. Transfusion. 2013 Feb;53(2):250-256. PubMed PMID: 22519665
• Ambruso DR, Ellison MA, Thurman GW, Leto TL. Peroxiredoxin 6 translocates to the plasma membrane during neutrophil activation and is required for optimal NADPH oxidase activity. Biochim Biophys Acta. 2012 Feb;1823(2):306-15. PubMed PMID: 22178385
• Knipstein JA, Ambruso DR. Sweet syndrome in an infant with chronic granulomatous disease. J Pediatr Hematol Oncol. 2012 Jul;34(5):372-4. PubMed PMID: 22246153
• Ellison MA, Thurman GW, Ambruso DR. Phox activity of differentiated PLB-985 cells is enhanced, in an agonist specific manner, by the PLA2 activity of Prdx6-PLA2. Eur J Immunol. 2012 Jun;42(6):1609-17. PubMed PMID: 22678913
• Reesink HW, Lee J, Keller A, Dennington P, Pink J, Holdsworth R, Schennach H, Goldman M, Petraszko T, Sun J, Meng Y, Qian K, Rehacek V, Turek P, Krusius T, Juvonen E, Tiberghien P, Legrand D, Semana G, Muller JY, Bux J, Reil A, Lin CK, Daly H, McSweeney E, Porretti L, Greppi N, Rebulla P, Okazaki H, Sánchez-Guerrero SA, Baptista-González HA, Martínez-Murillo C, Guerra-Márquez A, Rodriguez-Moyado H, Middelburg RA, Wiersum-Osselton JC, Brand A, van Tilburg C, Dinesh D, Dagger J, Dunn P, Brojer E, Letowska M, Maslanka K, Lachert E, Uhrynowska M, Zhiburt E, Palfi M, Berlin G, Frey BM, Puig Rovira L, Muñiz-Diaz E, Castro E, Chapman C, Green A, Massey E, Win N, Williamson L, Silliman CC, Chaffin DJ, Ambruso DR, Blumberg N, Tomasulo P, Land KJ, Norris PJ, Illoh OC, Davey RJ, Benjamin RJ, Eder AF, McLaughlin L, Kleinman S, Panzer S. Measures to prevent transfusion-related acute lung injury (TRALI). Vox Sang. 2012 Oct;103(3):231-59. PubMed PMID: 22519920
• Ellison MA, Ambruso DR, Silliman CC. Therapeutic options for transfusion related acute lung injury; the potential of the G2A receptor. Curr Pharm Des. 2012;18(22):3255-9. PubMed PMID: 22621271
• Silliman CC, Kelher M, Ambruso DR. Bioactive lipids from stored cellular blood components: in vitro method is crucial for proper interpretation. Transfusion. 2012 May;52(5):1155-7; author reply 1157-8. PubMed PMID: 22571364

Professional Memberships

• American Pediatric Society (APS), Member
• Denver and Colorado Medical Societies , Member
• American Society of Hematology, Member
• AABB, formerly American Association of Blood Banks , Member
• Society For Pediatric Research (SPR), Member
• Western Society for Pediatric Research (WSPR), Member
• Society for Pediatric Hematology Oncology, Member