Dunbar Ivy, MD
Professor, Pediatrics-Cardiology

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Medical School:
  • MD, Tulane University School of Medicine (1988)
Undergraduate School:
  • BS, Davidson College (NC) (1984)
Internship:
  • University of Colorado (Children's Hospital Colorado) Program (1989)
Residency:
  • University of Colorado (Children's Hospital Colorado) Program, Pediatrics (1991)
Fellowships:
  • University of Colorado (Children's Hospital Colorado) Program, Pediatric Cardiology (1994)
Languages: English
Department: Pediatrics-Cardiology

Professional Titles

  • Professor, Pediatrics-Cardiology
  • Selby's Chair in Pediatric Cardiology

Recognition & Awards

  • 5280 Magazine Top Docs, 5280 Magazine, (2018)
  • 5280 Magazine Top Docs , 5280 Magazine , (2017)
  • 5280 Magazine Top Docs , 5280 Magazine , (2016)
  • 5280 Magazine Top Docs, 5280 Magazine, (2015)
  • 5280 Magazine Top Docs, 5280 Magazine , (2015)
  • 5280 Magazine Top Docs, 5280 Magazine, (2014)
  • 5280 Magazine Top Docs, 5280 Magazine, (2013)
  • Heart Who Cares Award, The Children's Hospital Heart Institute, (2012)
  • Selby‚Äôs Endowed Chair of Pediatric Cardiology, The Children's Hospital, (2003)
  • Children's Choice Award, The Children's Hospital, (2001)
    Pulmonary Hypertension Program
Research interests for Patients:
I am interested in new ways to diagnose and treat pulmonary hypertension in children.

Publications

  • Schäfer M, Frank BS, Ivy DD, Wilson N, Morgan GJ, Barker AJ, Browne LP, Mitchell MB, Truong U. Close look at the Potts shunt flow hemodynamics in a patient with severe pulmonary hypertension: 4D-flow MRI evaluation. J Magn Reson Imaging. 2018 Nov 19. [Epub ahead of print] PubMed PMID: 30451346
  • Schäfer M, Browne LP, Morgan GJ, Barker AJ, Fonseca B, Ivy DD, Mitchell MB. Reduced proximal aortic compliance and elevated wall shear stress after early repair of tetralogy of Fallot. J Thorac Cardiovasc Surg. 2018 Dec;156(6):2239-2249. PubMed PMID: 30449579
  • Schäfer M, Younoszai A, Truong U, Browne LP, Mitchell MB, Jaggers J, Campbell DN, Hunter KS, Ivy DD, Di Maria MV. Influence of aortic stiffness on ventricular function in patients with Fontan circulation. J Thorac Cardiovasc Surg. 2018 Oct 5. [Epub ahead of print] PubMed PMID: 30396734
  • Zhu N, Welch CL, Wang J, Allen PM, Gonzaga-Jauregui C, Ma L, King AK, Krishnan U, Rosenzweig EB, Ivy DD, Austin ED, Hamid R, Pauciulo MW, Lutz KA, Nichols WC, Reid JG, Overton JD, Baras A, Dewey FE, Shen Y, Chung WK. Rare variants in SOX17 are associated with pulmonary arterial hypertension with congenital heart disease. Genome Med. 2018 Jul 20;10(1):56. PubMed PMID: 30029678
  • Bush D, Galambos C, Ivy DD, Abman SH, Wolter-Warmerdam K, Hickey F. Clinical Characteristics and Risk Factors for Developing Pulmonary Hypertension in Children with Down Syndrome. J Pediatr. 2018 Nov;202:212-219.e2. PubMed PMID: 30025669
  • Schäfer M, Wilson N, Ivy DD, Ing R, Abman S, Browne LP, Morgan G, Ross M, McLennan D, Barker AJ, Fonseca B, Di Maria M, Hunter KS, Truong U. Noninvasive wave intensity analysis predicts functional worsening in children with pulmonary arterial hypertension. Am J Physiol Heart Circ Physiol. 2018 Oct 1;315(4):H968-H977. PubMed PMID: 30004811
  • Dufva MJ, Truong U, Tiwari P, Ivy DD, Shandas R, Kheyfets VO. Left ventricular torsion rate and the relation to right ventricular function in pediatric pulmonary arterial hypertension. Pulm Circ. 2018 Jul-Sep;8(3):2045894018791352. PubMed PMID: 30003835
  • Friesen RM, Schäfer M, Ivy DD, Abman SH, Stenmark K, Browne LP, Barker AJ, Hunter KS, Truong U. Proximal pulmonary vascular stiffness as a prognostic factor in children with pulmonary arterial hypertension. Eur Heart J Cardiovasc Imaging. 2018 May 16. [Epub ahead of print] PubMed PMID: 29788051
  • Schäfer M, Truong U, Ivy DD, Fonseca B, Malone L, DiMaria M, Barker AJ, Vargas D, Hunter KS, Jone PN, Browne LP. Children with kawasaki disease present elevated stiffness of great arteries: Phase-contrast MRI study. J Magn Reson Imaging. 2018 Apr 29. [Epub ahead of print] PubMed PMID: 29707843
  • Schäfer M, Browne LP, Truong U, Jaggers JJ, Mitchell MB, Malone L, Morgan G, Chatfield K, McLennan D, Turbendian H, Vargas D, Fonseca B, DiMaria M, Shah A, Ivy MP, Barker AJ, Hunter KS, Wilson N, Ivy DD, Campbell DN. Aortic stiffness in adolescent Turner and Marfan syndrome patients. Eur J Cardiothorac Surg. 2018 Apr 19. [Epub ahead of print] PubMed PMID: 29684119
  • Schäfer M, Morgan GJ, Mitchell MB, Ross M, Barker AJ, Hunter KS, Fonseca B, DiMaria M, Vargas D, Ivy DD, Wilson N, Browne LP. Impact of different coarctation therapies on aortic stiffness: phase-contrast MRI study. Int J Cardiovasc Imaging. 2018 Sep;34(9):1459-1469. PubMed PMID: 29667078
  • Rosenzweig EB, Abman SH, Adatia I, Beghetti M, Bonnet D, Haworth S, Ivy DD, Berger RMF. Paediatric pulmonary arterial hypertension: updates on definition, classification, diagnostics and management. Eur Respir J. 2018 Dec 13. [Epub ahead of print] PubMed PMID: 30545978
  • Rhodes CJ, Batai K, Bleda M, Haimel M, Southgate L, Germain M, Pauciulo MW, Hadinnapola C, Aman J, Girerd B, Arora A, Knight J, Hanscombe KB, Karnes JH, Kaakinen M, Gall H, Ulrich A, Harbaum L, Cebola I, Ferrer J, Lutz K, Swietlik EM, Ahmad F, Amouyel P, Archer SL, Argula R, Austin ED, Badesch D, Bakshi S, Barnett C, Benza R, Bhatt N, Bogaard HJ, Burger CD, Chakinala M, Church C, Coghlan JG, Condliffe R, Corris PA, Danesino C, Debette S, Elliott CG, Elwing J, Eyries M, Fortin T, Franke A, Frantz RP, Frost A, Garcia JGN, Ghio S, Ghofrani HA, Gibbs JSR, Harley J, He H, Hill NS, Hirsch R, Houweling AC, Howard LS, Ivy D, Kiely DG, Klinger J, Kovacs G, Lahm T, Laudes M, Machado RD, Ross RVM, Marsolo K, Martin LJ, Moledina S, Montani D, Nathan SD, Newnham M, Olschewski A, Olschewski H, Oudiz RJ, Ouwehand WH, Peacock AJ, Pepke-Zaba J, Rehman Z, Robbins I, Roden DM, Rosenzweig EB, Saydain G, Scelsi L, Schilz R, Seeger W, Shaffer CM, Simms RW, Simon M, Sitbon O, Suntharalingam J, Tang H, Tchourbanov AY, Thenappan T, Torres F, Toshner MR, Treacy CM, Noordegraaf AV, Waisfisz Q, Walsworth AK, Walter RE, Wharton J, White RJ, Wilt J, Wort SJ, Yung D, Lawrie A, Humbert M, Soubrier F, Trégouët DA, Prokopenko I, Kittles R, Gräf S, Nichols WC, Trembath RC, Desai AA, Morrell NW, Wilkins MR. Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis. Lancet Respir Med. 2018 Dec 5. [Epub ahead of print] PubMed PMID: 30527956
  • Zhu N, Gonzaga-Jauregui C, Welch CL, Ma L, Qi H, King AK, Krishnan U, Rosenzweig EB, Ivy DD, Austin ED, Hamid R, Nichols WC, Pauciulo MW, Lutz KA, Sawle A, Reid JG, Overton JD, Baras A, Dewey F, Shen Y, Chung WK. Exome Sequencing in Children With Pulmonary Arterial Hypertension Demonstrates Differences Compared With Adults. Circ Genom Precis Med. 2018 Apr;11(4):e001887. PubMed PMID: 29631995
  • Kinsella JP, Steinhorn RH, Mullen MP, Hopper RK, Keller RL, Ivy DD, Austin ED, Krishnan US, Rosenzweig EB, Fineman JR, Everett AD, Hanna BD, Humpl T, Raj JU, Abman SH. The Left Ventricle in Congenital Diaphragmatic Hernia: Implications for the Management of Pulmonary Hypertension. J Pediatr. 2018 Jun;197:17-22. PubMed PMID: 29628412
  • Frank BS, Ivy DD. Diagnosis, Evaluation and Treatment of Pulmonary Arterial Hypertension in Children. Children (Basel). 2018 Mar 23;5(4). PubMed PMID: 29570688
  • Lee WS, Wong SY, Ivy DD, Sokol RJ. Hepatopulmonary Syndrome and Portopulmonary Hypertension in Children: Recent Advances in Diagnosis and Management. J Pediatr. 2018 May;196:14-21.e1. PubMed PMID: 29514741
  • Schäfer M, Collins KK, Browne LP, Ivy DD, Abman S, Friesen R, Frank B, Fonseca B, DiMaria M, Hunter KS, Truong U, von Alvensleben JC. Effect of electrical dyssynchrony on left and right ventricular mechanics in children with pulmonary arterial hypertension. J Heart Lung Transplant. 2018 Jul;37(7):870-878. PubMed PMID: 29496397
  • Liptzin DR, Abman SH, Giesenhagen A, Ivy DD. An Approach to Children with Pulmonary Edema at High Altitude. High Alt Med Biol. 2018 Mar;19(1):91-98. PubMed PMID: 29470103
  • Torok RD, Li JS, Kannankeril PJ, Atz AM, Bishai R, Bolotin E, Breitenstein S, Chen C, Diacovo T, Feltes T, Furlong P, Hanna M, Graham EM, Hsu D, Ivy DD, Murphy D, Kammerman LA, Kearns G, Lawrence J, Lebeaut B, Li D, Male C, McCrindle B, Mugnier P, Newburger JW, Pearson GD, Peiris V, Percival L, Pina M, Portman R, Shaddy R, Stockbridge NL, Temple R, Hill KD. Recommendations to Enhance Pediatric Cardiovascular Drug Development: Report of a Multi-Stakeholder Think Tank. J Am Heart Assoc. 2018 Feb 10;7(4). PubMed PMID: 29440007
  • Di Maria MV, Mulvahill M, Jaggers J, Ivy DD, Younoszai AK. Predictive value of presuperior cavopulmonary anastomosis cardiac catheterization at increased altitude. Congenit Heart Dis. 2018 Mar;13(2):311-318. PubMed PMID: 29431283
  • Schäfer M, Truong U, Browne LP, Morgan GJ, Ross M, Ing R, Hunter KS, Kheyfets VO, Abman SH, Ivy DD, Wilson N. Measuring Flow Hemodynamic Indices and Oxygen Consumption in Children with Pulmonary Hypertension: A Comparison of Catheterization and Phase-Contrast MRI. Pediatr Cardiol. 2017 Oct 17. [Epub ahead of print] PubMed PMID: 29043395
  • Friesen RM, Schäfer M, Burkett DA, Cassidy CJ, Ivy DD, Jone PN. Right Ventricular Tissue Doppler Myocardial Performance Index in Children with Pulmonary Hypertension: Relation to Invasive Hemodynamics. Pediatr Cardiol. 2017 Oct 4. [Epub ahead of print] PubMed PMID: 28980052
  • Jone PN, Schäfer M, Pan Z, Bremen C, Ivy DD. 3D echocardiographic evaluation of right ventricular function and strain: a prognostic study in paediatric pulmonary hypertension. Eur Heart J Cardiovasc Imaging. 2017 Aug 25. [Epub ahead of print] PubMed PMID: 28950335
  • Colvin KL, Ivy DD, Yeager ME. Altered Peripheral Blood Myeloid Cell Subpopulations in Children With Down Syndrome and Pulmonary Hypertension. J Pediatr Hematol Oncol. 2017 Jan 5. [Epub ahead of print] PubMed PMID: 28060127
  • Schäfer M, Truong U, Browne LP, Morgan GJ, Ross M, Ing R, Hunter KS, Kheyfets VO, Abman SH, Ivy DD, Wilson N. Measuring Flow Hemodynamic Indices and Oxygen Consumption in Children with Pulmonary Hypertension: A Comparison of Catheterization and Phase-Contrast MRI. Pediatr Cardiol. 2017 Oct 17. [Epub ahead of print] PubMed PMID: 29043395
  • Friesen RM, Schäfer M, Burkett DA, Cassidy CJ, Ivy DD, Jone PN. Right Ventricular Tissue Doppler Myocardial Performance Index in Children with Pulmonary Hypertension: Relation to Invasive Hemodynamics. Pediatr Cardiol. 2017 Oct 4. [Epub ahead of print] PubMed PMID: 28980052
  • Jone PN, Schäfer M, Pan Z, Bremen C, Ivy DD. 3D echocardiographic evaluation of right ventricular function and strain: a prognostic study in paediatric pulmonary hypertension. Eur Heart J Cardiovasc Imaging. 2017 Aug 25. [Epub ahead of print] PubMed PMID: 28950335
  • Kheyfets VO, Sucharov CC, Truong U, Dunning J, Hunter K, Ivy D, Miyamoto S, Shandas R. Circulating miRNAs in Pediatric Pulmonary Hypertension Show Promise as Biomarkers of Vascular Function. Oxid Med Cell Longev. 2017;2017:4957147. PubMed PMID: 28819545
  • Sable CA, Ivy DD, Beekman RH 3rd, Clayton-Jeter HD, Jenkins KJ, Mahle WT, Morrow WR, Murphy MD, Nelson RM, Rosenthal GL, Stockbridge N, Wessel DL. 2017 ACC/AAP/AHA Health Policy Statement on Opportunities and Challenges in Pediatric Drug Development: Learning From Sildenafil. J Am Coll Cardiol. 2017 Jul 25;70(4):495-503. PubMed PMID: 28669447
  • Sable CA, Ivy DD, Beekman RH 3rd, Clayton-Jeter HD, Jenkins KJ, Mahle WT, Morrow WR, Murphy MD, Nelson RM, Rosenthal GL, Stockbridge N, Wessel DL. 2017 ACC/AAP/AHA Health Policy Statement on Opportunities and Challenges in Pediatric Drug Development: Learning From Sildenafil. Circ Cardiovasc Qual Outcomes. 2017 Jul;10(7). PubMed PMID: 28663437
  • Krishnan U, Feinstein JA, Adatia I, Austin ED, Mullen MP, Hopper RK, Hanna B, Romer L, Keller RL, Fineman J, Steinhorn R, Kinsella JP, Ivy DD, Rosenzweig EB, Raj U, Humpl T, Abman SH. Evaluation and Management of Pulmonary Hypertension in Children with Bronchopulmonary Dysplasia. J Pediatr. 2017 Sep;188:24-34.e1. PubMed PMID: 28645441
  • Parker DK, Shen S, Zheng J, Ivy DD, Crotwell DN, Hotz JC, DiBlasi RM. Inhaled Treprostinil Drug Delivery During Mechanical Ventilation and Spontaneous Breathing Using Two Different Nebulizers. Pediatr Crit Care Med. 2017 Jun;18(6):e253-e260. PubMed PMID: 28441181
  • Berger RMF, Gehin M, Beghetti M, Ivy D, Kusic-Pajic A, Cornelisse P, Grill S, Bonnet D. A bosentan pharmacokinetic study to investigate dosing regimens in paediatric patients with pulmonary arterial hypertension: FUTURE-3. Br J Clin Pharmacol. 2017 Aug;83(8):1734-1744. PubMed PMID: 28213957
