Leslie Berstein Investigator Development Award, AAFPRS
(2015)
American Rhinologic Society Fall Film FESStival Finalist, American Rhinologic Society
(2014)
Research International Travel Award, ERS-ARS
(2014)
ENT Research Day Outstanding Resident Research Presentation, University of Colorado
(2013)
Research Interests
My research focuses on Inflammatory mechanisms of chronic rhinosinusitis, nasal polyps, Microbiology of chronic sinusitis in unique patient populations, Minimally-invasive surgical techniques for sinus, orbit, and skull base surgery
Teaching
Assistant Professor
(2010)
School of Medicine,
Otolaryngology
Associate Professor
(2016)
School of Medicine,
Otolaryngology
Publications
Schlosser RJ, Smith TL, Mace JC, Alt J, Beswick DM, Mattos JL, