Shikha Sundaram, MD
Associate Professor, Pediatrics-Gastroenterology, Hepatology and Nutrition

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Medical School:
  • MD, University of Kentucky College of Medicine (1998)
Residency:
  • McGaw Medical Center of Northwestern University/Children's Memorial Hospital Program, Pediatrics (2001)
Fellowships:
  • McGaw Medical Center of Northwestern University Program, Advanced Hepatology (2005)
  • McGaw Medical Center of Northwestern University Program, Pediatric Gastroenterology, Hepatology & Nutrition (2004)
Languages: English
Department: Pediatrics-Gastroenterology, Hepatology and Nutrition

Publications

  • Shneider BL, Goodrich NP, Ye W, Sawyers C, Molleston JP, Merion RM, Leung DH, Karpen SJ, Kamath BM, Cavallo L, Wang K, Teckman JH, Squires JE, Sundaram SS, Rosenthal P, Romero R, Murray KF, Loomes KM, Jensen MK, Bezerra JA, Bass LM, Sokol RJ, Magee JC. Nonfasted Liver Stiffness Correlates with Liver Disease Parameters and Portal Hypertension in Pediatric Cholestatic Liver Disease. Hepatol Commun. 2020 Nov;4(11):1694-1707. PubMed PMID: 33163838
  • Kemme S, Sundaram SS, Curtis DJ, Lobritto S, Mohammad S, Feldman AG. A community divided: Post-transplant live vaccine practices among Society of Pediatric Liver Transplantation (SPLIT) centers. Pediatr Transplant. 2020 Nov;24(7):e13804. PubMed PMID: 32845536
  • Leung DH, Squires JE, Jhaveri R, Kerkar N, Lin CH, Mohan P, Murray KF, Gonzalez-Peralta RP, Roberts EA, Sundaram SS. Hepatitis C in 2020: A North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Position Paper. J Pediatr Gastroenterol Nutr. 2020 Sep;71(3):407-417. PubMed PMID: 32826718
  • Feng S, Bucuvalas JC, Mazariegos GV, Magee JC, Sanchez-Fueyo A, Spain KM, Lesniak A, Kanaparthi S, Perito E, Venkat VL, Burrell BE, Alonso EM, Bridges ND, Doo E, Gupta NA, Himes RW, Ikle D, Jackson AM, Lobritto SJ, Jose Lozano J, Martinez M, Ng VL, Rand EB, Sherker AH, Sundaram SS, Turmelle YP, Wood-Trageser M, Demetris AJ. Efficacy and Safety of Immunosuppression Withdrawal in Pediatric Liver Transplant Recipients: Moving Towards Personalized Management. Hepatology. 2020 Aug 12. [Epub ahead of print] PubMed PMID: 32786149
  • Ibrahim SH, Jonas MM, Taylor SA, Gutierrez Sanchez LH, Wolf JL, Sundaram SS. Liver Diseases in the Perinatal Period: Interactions Between Mother and Infant. Hepatology. 2020 Apr;71(4):1474-1485. PubMed PMID: 31925801
  • Mack CM and Sundaram SS. Abnormalities of Carbohydrate Metabolism and the Liver” in R Wylie and JS Hyams (eds), Pediatric Gastrointestinal Disease 6th edition London; Elsevier Limited
  • Orr WC, Fass R, Sundaram SS, Scheimann AO. The effect of sleep on gastrointestinal functioning in common digestive diseases. Lancet Gastroenterol Hepatol. 2020 Jun;5(6):616-624. doi: 10.1016/S2468-1253(19)30412-1. Review. PubMed PMID: 32416862.