  • Schäfer M, Ivy DD, Abman SH, Barker AJ, Browne LP, Fonseca B, Kheyfets V, Hunter KS, Truong U. Apparent Aortic Stiffness in Children With Pulmonary Arterial Hypertension: Existence of Vascular Interdependency?. Circ Cardiovasc Imaging. 2017 Feb;10(2). PubMed PMID: 28193613
  • Zijlstra WM, Elmasry O, Pepplinkhuizen S, Ivy DD, Bonnet D, Luijendijk P, Lévy M, Gavilan JL, Torrent-Vernetta A, Mendoza A, Del Cerro MJ, Moledina S, Berger RM. Pulmonary arterial hypertension in children after neonatal arterial switch operation. Heart. 2017 Aug;103(16):1244-1249. PubMed PMID: 28115472
  • Colvin KL, Ivy DD, Yeager ME. Altered Peripheral Blood Myeloid Cell Subpopulations in Children With Down Syndrome and Pulmonary Hypertension. J Pediatr Hematol Oncol. 2017 Jan 5. [Epub ahead of print] PubMed PMID: 28060127
  • Humpl T, Berger RM, Austin ED, Fasnacht Boillat MS, Bonnet D, Ivy DD, Zuk M, Beghetti M, Schulze-Neick I. Treatment initiation in paediatric pulmonary hypertension: insights from a multinational registry. Cardiol Young. 2016 Dec 20;:1-10. [Epub ahead of print] PubMed PMID: 27995825
  • Patel SS, Fernie JC, Taylor AL, Ivy DD, Rausch CM. Evaluation of predictive models for six minute walk test among children with pulmonary hypertension. Int J Cardiol. 2016 Nov 7. [Epub ahead of print] PubMed PMID: 27838122
  • Clopton RG, Friesen R, Partrick D, Wilson N, Jaggers J, Ivy DD, Schwartz LI, Ing RJ. The Anesthetic Challenges of Lung Biopsy-Associated Intrathoracic Hemorrhage in a Child With Suprasystemic Pulmonary Hypertension. Semin Cardiothorac Vasc Anesth. 2016 Nov 3. [Epub ahead of print] PubMed PMID: 27815350
  • Takatsuki S, Nakayama T, Ikehara S, Matsuura H, Ivy DD, Saji T. Pulmonary Arterial Capacitance Index Is a Strong Predictor for Adverse Outcome in Children with Idiopathic and Heritable Pulmonary Arterial Hypertension. J Pediatr. 2016 Oct 31. [Epub ahead of print] PubMed PMID: 27810156
  • Hauck A, Guo R, Ivy DD, Younoszai A. Tricuspid annular plane systolic excursion is preserved in young patients with pulmonary hypertension except when associated with repaired congenital heart disease. Eur Heart J Cardiovasc Imaging. 2016 Apr 20. [Epub ahead of print] PubMed PMID: 27099276
  • Schäfer M, Ivy DD, Barker AJ, Kheyfets V, Shandas R, Abman SH, Hunter KS, Truong U. Characterization of CMR-derived haemodynamic data in children with pulmonary arterial hypertension. Eur Heart J Cardiovasc Imaging. 2016 Jul 21. [Epub ahead of print] PubMed PMID: 27444679
  • Jone PN, Schäfer M, Li L, Craft M, Ivy DD, Kutty S. Right Atrial Deformation in Predicting Outcomes in Pediatric Pulmonary Hypertension. Circ Cardiovasc Imaging. 2017 Dec;10(12). PubMed PMID: 29233835
  • Abman SH, Ivy DD, Archer SL, Wilson K. Executive Summary of the American Heart Association and American Thoracic Society Joint Guidelines for Pediatric Pulmonary Hypertension. Am J Respir Crit Care Med. 2016 Oct 1;194(7):898-906. PubMed PMID: 27689707
  • Kheyfets VO, Dunning J, Truong U, Ivy D, Hunter K, Shandas R. A 0-D Model and Protocol for Simulating Patient Specific Pulmonary Hemodynamics from Limited Clinical Data. J Biomech Eng. 2016 Sep 29. [Epub ahead of print] PubMed PMID: 27684888
  • Zijlstra WM, Douwes JM, Ploegstra MJ, Krishnan U, Roofthooft MT, Hillege HL, Ivy DD, Rosenzweig EB, Berger RM. Clinical classification in pediatric pulmonary arterial hypertension associated with congenital heart disease. Pulm Circ. 2016 Sep;6(3):302-12. PubMed PMID: 27683607
  • Berger RM, Haworth SG, Bonnet D, Dulac Y, Fraisse A, Galiè N, Ivy DD, Jaïs X, Miera O, Rosenzweig EB, Efficace M, Kusic-Pajic A, Beghetti M. Corrigendum to "FUTURE-2: Results from an open-label, long-term safety and tolerability extension study using the pediatric FormUlation of bosenTan in pUlmonary arterial hypeRtEnsion" [Int. J. Cardiol. 202 (2016) 52-58]. Int J Cardiol. 2016 Aug 24. [Epub ahead of print] PubMed PMID: 27623401
  • Burkett DA, Slorach C, Patel SS, Redington AN, Ivy DD, Mertens L, Younoszai AK, Friedberg MK. Impact of Pulmonary Hemodynamics and Ventricular Interdependence on Left Ventricular Diastolic Function in Children With Pulmonary Hypertension. Circ Cardiovasc Imaging. 2016 Sep;9(9). PubMed PMID: 27581953
