Kyros Ipaktchi, MD
Associate Professor, Orthopedics

Professional Titles

• Chief of Hand, Upper Extremity & Microvascular Surgery - Denver Health

Recognition & Awards

• Excellence in Medical Student Teaching Award, Department of Orthopedic Surgery, CU SOM (2023)
• Peer nominated “Top Doc – Hand Surgery", 5280 Denver Magazine (2022)
• Outstanding Clinician Award, Denver Health Medical Staff (2021)
• Denver Health Operative Staff Award, Denver Health Perioperative Team (2021)
• Peer nominated “Top Doc – Hand Surgery", 5280 Denver Magazine (2020)
• Peer nominated “Top Doc – Hand Surgery", 5280 Denver Magazine (2019)
• Peer nominated “Top Doc – Hand Surgery", 5280 Denver Magazine (2018)

Research Interests

Teaching

Publications

• Retrouvey H, Franks A, Dunn T, Novoa K, Ipaktchi K, Lauder A. Management of Self-Inflicted Nonaccidental Amputations of the Upper Extremity: Systematic Review. J Hand Surg Am. 2023 Oct;48(10):993-1002. PubMed PMID: 37589622
• Woods D, Newhoff D, Tucker N, Lauder A, Ipaktchi K. The safety and accuracy of various carpal tunnel injection techniques. Eur J Orthop Surg Traumatol. 2023 Oct;33(7):2995-2999. PubMed PMID: 36934360
• Ipaktchi K, Lauder A. Special edition: current practice and international perspectives in replantation and microvascular reconstruction in upper extremity traumatic amputation. Eur J Orthop Surg Traumatol. 2023 Oct 13. [Epub ahead of print] PubMed PMID: 37831147
• Retrouvey H, Ipaktchi K, Lauder A. Correction to: Evidence-based postoperative replantation protocols. Eur J Orthop Surg Traumatol. 2023 Oct 11. [Epub ahead of print] PubMed PMID: 37821632
• Retrouvey H, Lauder A, Ipaktchi K. Correction to: Is self-inflicted amputation to the upper extremity a contraindication to replantation?. Eur J Orthop Surg Traumatol. 2023 Oct 11. [Epub ahead of print] PubMed PMID: 37821631
• Retrouvey H, Ipaktchi K, Lauder A. Evidence-based postoperative replantation protocols. Eur J Orthop Surg Traumatol. 2023 Aug 28. [Epub ahead of print] PubMed PMID: 37639003
• Retrouvey H, Franks A, Dunn T, Novoa K, Ipaktchi K, Lauder A. Management of Self-Inflicted Nonaccidental Amputations of the Upper Extremity: Systematic Review. J Hand Surg Am. 2023 Oct;48(10):993-1002. PubMed PMID: 37589622
• Retrouvey H, Lauder A, Ipaktchi K. Is self-inflicted amputation to the upper extremity a contraindication to replantation?. Eur J Orthop Surg Traumatol. 2023 Aug 15. [Epub ahead of print] PubMed PMID: 37581643
• Woods D, Newhoff D, Tucker N, Lauder A, Ipaktchi K. The safety and accuracy of various carpal tunnel injection techniques. Eur J Orthop Surg Traumatol. 2023 Oct;33(7):2995-2999. PubMed PMID: 36934360
• Yu HH, Nadeau J, Powell J, Fox C, Lauder A, Ipaktchi K. The Iatrogenic Injury Potential of Self-adherent Elastic Bandages in Finger Injuries. Hand (N Y). 2023 Apr 13;:15589447231160208. [Epub ahead of print] PubMed PMID: 37056194
• Retrouvey H, Ipaktchi K, Lauder A. Evidence-based postoperative replantation protocols. Eur J Orthop Surg Traumatol. 2023 Aug 28. [Epub ahead of print] PubMed PMID: 37639003
• Retrouvey H, Lauder A, Ipaktchi K. Is self-inflicted amputation to the upper extremity a contraindication to replantation?. Eur J Orthop Surg Traumatol. 2023 Aug 15. [Epub ahead of print] PubMed PMID: 37581643
• Yu HH, Nadeau J, Powell J, Fox C, Lauder A, Ipaktchi K. The Iatrogenic Injury Potential of Self-adherent Elastic Bandages in Finger Injuries. Hand (N Y). 2023 Apr 13:15589447231160208. doi: 10.1177/15589447231160208. Epub ahead of print. PMID: 37056194.
• Douleh DG, Ipaktchi K, Lauder A. Hand Call Practices and Satisfaction: Survey Results From Hand Surgeons in the United States. J Hand Surg Am. 2022 Nov;47(11):1120.e1-1120.e9. PubMed PMID: 34756619
• Musculoskeletal Trauma, Conditions of the Extremity and Hand Injuries. Ipaktchi K, Morel S. In: 7th Edition Emergency Medicine Secrets. Editors: Bakes K, Buchanan J, Moreira M. Elsevier 2021
• Douleh DG, Ipaktchi K, Lauder A. Hand Call Practices and Satisfaction: Survey Results From Hand Surgeons in the United States. J Hand Surg Am. 2021 Oct 28. [Epub ahead of print] PubMed PMID: 34756619
• Rodriguez-Fontan F, Maertens AS, Parry JA, Stacey S, Lauder A, Ipaktchi K, Heare A, Hadeed M, Mauffrey C. From Dr. Miller E. Preston (1879-1928) to the Department of Orthopaedics at Denver Health Medical Center in Denver, CO. Int Orthop. 2021 Nov;45(11):2997-3001. PubMed PMID: 34328538
• Chen C, Scott F, Ipaktchi KR, Lauder A. Postoperative Digit and Hand Replantation Protocols: A Review of the Literature. J Am Acad Orthop Surg. 2021 Aug 1;29(15):e732-e742. PubMed PMID: 34185029
• Woods D, Cao J, Maddox G, Strage K, Lauder A, Ipaktchi K.: Pediatric Upper Extremity Escalator Entrapment JEMS, September 21, 2021
• Ipaktchi K, Morel S.. Musculoskeletal Trauma, Conditions of the Extremity and Hand Injuries. In: Markovchick, Pons, Bakes, and Buchanan: 7th Edition Emergency Medicine Secrets. Elsevier (2021)
• Ch 18: Carpus. Ipaktchi K, Dimachkieh O., Chaudhry S. in: Sports-related Fractures, Dislocations and Trauma: Advanced On- and Off-field Management. Editors: Khodaee, M., Waterbrook, A.L., Gammons, M Springer 2020
• Chaudhry S, Ipaktchi KR, Ignatiuk A. Updates on and Controversies Related to Management of Radial Nerve Injuries. J Am Acad Orthop Surg. 2019 Mar 15;27(6):e280-e284. PubMed PMID: 30856632
• Hak DJ, Banegas R, Ipaktchi K, Mauffrey C. Evolution of plate design and material composition. Injury. 2018 Jun;49 Suppl 1:S8-S11. PubMed PMID: 29929700
• Chaudhry S, Ipaktchi K, Ignatiuk A. Updates on and Controversies Related to Management of Radial Nerve Injuries. JAAOS Oct 13 2018. doi: 10.5435/JAAOS-D-17-00325
• Sundet A, Ipaktchi K, Kunrath C, Banegas RN. Management of the Pediatric Patient Following Upper Extremity Replantation or Revascularization: A Suggested Protocol. J Hand Surg Asian Pac Vol. 2017 Dec;22(4):479-483. PubMed PMID: 29117833
• Bosse MJ, Murray CK, Carlini AR, Firoozabadi R, Manson T, Scharfstein DO, Wenke JC, Zadnik M, Castillo RC. Assessment of Severe Extremity Wound Bioburden at the Time of Definitive Wound Closure or Coverage: Correlation With Subsequent Postclosure Deep Wound Infection (Bioburden Study). J Orthop Trauma. 2017 Apr;31 Suppl 1:S3-S9. PubMed PMID: 28323795
• Nguyen A, Ipaktchi K, Livermore M, Banegas R. Mycobacterium chelonae infection of the hand presenting as a collar-button abscess. Hand Surg. 2015;20(1):149-51. PubMed PMID: 25609291
• Chen W, Cheng J, Sun R, Zhang Z, Zhu Y, Ipaktchi K, Zhang Y. Prevalence and variation of sesamoid bones in the hand: a multi-center radiographic study. Int J Clin Exp Med. 2015;8(7):11721-6. PubMed PMID: 26380010
• Bowles RJ, Mitchell JJ, Price C, Ipaktchi K. Severe mycosis as a rare infection after a corn auger injury of the hand: a case report. Patient Saf Surg. 2015;9:22. PubMed PMID: 28428824
• Ipaktchi K, Seidl A, Banegas R, Hak D, Mauffrey C. Pirogoff amputation for a bilateral traumatic lower-extremity amputee: indication and technique. Orthopedics. 2014 Jun;37(6):397-401. PubMed PMID: 24972429
• Toker S, Oak N, Williams A, Ipaktchi K, Ozer K. Adherence to therapy after flexor tendon surgery at a level 1 trauma center. Hand (N Y). 2014 Jun;9(2):175-8. PubMed PMID: 24839418
• Bohn K, Ipaktchi K, Livermore M, Cao J, Banegas R. Current treatment concepts for "terrible triad" injuries of the elbow. Orthopedics. 2014 Dec;37(12):831-7. PubMed PMID: 25437075
• Wagner J, Ipaktchi K, Livermore M, Banegas R. Current indications for and the technique of wrist arthroscopy. Orthopedics. 2014 Apr;37(4):251-6. PubMed PMID: 24754550
• Karimkhani C, Amir M, Dellavalle RP, Ipaktchi K. Current concepts for oil decontamination of crush injuries: a review. Patient Saf Surg. 2014;8:22. PubMed PMID: 24855490
• Ipaktchi K, Livermore M, Lyons C, Banegas R. Current concepts in the treatment of distal radial fractures. Orthopedics. 2013 Oct 1;36(10):778-84. PubMed PMID: 24093691
• Ozer K, Ipaktchi K. Wind swept elbow: injury pattern and reconstruction. J Orthop Trauma. 2013 Jan;27(1):e9-12. PubMed PMID: 22549029
• Ipaktchi K, Kolnik A, Messina M, Banegas R, Livermore M, Price C. Current surgical instrument labeling techniques may increase the risk of unintentionally retained foreign objects: a hypothesis. Patient Saf Surg. 2013 Sep 30;7(1):31. PubMed PMID: 24079615
• Ipaktchi K, Demars A, Park J, Ciarallo C, Livermore M, Banegas R. Retained palmar foreign body presenting as a late hand infection: proposed diagnostic algorithm to detect radiolucent objects. Patient Saf Surg. 2013 Jul 11;7(1):25. PubMed PMID: 23844904
• Ozer K, Kiliç A, Sabel A, Ipaktchi K. The role of bone allografts in the treatment of angular malunions of the distal radius. J Hand Surg Am. 2011 Nov;36(11):1804-9. PubMed PMID: 22036280
• Niederbichler AD, Hoesel LM, Ipaktchi K, Olivarez L, Erdmann M, Vogt PM, Su GL, Arbabi S, Westfall MV, Wang SC, Hemmila MR. Burn-induced heart failure: lipopolysaccharide binding protein improves burn and endotoxin-induced cardiac contractility deficits. J Surg Res. 2011 Jan;165(1):128-35. PubMed PMID: 20085844
• Flierl MA, Rittirsch D, Weckbach S, Huber-Lang M, Ipaktchi K, Ward PA, Stahel PF. Disturbances of the hypothalamic-pituitary-adrenal axis and plasma electrolytes during experimental sepsis. Ann Intensive Care. 2011 Dec 30;1:53. PubMed PMID: 22208725
• Niederbichler AD, Papst S, Claassen L, Jokuszies A, Ipaktchi K, Reimers K, Hirsch T, Steinstraesser L, Kraft T, Vogt PM. Burn-induced organ dysfunction: vagus nerve stimulation improves cardiac function. Eplasty. 2010 Jun 21;10:e45. PubMed PMID: 20596235
• Gilman K, Ipaktchi K, Moore EE, Barnett C, Gurunluoglu R. Reconstruction of an emergency thoracotomy wound with free rectus abdominis flap: Anatomic and radiologic basis for the surgical technique. World J Emerg Surg. 2010 May 7;5:12. PubMed PMID: 20459668
• Niederbichler AD, Papst S, Claassen L, Jokuszies A, Steinstraesser L, Hirsch T, Altintas MA, Ipaktchi KR, Reimers K, Kraft T, Vogt PM. Burn-induced organ dysfunction: vagus nerve stimulation attenuates organ and serum cytokine levels. Burns. 2009 Sep;35(6):783-9. PubMed PMID: 19482432