  • Successful Liver-Kidney Transplantation in a Highly Sensitized Pediatric Patient Margret Bock MD MS, Mary Chandran PharmD, Jens Goebel, MD, Eliza Blanchette MD MS, Michael Wachs MD, Megan Adams MD, Shikha Sundaram MD MSCI
  • The Impact of Non-Directed Anonymous Live Liver Donors on the Volume of Children on the Waitlist at a Single Pediatric Liver Transplant Center D Yoeli, MA Adams, ME Wachs, SS Sundaram, RA Choudhury, KD Conzen, JR Burton, EA Pomfret, WE Jackson
  • ASSOCIATION OF SERUM BIOMARKERS WITH LIVER STIFFNESS ASSESSED BY TRANSIENT ELASTOGRAPHY IN 330 CHILDREN WITH CHOLESTATIC LIVER DISEASE Dr. Daniel H. Leung , Sridevi Gavaraj , Nathan P. Goodrich , Xinpu Chen , Deepthi B Rajapakshe , Wen Ye , Victor Andreev , Charles Minard , Ms. Danielle Gu??ey , Dr. Jean Pappas Molleston , Dr. Lee M. Bass , Dr. Saul J Karpen, MD, PhD, FAASLD , Dr. Binita M. Kamath , Dr.Kasper S Wang , Dr. Shikha S Sundaram , Dr. Philip Rosenthal , Prof. Patrick James McKiernan , Dr. Kathleen M. Loomes , Dr. M. Kyle Jensen , Dr. Simon P Horslen , Dr. Jorge A. Bezerra, MD, FAASLD , Dr. John C Magee, MD , Dr. Robert Merion , Dr. Ronald J Sokol and Dr. Benjamin L Shneider
  • BILIARY STRICTURE PTC OR ERCP MANAGEMENT STRATEGIES IN KIDS POST-LIVER TRANSPLANT: MULTICENTER ANALYSIS FROM THE SOCIETY OF PEDIATRIC LIVER TRANSPLANTATION REGISTRY Dr. Pamela L. Valentino , Tianhao Wang , Veronika Shabanova , Dr. Vicky Lee Ng , Dr. John C. Bucuvalas, MD, FAASLD , Dr. Amy Feldman , Dr. Regino P Gonzalez-Peralta , Dr. Nitika A Gupta , Dr. Tamir A Miloh , Dr. Saeed Mohammad , Dr. Erika Pace , Dr. Shikha S Sundaram , Dr.Nada A. Yazigi , Dr. Kyle Soltys and Society of Pediatric Liver Transplantation (SPLIT)
  • PHENOTYPIC DIVERGENCE OF JAGGED1 AND NOTCH2-ASSOCIATED ALAGILLE SYNDROME: RESULTS FROM THE INTERNATIONAL MULTICENTER GALA STUDY GROUP 1. Vandriel SM, Li L, She H, Wang JS, Gilbert MA, Spinner NB, Loomes KM, Piccoli DA, D’Antiga L, Nicastro E, Calvo PL, Hardikar W, Shankar S, Fawaz RL, Nastasio S, Bulut P, Jankowska I, Czubkowski P, Gliwicz-Miedzinska D, Sokal E, Demaret T, Siew SM, Stormon M, Lacaille F, Debray D, Kim KM, Baek WY, Feinstein JA, Ebel NH, Karpen SJ, Romero R, Karthikeyan P, Davison S, Arnell H, Fischler B, Squires JE, Verkade HJ, Jensen MK, Kavan M, Roberts AJ, Evans HM, Lertudomphonwanit C, Lee WS, Sundaram SS, Chaidez A, Fischer RT, Mozer-Glassberg Y, Larson-Nath C, Lin H, Bujanda L, Kelly D, Karnsakul W, Quintero-Bernabeu J, Indolfi G, Mujawar Q, Valentino PL, Nebbia G, Quiros-Tejeira RE, Kerkar N, Schwarz K, Wolters VM, Alam S, Jimenez-Rivera C, Santos-Silva E, Brecelj J, Sanchez MC, Cavalieri ML, Desai DM, Önal Z, Legarda-Tamara M, Molera C, Arikan C, Wiecek S, Gonzales EM, Thompson RJ, Hansen BE, Kamath BM, and The GALA Study Group.