  • Schäfer M, Ivy DD, Barker AJ, Kheyfets V, Shandas R, Abman SH, Hunter KS, Truong U. Characterization of CMR-derived haemodynamic data in children with pulmonary arterial hypertension. Eur Heart J Cardiovasc Imaging. 2016 Jul 21. [Epub ahead of print] PubMed PMID: 27444679
  • Ivy D. Pulmonary Hypertension in Children. Cardiol Clin. 2016 Aug;34(3):451-72. PubMed PMID: 27443141
  • Yang J, Nies MK, Fu Z, Damico R, Korley FK, Hassoun PM, Ivy DD, Austin ED, Everett AD. Hepatoma Derived Growth Factor Predicts Disease Severity and Survival in Pulmonary Artery Hypertension. Am J Respir Crit Care Med. 2016 Jun 2. [Epub ahead of print] PubMed PMID: 27254543
  • Del Cerro MJ, Moledina S, Haworth SG, Ivy D, Al Dabbagh M, Banjar H, Diaz G, Heath-Freudenthal A, Galal AN, Humpl T, Kulkarni S, Lopes A, Mocumbi AO, Puri GD, Rossouw B, Harikrishnan S, Saxena A, Udo P, Caicedo L, Tamimi O, Adatia I. Cardiac catheterization in children with pulmonary hypertensive vascular disease: consensus statement from the Pulmonary Vascular Research Institute, Pediatric and Congenital Heart Disease Task Forces. Pulm Circ. 2016 Mar;6(1):118-25. PubMed PMID: 27076908
  • Ploegstra MJ, Ivy DD, Wheeler JG, Brand M, Beghetti M, Rosenzweig EB, Humpl T, Iriart X, Rouzic EM, Bonnet D, Berger RM. Growth in children with pulmonary arterial hypertension: a longitudinal retrospective multiregistry study. Lancet Respir Med. 2016 Apr;4(4):281-90. PubMed PMID: 26994897
  • Douwes JM, Humpl T, Bonnet D, Beghetti M, Ivy DD, Berger RM. Acute Vasodilator Response in Pediatric Pulmonary Arterial Hypertension: Current Clinical Practice From the TOPP Registry. J Am Coll Cardiol. 2016 Mar 22;67(11):1312-23. PubMed PMID: 26988953
  • Kim JS, McSweeney J, Lee J, Ivy D. Pediatric Cardiac Intensive Care Society 2014 Consensus Statement: Pharmacotherapies in Cardiac Critical Care Pulmonary Hypertension. Pediatr Crit Care Med. 2016 Mar;17(3 Suppl 1):S89-100. PubMed PMID: 26945333
  • Beghetti M, Berger RM, Ivy DD, Bonnet D, Humpl T. To "Cath" or Not in Pediatric Pulmonary Hypertension?. J Am Coll Cardiol. 2016 Mar 1;67(8):1010-1. PubMed PMID: 26916495
  • Jone PN, Patel SS, Cassidy C, Ivy DD. Three-dimensional Echocardiography of Right Ventricular Function Correlates with Severity of Pediatric Pulmonary Hypertension. Congenit Heart Dis. 2016 Feb 22. [Epub ahead of print] PubMed PMID: 26899626
  • Hopper RK, Abman SH, Ivy DD. Persistent Challenges in Pediatric Pulmonary Hypertension. Chest. 2016 Jul;150(1):226-36. PubMed PMID: 26836930
  • Kinsella JP, Steinhorn RH, Krishnan US, Feinstein JA, Adatia I, Austin ED, Rosenzweig EB, Everett AD, Fineman JR, Hanna BD, Hopper RK, Humpl T, Ivy DD, Keller RL, Mullen MP, Raj JU, Wessel DL, Abman SH. Recommendations for the Use of Inhaled Nitric Oxide Therapy in Premature Newborns with Severe Pulmonary Hypertension. J Pediatr. 2015 Dec 15. [Epub ahead of print] PubMed PMID: 26703869
  • Patel SS, Fernie JC, Taylor AL, Ivy DD, Rausch CM. Evaluation of predictive models for six minute walk test among children with pulmonary hypertension. Int J Cardiol. 2016 Nov 7. [Epub ahead of print] PubMed PMID: 27838122
  • Clopton RG, Friesen R, Partrick D, Wilson N, Jaggers J, Ivy DD, Schwartz LI, Ing RJ. The Anesthetic Challenges of Lung Biopsy-Associated Intrathoracic Hemorrhage in a Child With Suprasystemic Pulmonary Hypertension. Semin Cardiothorac Vasc Anesth. 2016 Nov 3. [Epub ahead of print] PubMed PMID: 27815350
  • Takatsuki S, Nakayama T, Ikehara S, Matsuura H, Ivy DD, Saji T. Pulmonary Arterial Capacitance Index Is a Strong Predictor for Adverse Outcome in Children with Idiopathic and Heritable Pulmonary Arterial Hypertension. J Pediatr. 2016 Oct 31. [Epub ahead of print] PubMed PMID: 27810156
  • Hauck A, Guo R, Ivy DD, Younoszai A. Tricuspid annular plane systolic excursion is preserved in young patients with pulmonary hypertension except when associated with repaired congenital heart disease. Eur Heart J Cardiovasc Imaging. 2016 Apr 20. [Epub ahead of print] PubMed PMID: 27099276
