Rachelle Nuss, MD
Professor, Pediatrics-Heme/Onc and Bone Marrow Transplantation

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Medical School:
  • MD, Wayne State University School of Medicine (1981)
Undergraduate School:
  • BS, Wayne State University (MI) (1977)
Residency:
  • Children's Hospital/Boston Medical Center Program, Pediatrics (1984)
Fellowships:
  • St. Jude Children's Research Hospital, Pediatric Hematology / Oncology (1987)
Languages: English
Department: Pediatrics-Heme/Onc and Bone Marrow Transplantation

Research Interests

I conduct research studies involving patients with hemoglobinopathies.

Publications

  • Buehler PW, Swindle D, Pak DI, Ferguson SK, Majka SM, Karoor V, Moldovan R, Sintas C, Black J, Gentinetta T, Buzzi RM, Vallelian F, Wassmer A, Edler M, Bain J, Schu D, Hassell K, Nuss R, Schaer DJ, Irwin DC. Hemopexin dosing improves cardiopulmonary dysfunction in murine sickle cell disease. Free Radic Biol Med. 2021 Nov 1;175:95-107. PubMed PMID: 34478834
  • Underdown MJ, Nuss R. Thrombocytopenia in a teen with sickle cell disease following COVID-19 vaccination. Pediatr Blood Cancer. 2021 Dec;68(12):e29271. PubMed PMID: 34331506
  • Casella JF, Barton BA, Kanter J, Black LV, Majumdar S, Inati A, Wali Y, Drachtman RA, Abboud MR, Kilinc Y, Fuh BR, Al-Khabori MK, Takemoto CM, Salman E, Sarnaik SA, Shah N, Morris CR, Keates-Baleeiro J, Raj A, Alvarez OA, Hsu LL, Thompson AA, Sisler IY, Pace BS, Noronha SA, Lasky JL 3rd, de Julian EC, Godder K, Thornburg CD, Kamberos NL, Nuss R, Marsh AM, Owen WC, Schaefer A, Tebbi CK, Chantrain CF, Cohen DE, Karakas Z, Piccone CM, George A, Fixler JM, Singleton TC, Moulton T, Quinn CT, de Castro Lobo CL, Almomen AM, Goyal-Khemka M, Maes P, Emanuele M, Gorney RT, Padgett CS, Parsley E, Kronsberg SS, Kato GJ, Gladwin MT. Effect of Poloxamer 188 vs Placebo on Painful Vaso-Occlusive Episodes in Children and Adults With Sickle Cell Disease: A Randomized Clinical Trial. JAMA. 2021 Apr 20;325(15):1513-1523. PubMed PMID: 33877274
  • Loi M, Branchford B, Kim J, Self C, Nuss R. COVID-19 anticoagulation recommendations in children. Pediatr Blood Cancer. 2020 Jun 18;:e28485. [Epub ahead of print] PubMed PMID: 32558124
  • A quality initiative to decrease time to antibiotics in children with sickle cell disease and fever. McKinney C, Caruso-Brown A, Montgomery K, et al. Nuss R. Pediatric Quality and Safety: January/February 2020-volume5-issue 1-pe245 doi: 10.1097/pq9.0000000245
  • Loi M, Branchford B, Kim J, Self C, Nuss R. COVID-19 anticoagulation recommendations in children. Pediatr Blood Cancer. 2020 Sep;67(9):e28485. PubMed PMID: 32558124
  • Redinus K, Baek JH, Yalamanoglu A, Shin HKH, Moldova R, Harral JW, Swindle D, Pak D, Ferguson SK, Nuss R, Hassell K, Nozik-Grayck E, Palmer AF, Fini MA, Karoor V, Stenmark KR, Buehler PW, Irwin DC. An Hb-mediated circulating macrophage contributing to pulmonary vascular remodeling in sickle cell disease. JCI Insight. 2019 Aug 8;4(15). PubMed PMID: 31391342
  • Ferguson SK, Redinius K, Yalamanoglu A, Harral JW, Hyen Baek J, Pak D, Loomis Z, Hassell D, Eigenberger P, Nozik-Grayck E, Nuss R, Hassell K, Stenmark KR, Buehler PW, Irwin DC. Effects of living at moderate altitude on pulmonary vascular function and exercise capacity in mice with sickle cell anaemia. J Physiol. 2019 Feb;597(4):1073-1085. PubMed PMID: 29931797
  • Lisk C, Kominsky D, Ehrentraut S, Bonaventura J, Nuss R, Hassell K, Nozik-Grayck E, Irwin DC. Hemoglobin-induced endothelial cell permeability is controlled, in part, via a myeloid differentiation primary response gene-88-dependent signaling mechanism. Am J Respir Cell Mol Biol. 2013 Oct;49(4):619-26. PubMed PMID: 23713977
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Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation
  • Children's Hospital Colorado
Center Affiliations

Specialty Information

Specialties
  • Pediatrics, Board Certification
  • Pediatric Hematology / Oncology, Board Certification
Conditions & Treatments
  • Cancers
  • Blood / Lymphatic System - Blood Disorders
  • Blood / Lymphatic System - Bleeding Disorders
  • Blood / Lymphatic System
Clinical Interests
I provide direct care for patients with hemoglobinopathies with a focus on sickle cell disease.

Care Philosophy
My goal is to understand the families wishes and work collaboratively to satisfy them.

Personal Interests
Hobbies: hiking with dogs, running with dogs, fostering dogs and cats

General Information

Medical Schools:
  • MD, Wayne State University School of Medicine (1981)
Undergraduate Schools:
  • BS, Wayne State University (MI) (1977)
Residency Programs:
  • Children's Hospital/Boston Medical Center Program, Pediatrics (1984)
Fellowships:
  • St. Jude Children's Research Hospital, Pediatric Hematology / Oncology (1987)
Languages: English
Department: Pediatrics-Heme/Onc and Bone Marrow Transplantation
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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