  • PREDICTORS OF SURVIVAL FOLLOWING LIVER TRANSPLANTATION FOR PEDIATRIC LIVER TUMORS: EXPERIENCE FROM THE SOCIETY OF PEDIATRIC LIVER TRANSPLANTATION (SPLIT) Julia M Boster1, Riccardo Superina2, George V Mazariegos3, Gregory M Tiao4, Jonathan P Roach1, Mark A Lovell1, Brian S Greffe1, George Yanni5, Caroline Lemoine2, Daniel H Leung6, Scott Elisofon7, Susan V McDiarmid8, Nitika A Gupta9, Steven J Lobritto10, Janis M Stoll11, Bernadette E Vitola12, James F Daniel13, Blayne A Sayed14, Dev M Desai15, Abigail E Martin16, Arpit Amin3, Ravinder Anand17, Sarah G Anderson17, Shikha S Sundaram1
  • The Co-Occurrence of Hereditary Galactosemia and Biliary Atresia in a Jaundiced Neonate Boster, Baker, Karrer Bodmer, Kripps and Sundaram
  • CLINICAL PRESENTATION AND MANAGEMENT OF A NEONATE WITH A CONGENITAL INTRAHEPATIC PORTOSYSTEMIC SHUNT A. Goldberg, R. Shay, S. Sundaram, C. Wright, A. Annam, R. Shay, C. Wright
  • HIGHER MORTALITY IN PEDIATRIC LIVER TRANSPLANT CANDIDATES WITH SARCOPENIA J. M. Boster, L. P. Browne, Z. Pan, W. Zhou, P. F. Ehrlich, S. Sundaram
  • WAITING LIST AT A SINGLE LIVER TRANSPLANT CENTER D. Yoeli, W. Jackson, M. Adams, M. Wachs, S. Sundaram, J. Cisek, R. Choudhury, T. Nydm, J. Pomposelli, K. Conzen, M. Kriss3, J. Burton, E. Pomfret
  • Elisofon SA, Magee JC, Ng VL, Horslen SP, Fioravanti V, Economides J, Erinjeri J, Anand R, Mazariegos GV. Society of pediatric liver transplantation: Current registry status 2011-2018. Pediatr Transplant. 2019 Nov 3;:e13605. [Epub ahead of print] PubMed PMID: 31680409
  • Ohnemus D, Neighbors K, Rychlik K, Venick RS, Bucuvalas JC, Sundaram SS, Ng VL, Andrews WS, Turmelle Y, Mazariegos GV, Sorensen LG, Alonso EM. Health-Related Quality of Life and Cognitive Functioning in Pediatric Liver Transplant Recipients. Liver Transpl. 2019 Sep 11. [Epub ahead of print] PubMed PMID: 31509650
  • Shapiro WL, Yu EL, Arin JC, Murray KF, Ali S, Desai NK, Xanthakos SA, Lin HC, Alkhouri N, Abdou R, Abrams SH, Butler MW, Faasse SA, Gillis LA, Hadley TA, Jain AK, Kavan M, Kordy K, Lee P, Panganiban J, Pohl JF, Potter C, Rudolph B, Sundaram SS, Joshi S, Proudfoot JA, Goyal NP, Harlow KE, Newton KP, Schwimmer JB. Clinical Practice Approach to Nonalcoholic Fatty Liver Disease by Pediatric Gastroenterologists in the United States. J Pediatr Gastroenterol Nutr. 2019 Feb;68(2):182-189. PubMed PMID: 30640271
  • Feldman AG, Sundaram SS, Beaty BL, Torres R, Curtis DJ, Kempe A. Immunization Status at the Time of Liver Transplant in Children and Adolescents. JAMA. 2019 Nov 12;322(18):1822-1824. PubMed PMID: 31714979
  • Black DD, Mack C, Kerkar N, Miloh T, Sundaram SS, Anand R, Gupta A, Alonso E, Arnon R, Bulut P, Karpen S, Lin CH, Rosenthal P, Ryan M, Squires RH, Valentino P, Elsea SH, Shneider BL. A Prospective Trial of Withdrawal and Reinstitution of Ursodeoxycholic Acid in Pediatric Primary Sclerosing Cholangitis. Hepatol Commun. 2019 Nov;3(11):1482-1495. PubMed PMID: 31701072
  • Mouzaki M, Bronsky J, Gupte G, Hojsak I, Jahnel J, Pai N, Quiros-Tejeira RE, Wieman R, Sundaram S. Nutrition Support of Children With Chronic Liver Diseases: A Joint Position Paper of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition. J Pediatr Gastroenterol Nutr. 2019 Oct;69(4):498-511. PubMed PMID: 31436707
  • Ng VL, Mazariegos GV, Kelly B, Horslen S, McDiarmid SV, Magee JC, Loomes KM, Fischer RT, Sundaram SS, Lai JC, Te HS, Bucuvalas JC. Barriers to ideal outcomes after pediatric liver transplantation. Pediatr Transplant. 2019 Sep;23(6):e13537. PubMed PMID: 31343109
  • Sundaram SS, Halbower AC, Klawitter J, Pan Z, Robbins K, Capocelli KE, Sokol RJ. Treating Obstructive Sleep Apnea and Chronic Intermittent Hypoxia Improves the Severity of Nonalcoholic Fatty Liver Disease in Children. J Pediatr. 2018 Jul;198:67-75.e1. PubMed PMID: 29752170
  • Lurz E, Quammie C, Englesbe M, Alonso EM, Lin HC, Hsu EK, Furuya KN, Gupta NA, Venkat VL, Daniel JF, Leonis MA, Miloh T, Telega GW, Yap J, Menendez J, Book LS, Himes RW, Sundaram SS, Parekh R, Sonnenday C, Bucuvalas J, Ng VL, Kamath BM. Frailty in Children with Liver Disease: A Prospective Multicenter Study. J Pediatr. 2018 Mar;194:109-115.e4. PubMed PMID: 29478492
  • Mehta P, Furuta GT, Brennan T, Henry ML, Maune NC, Sundaram SS, Menard-Katcher C, Atkins D, Takurukura F, Giffen S, Pan Z, Haas AM. Nutritional State and Feeding Behaviors of Children With Eosinophilic Esophagitis and Gastroesophageal Reflux Disease. J Pediatr Gastroenterol Nutr. 2018 Apr;66(4):603-608. PubMed PMID: 28906318
  • Feng S, Bucuvalas JC, Demetris AJ, Burrell BE, Spain KM, Kanaparthi S, Magee JC, Ikle D, Lesniak A, Lozano JJ, Alonso EM, Bray RA, Bridges NE, Doo E, Gebel HM, Gupta NA, Himes RW, Jackson AM, Lobritto SJ, Mazariegos GV, Ng VL, Rand EB, Sherker AH, Sundaram S, Turmelle YP, Sanchez-Fueyo A. Evidence of Chronic Allograft Injury in Liver Biopsy Samples From Long-Term Pediatric Recipients of Liver Transplants. Gastroenterology. 2018 Aug 23. [Epub ahead of print] PubMed PMID: 30144432
  • Feng S, Bucuvalas JC, Demetris AJ, Burrell BE, Spain KM, Kanaparthi S, Magee JC, Ikle D, Lesniak A, Lozano JJ, Alonso EM, Bray RA, Bridges NE, Doo E, Gebel HM, Gupta NA, Himes RW, Jackson AM, Lobritto SJ, Mazariegos GV, Ng VL, Rand EB, Sherker AH, Sundaram S, Turmelle YP, Sanchez-Fueyo A. Evidence of Chronic Allograft Injury in Liver Biopsies From Long-term Pediatric Recipients of Liver Transplants. Gastroenterology. 2018 Dec;155(6):1838-1851.e7. PubMed PMID: 30144432
  • Vos MB, Abrams SH, Barlow SE, Caprio S, Daniels SR, Kohli R, Mouzaki M, Sathya P, Schwimmer JB, Sundaram SS, Xanthakos SA. Response to the Letters Regarding the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition NAFLD Guidelines. J Pediatr Gastroenterol Nutr. 2017 Nov;65(5):e115-e116. PubMed PMID: 29059122
  • Mehta P, Furuta GT, Brennan T, Henry ML, Maune NC, Sundaram SS, Menard-Katcher C, Atkins D, Takurukura F, Giffen S, Pan Z, Haas AM. Nutritional State and Feeding Behaviors of Children With Eosinophilic Esophagitis and Gastroesophageal Reflux Disease. J Pediatr Gastroenterol Nutr. 2017 Sep 12. [Epub ahead of print] PubMed PMID: 28906318
  • Vos MB, Abrams SH, Barlow SE, Caprio S, Daniels SR, Kohli R, Mouzaki M, Sathya P, Schwimmer JB, Sundaram SS, Xanthakos SA. Response to Letters Regarding the NASPGHAN NAFLD Guidelines. J Pediatr Gastroenterol Nutr. 2017 Sep 1. [Epub ahead of print] PubMed PMID: 28872475
  • Sheiko MA, Sundaram SS, Capocelli KE, Pan Z, McCoy AM, Mack CL. Outcomes in Pediatric Autoimmune Hepatitis and Significance of Azathioprine Metabolites. J Pediatr Gastroenterol Nutr. 2017 Jul;65(1):80-85. PubMed PMID: 28272159
  • Vos MB, Abrams SH, Barlow SE, Caprio S, Daniels SR, Kohli R, Mouzaki M, Sathya P, Schwimmer JB, Sundaram SS, Xanthakos SA. NASPGHAN Clinical Practice Guideline for the Diagnosis and Treatment of Nonalcoholic Fatty Liver Disease in Children: Recommendations from the Expert Committee on NAFLD (ECON) and the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN). J Pediatr Gastroenterol Nutr. 2017 Feb;64(2):319-334. PubMed PMID: 28107283
  • Feldman AG, Sundaram SS, Beaty BL, Kempe A. Hospitalizations for Respiratory Syncytial Virus and Vaccine-Preventable Infections in the First 2 Years After Pediatric Liver Transplant. J Pediatr. 2017 Mar;182:232-238.e1. PubMed PMID: 28088400
  • Sundaram SS, Mack CL, Feldman AG, Sokol RJ. Biliary atresia: Indications and timing of liver transplantation and optimization of pretransplant care. Liver Transpl. 2017 Jan;23(1):96-109. PubMed PMID: 27650268
  • Mehta P, Sundaram SS, Furuta GT, Pan Z, Atkins D, Markowitz S. Propofol Use in Pediatric Patients With Food Allergy and Eosinophilic Esophagitis. J Pediatr Gastroenterol Nutr. 2017 Apr;64(4):546-549. PubMed PMID: 27276432
  • Vos MB, Abrams SH, Barlow SE, Caprio S, Daniels SR, Kohli R, Mouzaki M, Sathya P, Schwimmer JB, Sundaram SS, Xanthakos SA. NASPGHAN Clinical Practice Guideline for the Diagnosis and Treatment of Nonalcoholic Fatty Liver Disease in Children. J Pediatr Gastroenterol Nutr. 2016 Nov 30. [Epub ahead of print] PubMed PMID: 27906803
  • Sundaram SS, Halbower A, Pan Z, Robbins K, Capocelli KE, Klawitter J, Shearn CT, Sokol RJ. Nocturnal hypoxia-induced oxidative stress promotes progression of pediatric non-alcoholic fatty liver disease. J Hepatol. 2016 Sep;65(3):560-9. PubMed PMID: 27501738
  • Feldman AG, Kempe A, Beaty BL, Sundaram SS. Immunization practices among pediatric transplant hepatologists. Pediatr Transplant. 2016 Dec;20(8):1038-1044. PubMed PMID: 27449120
  • Kohli R, Sunduram S, Mouzaki M, Ali S, Sathya P, Abrams S, Xanthakos SA, Vos M, Schwimmer JB. Pediatric Nonalcoholic Fatty Liver Disease: A Report from the Expert Committee on Nonalcoholic Fatty Liver Disease (ECON). J Pediatr. 2016 May;172:9-13. PubMed PMID: 26749112
  • Sundaram SS, Halbower A, Pan Z, Robbins K, Capocelli KE, Klawitter J, Shearn CT, Sokol RJ. Nocturnal hypoxia-induced oxidative stress promotes progression of pediatric non-alcoholic fatty liver disease. J Hepatol. 2016 Sep;65(3):560-9. PubMed PMID: 27501738
  • Feldman AG, Kempe A, Beaty BL, Sundaram SS. Immunization practices among pediatric transplant hepatologists. Pediatr Transplant. 2016 Dec;20(8):1038-1044. PubMed PMID: 27449120
  • Kohli R, Sunduram S, Mouzaki M, Ali S, Sathya P, Abrams S, Xanthakos SA, Vos M, Schwimmer JB. Pediatric Nonalcoholic Fatty Liver Disease: A Report from the Expert Committee on Nonalcoholic Fatty Liver Disease (ECON). J Pediatr. 2016 May;172:9-13. PubMed PMID: 26749112
  • Sullivan JS, Le MT, Pan Z, Rivard C, Love-Osborne K, Robbins K, Johnson RJ, Sokol RJ, Sundaram SS. Oral fructose absorption in obese children with non-alcoholic fatty liver disease. Pediatr Obes. 2015 Jun;10(3):188-95. PubMed PMID: 24961681