  • Humpl T, Berger RM, Austin ED, Fasnacht Boillat MS, Bonnet D, Ivy DD, Zuk M, Beghetti M, Schulze-Neick I. Treatment initiation in paediatric pulmonary hypertension: insights from a multinational registry. Cardiol Young. 2016 Dec 20;:1-10. [Epub ahead of print] PubMed PMID: 27995825
  • Beghetti M, Schulze-Neick I, Berger RM, Ivy DD, Bonnet D, Weintraub RG, Saji T, Yung D, Mallory GB, Geiger R, Berger JT, Barst RJ, Humpl T. Haemodynamic characterisation and heart catheterisation complications in children with pulmonary hypertension: Insights from the Global TOPP Registry (tracking outcomes and practice in paediatric pulmonary hypertension). Int J Cardiol. 2016 Jan 15;203:325-30. PubMed PMID: 26583838
  • Friesen RH, Twite MD, Nichols CS, Cardwell KA, Pan Z, Darst JR, Wilson N, Fagan TE, Miyamoto SD, Ivy DD. Hemodynamic response to ketamine in children with pulmonary hypertension. Paediatr Anaesth. 2015 Nov 13. [Epub ahead of print] PubMed PMID: 26564806
  • Berger RM, Haworth SG, Bonnet D, Dulac Y, Fraisse A, Galiè N, Ivy DD, Jaïs X, Miera O, Rosenzweig EB, Efficace M, Kusic-Pajic A, Beghetti M. FUTURE-2: Results from an open-label, long-term safety and tolerability extension study using the pediatric FormUlation of bosenTan in pUlmonary arterial hypeRtEnsion. Int J Cardiol. 2016 Jan 1;202:52-8. PubMed PMID: 26386921
  • Kheyfets VO, Dunning J, Truong U, Ivy DD, Hunter KA, Shandas R. Assessment of N-terminal prohormone B-type natriuretic peptide as a measure of vascular and ventricular function in pediatric pulmonary arterial hypertension. Pulm Circ. 2015 Dec;5(4):658-66. PubMed PMID: 26697173
  • Abman SH, Hansmann G, Archer SL, Ivy DD, Adatia I, Chung WK, Hanna BD, Rosenzweig EB, Raj JU, Cornfield D, Stenmark KR, Steinhorn R, Thébaud B, Fineman JR, Kuehne T, Feinstein JA, Friedberg MK, Earing M, Barst RJ, Keller RL, Kinsella JP, Mullen M, Deterding R, Kulik T, Mallory G, Humpl T, Wessel DL. Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society. Circulation. 2015 Nov 3. [Epub ahead of print] PubMed PMID: 26534956
  • Truong U, Patel S, Kheyfets V, Dunning J, Fonseca B, Barker AJ, Ivy D, Shandas R, Hunter K. Non-invasive determination by cardiovascular magnetic resonance of right ventricular-vascular coupling in children and adolescents with pulmonary hypertension. J Cardiovasc Magn Reson. 2015 Sep 16;17(1):81. PubMed PMID: 26376972
  • Ivy DD, Abman S. Beyond the 6-Minute Walk Test for Assessing Pediatric Pulmonary Hypertension: Making Strides Through Combination End Points. Chest. 2015 Sep;148(3):576-7. PubMed PMID: 26324131
  • Di Maria MV, Burkett DA, Younoszai AK, Landeck BF 2nd, Mertens L, Ivy DD, Friedberg MK, Hunter KS. Echocardiographic Estimation of Right Ventricular Stroke Work in Children with Pulmonary Arterial Hypertension: Comparison with Invasive Measurements. J Am Soc Echocardiogr. 2015 Aug 20. [Epub ahead of print] PubMed PMID: 26299333
  • Burkett DA, Slorach C, Patel SS, Redington AN, Ivy DD, Mertens L, Younoszai AK, Friedberg MK. Left Ventricular Myocardial Function in Children With Pulmonary Hypertension: Relation to Right Ventricular Performance and Hemodynamics. Circ Cardiovasc Imaging. 2015 Aug;8(8). PubMed PMID: 26259580
  • Abman SH, Ivy DD. Hospitalizations of Children With Pulmonary Hypertension: Implications for Improving Care. Pediatrics. 2015 Aug;136(2):392-3. PubMed PMID: 26148953
  • Rosenkranz S, Ghofrani HA, Beghetti M, Ivy D, Frey R, Fritsch A, Weimann G, Saleh S, Apitz C. Riociguat for pulmonary arterial hypertension associated with congenital heart disease. Heart. 2015 Nov 15;101(22):1792-9. PubMed PMID: 26135803
  • Webber SA, Hsu DT, Ivy DD, Kulik TJ, Pahl E, Rosenthal DN, Morrow WR, Feinstein JA. Task Force 7: Pediatric Cardiology Fellowship Training in Pulmonary Hypertension, Advanced Heart Failure, and Transplantation. J Am Coll Cardiol. 2015 Aug 11;66(6):732-9. PubMed PMID: 25777654