• Hoesel LM, Mattar AF, Arbabi S, Niederbichler AD, Ipaktchi K, Su GL, Westfall MV, Wang SC, Hemmila MR. Local wound p38 MAPK inhibition attenuates burn-induced cardiac dysfunction. Surgery. 2009 Oct;146(4):775-85; discussion 785-6. PubMed PMID: 19789038
• Niederbichler AD, Ipaktchi K, Jokuszies A, Hirsch T, Altintas MA, Handschin AE, Busch KH, Gellert M, Steinau HU, Vogt PM, Steinsträsser L. [Surgical intensive care medicine. Current therapy concepts for septic diseases]. Chirurg. 2009 Oct;80(10):934-46. PubMed PMID: 19756430
• Ipaktchi K, Vogt PM. [Immunology and sepsis syndrome in burn trauma]. Unfallchirurg. 2009 May;112(5):472-8. PubMed PMID: 19440644
• Altintas AA, Altintas MA, Ipaktchi K, Guggenheim M, Theodorou P, Amini P, Spilker G. Assessment of microcirculatory influence on cellular morphology in human burn wound healing using reflectance-mode-confocal microscopy. Wound Repair Regen. 2009 Jul-Aug;17(4):498-504. PubMed PMID: 19614915
• Knobloch K, Ipaktchi K, Vogt PM. Shoulder proprioception after latissimus dorsi breast reconstruction. Plast Reconstr Surg. 2009 Jul;124(1):336-337. PubMed PMID: 19568123
• Benicke M, Perbix W, Lefering R, Knam F, Ipaktchi KR, Tannapfel A, Neugebauer EA, Spilker G. New multifactorial burn resuscitation formula offers superior predictive reliability in comparison to established algorithms. Burns. 2009 Feb;35(1):30-5. PubMed PMID: 18945549
• Schulze-Tanzil G, Müller RD, Kohl B, Schneider N, Ertel W, Ipaktchi K, Hünigen H, Gemeinhardt O, Stark R, John T. Differing in vitro biology of equine, ovine, porcine and human articular chondrocytes derived from the knee joint: an immunomorphological study. Histochem Cell Biol. 2009 Feb;131(2):219-29. PubMed PMID: 18839203
• Flierl MA, Stahel PF, Touban BM, Beauchamp KM, Morgan SJ, Smith WR, Ipaktchi KR. Bench-to-bedside review: Burn-induced cerebral inflammation--a neglected entity?. Crit Care. 2009;13(3):215. PubMed PMID: 19638180
• Knobloch K, Redeker B, Vogt PM, Ipaktchi K. The role of the reconstructive microsurgeon in preoperative perforator imaging. Microsurgery. 2009;29(3):247-8; author reply 249-50. PubMed PMID: 19205064
• Flierl MA, Stahel PF, Rittirsch D, Huber-Lang M, Niederbichler AD, Hoesel LM, Touban BM, Morgan SJ, Smith WR, Ward PA, Ipaktchi K. Inhibition of complement C5a prevents breakdown of the blood-brain barrier and pituitary dysfunction in experimental sepsis. Crit Care. 2009;13(1):R12. PubMed PMID: 19196477
• Rittirsch D, Flierl MA, Day DE, Nadeau BA, McGuire SR, Hoesel LM, Ipaktchi K, Zetoune FS, Sarma JV, Leng L, Huber-Lang MS, Neff TA, Bucala R, Ward PA. Acute lung injury induced by lipopolysaccharide is independent of complement activation. J Immunol. 2008 Jun 1;180(11):7664-72. PubMed PMID: 18490769
• Ipaktchi K, Ipaktchi R, Niederbichler AD, Vogt PM, Knobloch K. Unrecognized hand ischemia after intraarterial drug injection: successful management of a "near miss" event. Patient Saf Surg. 2008 Dec 9;2(1):32. PubMed PMID: 19068131
• Bravman JT, Ipaktchi K, Biffl WL, Stahel PF. Vascular injuries after minor blunt upper extremity trauma: pitfalls in the recognition and diagnosis of potential "near miss" injuries. Scand J Trauma Resusc Emerg Med. 2008 Nov 25;16:16. PubMed PMID: 19032757