  • Hurst AL, Clark N, Carpenter TC, Sundaram SS, Reiter PD. Supra-therapeutic tacrolimus concentrations associated with concomitant nicardipine in pediatric liver transplant recipients. Pediatr Transplant. 2015 Jun;19(4):E83-7. PubMed PMID: 25850753
  • Sullivan JS, Le MT, Pan Z, Rivard C, Love-Osborne K, Robbins K, Johnson RJ, Sokol RJ, Sundaram SS. Oral fructose absorption in obese children with non-alcoholic fatty liver disease. Pediatr Obes. 2014 Jun 24. [Epub ahead of print] PubMed PMID: 24961681
  • Sundaram SS, Sokol RJ, Capocelli KE, Pan Z, Sullivan JS, Robbins K, Halbower AC. Obstructive sleep apnea and hypoxemia are associated with advanced liver histology in pediatric nonalcoholic fatty liver disease. J Pediatr. 2014 Apr;164(4):699-706.e1. PubMed PMID: 24321532
  • Suchy FJ, Sundaram S, and Shneider BL: Familial hepatocellular cholestasis. In: Liver Disease in Children. 5th ed., Suchy FJ, Sokol RJ, and Balistreri WF: Cambridge University Press, Cambridge, (In Press).
  • 18. Sokol RJ, Narkewicz MR, JA Mark, CL Mack, AG Feldman, Sundaram SS: Liver & Pancreas. In: Hay WW, Levin MJ, Deterding RR, Abzug MJ, (eds), Current Pediatric Diagnosis ? Treatment, 25th edition McGraw-Hill Medical, NY NY, 2020.
  • Feldman AG, Adams M, Wachs M, Abzug MJ, Pratscher L, Jackson WE, Pomfret EA, Sundaram SS. Successful Non-directed Living Donor Liver Transplant for an Infant with Biliary Atresia During the COVID-19 Pandemic, Pediatric Transplantation, Accepted July 2020
  • Improvements in Disease Specific Health-related Quality of Life of Pediatric Liver Transplant Recipients During Immunosuppression Withdrawal Liver Transplantation, in press Mohammed S, Sundaram S, et al.
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Professional Memberships

  • American Association for the Study of Liver Diseases, Member
  • North American Society of Pediatric Gastroenterology, Hepatology and Nutrition, Member
  • American Gastroenterological Association, Member
  • American College of Gastroenterology, Member

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation
  • Children's Hospital Colorado
  • University of Colorado Hospital

Specialty Information

Specialties
  • Pediatric Gastroenterology, Board Certification (2006)
  • Pediatric Transplant Hepatology, Board Certification
  • Pediatrics, Board Certification
Conditions & Treatments
  • Digestive System - Gastroenterology (Stomach, Bowel, General GI Problems)
  • Surgery - Liver Transplant Surgery
  • Digestive System - Hepatology (Liver Disorders)
  • Digestive System
  • Surgery
Clinical Interests
My clinical interests include pediatric liver disease, pediatric liver transplant and pediatric non-alcoholic fatty liver disease.

General Information

Medical Schools:
  • MD, University of Kentucky College of Medicine (1998)
Residency Programs:
  • McGaw Medical Center of Northwestern University/Children's Memorial Hospital Program, Pediatrics (2001)
Fellowships:
  • McGaw Medical Center of Northwestern University Program, Advanced Hepatology (2005)
  • McGaw Medical Center of Northwestern University Program, Pediatric Gastroenterology, Hepatology & Nutrition (2004)
Languages: English
Department: Pediatrics-Gastroenterology, Hepatology and Nutrition
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