  • Ross RD, Brook M, Feinstein JA, Koenig P, Lang P, Spicer R, Vincent JA, Lewis AB, Martin GR, Bartz PJ, Fischbach PS, Fulton DR, Matherne GP, Reinking B, Srivastava S, Printz B, Geva T, Shirali GS, Weinberg P, Wong PC, Armsby LB, Vincent RN, Foerster SR, Holzer RJ, Moore JW, Marshall AC, Latson L, Dubin AM, Walsh EP, Franklin W, Kanter RJ, Saul JP, Shah MJ, Van Hare GF, Feltes TF, Roth SJ, Almodovar MC, Andropoulos DB, Bohn DJ, Costello JM, Gajarski RJ, Mott AR, Stout K, Valente AM, Cook S, Gurvitz M, Saidi A, Webber SA, Hsu DT, Ivy DD, Kulik TJ, Pahl E, Rosenthal DN, Morrow R, Mahle WT, Murphy AM, Li JS, Law YM, Newburger JW, Daniels SR, Bernstein D, Marino BS. 2015 SPCTPD/ACC/AAP/AHA Training Guidelines for Pediatric Cardiology Fellowship Programs (Revision of the 2005 Training Guidelines for Pediatric Cardiology Fellowship Programs). J Am Coll Cardiol. 2015 Mar 13. [Epub ahead of print] PubMed PMID: 25777637
  • Webber SA, Hsu DT, Ivy DD, Kulik TJ, Pahl E, Rosenthal DN, Morrow WR, Feinstein JA. Task Force 7: Pediatric Cardiology Fellowship Training in Pulmonary Hypertension, Advanced Heart Failure, and Transplantation. SPCTPD/ACC/AAP/AHA. Circulation. 2015 Aug 11;132(6):e99-e106. PubMed PMID: 25769631
  • Ivy DD, Abman SH. Gaining Insights into Pediatric Pulmonary Hypertensive Disorders through Patient Registries. Am J Respir Crit Care Med. 2015 Jan 1;191(1):2-4. PubMed PMID: 25551339
  • Jone PN, Bremen C, DiMaria M, Campbell DN, Jaggers J, Younoszai A, Ivy DD. Three-Dimensional Echocardiography Enhances Diagnostic Accuracy of Supramitral Ring. Echocardiography. 2014 Dec 12. [Epub ahead of print] PubMed PMID: 25496227
  • Kinsella JP, Steinhorn RH, Krishnan US, Feinstein JA, Adatia I, Austin ED, Rosenzweig EB, Everett AD, Fineman JR, Hanna BD, Hopper RK, Humpl T, Ivy DD, Keller RL, Mullen MP, Raj JU, Wessel DL, Abman SH. Recommendations for the Use of Inhaled Nitric Oxide Therapy in Premature Newborns with Severe Pulmonary Hypertension. J Pediatr. 2015 Dec 15. [Epub ahead of print] PubMed PMID: 26703869
  • Barst RJ, Ivy DD, Foreman AJ, McGoon MD, Rosenzweig EB. Four- and seven-year outcomes of patients with congenital heart disease-associated pulmonary arterial hypertension (from the REVEAL Registry). Am J Cardiol. 2014 Jan 1;113(1):147-55. PubMed PMID: 24176071
  • Krishnan U, Takatsuki S, Ivy DD, Kerstein J, Calderbank M, Coleman E, Rosenzweig EB. Effectiveness and safety of inhaled treprostinil for the treatment of pulmonary arterial hypertension in children. Am J Cardiol. 2012 Dec 1;110(11):1704-9. PubMed PMID: 22917554
  • Yeager ME, Reddy MB, Nguyen CM, Colvin KL, Ivy DD, Stenmark KR. Activation of the unfolded protein response is associated with pulmonary hypertension. Pulm Circ. 2012 Apr-Jun;2(2):229-40. PubMed PMID: 22837864
  • Barst RJ, Channick R, Ivy D, Goldstein B. Clinical perspectives with long-term pulsed inhaled nitric oxide for the treatment of pulmonary arterial hypertension. Pulm Circ. 2012 Apr-Jun;2(2):139-47. PubMed PMID: 22837854
  • Takatsuki S, Nakayama T, Jone PN, Wagner BD, Naoi K, Ivy DD, Saji T. Tissue Doppler imaging predicts adverse outcome in children with idiopathic pulmonary arterial hypertension. J Pediatr. 2012 Dec;161(6):1126-31. PubMed PMID: 22748515
  • Yeager ME, Colvin KL, Everett AD, Stenmark KR, Ivy DD. Plasma proteomics of differential outcome to long-term therapy in children with idiopathic pulmonary arterial hypertension. Proteomics Clin Appl. 2012 Jun;6(5-6):257-67. PubMed PMID: 22653875
  • Takatsuki S, Darst JR, Das BB, Fagan TE, Wolfe R, Ivy DD. Clinical manifestations and long-term follow-up in pediatric patients living at altitude with isolated pulmonary artery of ductal origin. Pediatr Cardiol. 2012 Jun;33(5):775-81. PubMed PMID: 22430374
  • Takatsuki S, Calderbank M, Ivy DD. Initial experience with tadalafil in pediatric pulmonary arterial hypertension. Pediatr Cardiol. 2012 Jun;33(5):683-8. PubMed PMID: 22402804
  • Stoica S, Carpenter E, Campbell D, Mitchell M, da Cruz E, Ivy D, Lacour-Gayet F. Morbidity of the arterial switch operation. Ann Thorac Surg. 2012 Jun;93(6):1977-83. PubMed PMID: 22365263
  • Takatsuki S, Wagner BD, Ivy DD. B-type natriuretic peptide and amino-terminal pro-B-type natriuretic peptide in pediatric patients with pulmonary arterial hypertension. Congenit Heart Dis. 2012 May-Jun;7(3):259-67. PubMed PMID: 22325151
  • Ivy D. Advances in pediatric pulmonary arterial hypertension. Curr Opin Cardiol. 2012 Mar;27(2):70-81. PubMed PMID: 22274573