• Ipaktchi K, Mattar A, Niederbichler AD, Kim J, Hoesel LM, Hemmila MR, Su GL, Remick DG, Wang SC, Arbabi S. Attenuating burn wound inflammation improves pulmonary function and survival in a burn-pneumonia model. Crit Care Med. 2007 Sep;35(9):2139-44. PubMed PMID: 17855827
• Chong M, Sochor M, Ipaktchi K, Brede C, Poster C, Wang S. The interaction of 'occupant factors' on the lower extremity fractures in frontal collision of motor vehicle crashes based on a level I trauma center. J Trauma. 2007 Mar;62(3):720-9. PubMed PMID: 17414354
• Hoesel LM, Niederbichler AD, Schaefer J, Ipaktchi KR, Gao H, Rittirsch D, Pianko MJ, Vogt PM, Sarma JV, Su GL, Arbabi S, Westfall MV, Wang SC, Hemmila MR, Ward PA. C5a-blockade improves burn-induced cardiac dysfunction. J Immunol. 2007 Jun 15;178(12):7902-10. PubMed PMID: 17548628
• Ipaktchi K, Mattar A, Niederbichler AD, Hoesel LM, Vollmannshauser S, Hemmila MR, Minter RM, Su GL, Wang SC, Arbabi S. Topical p38 MAPK inhibition reduces bacterial growth in an in vivo burn wound model. Surgery. 2007 Jul;142(1):86-93. PubMed PMID: 17630004
• Arbabi S, Campion EM, Hemmila MR, Barker M, Dimo M, Ahrns KS, Niederbichler AD, Ipaktchi K, Wahl WL. Beta-blocker use is associated with improved outcomes in adult trauma patients. J Trauma. 2007 Jan;62(1):56-61; discussion 61-2. PubMed PMID: 17215733
• Ipaktchi K, Arbabi S. Advances in burn critical care. Crit Care Med. 2006 Sep;34(9 Suppl):S239-44. PubMed PMID: 16917429
• Niederbichler AD, Hoesel LM, Westfall MV, Gao H, Ipaktchi KR, Sun L, Zetoune FS, Su GL, Arbabi S, Sarma JV, Wang SC, Hemmila MR, Ward PA. An essential role for complement C5a in the pathogenesis of septic cardiac dysfunction. J Exp Med. 2006 Jan 23;203(1):53-61. PubMed PMID: 16380509
• Niederbichler AD, Westfall MV, Su GL, Donnerberg J, Usman A, Vogt PM, Ipaktchi KR, Arbabi S, Wang SC, Hemmila MR. Cardiomyocyte function after burn injury and lipopolysaccharide exposure: single-cell contraction analysis and cytokine secretion profile. Shock. 2006 Feb;25(2):176-83. PubMed PMID: 16525357
• Ipaktchi K, Mattar A, Niederbichler AD, Hoesel LM, Vollmannshauser S, Hemmila MR, Su GL, Remick DG, Wang SC, Arbabi S. Attenuating burn wound inflammatory signaling reduces systemic inflammation and acute lung injury. J Immunol. 2006 Dec 1;177(11):8065-71. PubMed PMID: 17114480
• Ipaktchi K, Mattar A, Niederbichler AD, Hoesel LM, Hemmila MR, Su GL, Remick DG, Wang SC, Arbabi S. Topical p38MAPK inhibition reduces dermal inflammation and epithelial apoptosis in burn wounds. Shock. 2006 Aug;26(2):201-9. PubMed PMID: 16878030
• Minter RM, Fan MH, Sun J, Niederbichler A, Ipaktchi K, Arbabi S, Hemmila MR, Remick DG, Wang SC, Su GL. Altered Kupffer cell function in biliary obstruction. Surgery. 2005 Aug;138(2):236-45. PubMed PMID: 16153432
• Wang SC, Brede C, Lange D, Poster CS, Lange AW, Kohoyda-Inglis C, Sochor MR, Ipaktchi K, Rowe SA, Patel S, Garton HJ. Gender differences in hip anatomy: possible implications for injury tolerance in frontal collisions. Annu Proc Assoc Adv Automot Med. 2004;48:287-301. PubMed PMID: 15319131

Professional Memberships

• Orthopedic Trauma Association (OTA), Member
• American College of Surgeons, Fellow
• Western Orthopedic Association, Member
• American Academy Orthopedic Surgery, Fellow