  • Berger RM, Beghetti M, Humpl T, Raskob GE, Ivy DD, Jing ZC, Bonnet D, Schulze-Neick I, Barst RJ. Clinical features of paediatric pulmonary hypertension: a registry study. Lancet. 2012 Feb 11;379(9815):537-46. PubMed PMID: 22240409
  • Feinstein JA, Benson DW, Dubin AM, Cohen MS, Maxey DM, Mahle WT, Pahl E, Villafañe J, Bhatt AB, Peng LF, Johnson BA, Marsden AL, Daniels CJ, Rudd NA, Caldarone CA, Mussatto KA, Morales DL, Ivy DD, Gaynor JW, Tweddell JS, Deal BJ, Furck AK, Rosenthal GL, Ohye RG, Ghanayem NS, Cheatham JP, Tworetzky W, Martin GR. Hypoplastic left heart syndrome: current considerations and expectations. J Am Coll Cardiol. 2012 Jan 3;59(1 Suppl):S1-42. PubMed PMID: 22192720
  • Barst RJ, Ivy DD, Gaitan G, Szatmari A, Rudzinski A, Garcia AE, Sastry BK, Pulido T, Layton GR, Serdarevic-Pehar M, Wessel DL. A randomized, double-blind, placebo-controlled, dose-ranging study of oral sildenafil citrate in treatment-naive children with pulmonary arterial hypertension. Circulation. 2012 Jan 17;125(2):324-34. PubMed PMID: 22128226
  • Barst RJ, McGoon MD, Elliott CG, Foreman AJ, Miller DP, Ivy DD. Survival in childhood pulmonary arterial hypertension: insights from the registry to evaluate early and long-term pulmonary arterial hypertension disease management. Circulation. 2012 Jan 3;125(1):113-22. PubMed PMID: 22086881
  • Takatsuki S, Ivy DD, Nuss R. Correlation of N-terminal fragment of B-type natriuretic peptide levels with clinical, laboratory, and echocardiographic abnormalities in children with sickle cell disease. J Pediatr. 2012 Mar;160(3):428-433.e1. PubMed PMID: 22048047
  • Yeager ME, Nguyen CM, Belchenko DD, Colvin KL, Takatsuki S, Ivy DD, Stenmark KR. Circulating myeloid-derived suppressor cells are increased and activated in pulmonary hypertension. Chest. 2012 Apr;141(4):944-52. PubMed PMID: 21940769
  • Yeager ME, Belchenko DD, Nguyen CM, Colvin KL, Ivy DD, Stenmark KR. Endothelin-1, the unfolded protein response, and persistent inflammation: role of pulmonary artery smooth muscle cells. Am J Respir Cell Mol Biol. 2012 Jan;46(1):14-22. PubMed PMID: 21778413
  • Yeager ME, Nguyen CM, Belchenko DD, Colvin KL, Takatsuki S, Ivy DD, Stenmark KR. Circulating fibrocytes are increased in children and young adults with pulmonary hypertension. Eur Respir J. 2012 Jan;39(1):104-11. PubMed PMID: 21700605
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Professional Memberships

  • Congenital Heart Disease: Clinical Studies from Fetus to Adulthood, Editorial Board Member
  • American Collge of Cardiology (ACC), Fellow
  • American Academy of Pediatrics (AAP), Fellow
  • Association for European Paediatric Cardiology (AEPC), Member
  • Pulmonary Hypertension Association (PHA), Board of Trustees
  • Pulmonary Hypertension Association (PHA), Scientific Leadership Council
  • American College of Chest Physicians, Fellow
  • Pediatric Cardiac Intensive Care Society (PCICS), Member
  • American Physiological Society (APS), Member
  • Society For Pediatric Research (SPR), Member
  • Pediatric Congenital Heart Association (PCHA), Board Member
  • American Heart Association (AHA), Fellow

Practice Locations

Children's Hospital Colorado
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation
  • Children's Hospital Colorado
  • University of Colorado Hospital

Specialty Information

Specialties
  • Pediatrics, Board Certification
  • Pediatric Cardiology, Board Certification
Conditions & Treatments
  • Heart and Circulation - Congenital Heart Disease
  • Lungs and Breathing - Pulmonary Hypertension
  • Altitude Medicine
  • Heart and Circulation
  • Lungs and Breathing
Clinical Interest for Patients
I am interested in pulmonary hypertension, cardiac intensive care, and congenital heart disease.

General Information

Medical Schools:
  • MD, Tulane University School of Medicine (1988)
Undergraduate Schools:
  • BS, Davidson College (NC) (1984)
Internships:
  • University of Colorado (Children's Hospital Colorado) Program (1989)
Residency Programs:
  • University of Colorado (Children's Hospital Colorado) Program, Pediatrics (1991)
Fellowships:
  • University of Colorado (Children's Hospital Colorado) Program, Pediatric Cardiology (1994)
Download CV
Languages: English
Department: Pediatrics-Cardiology
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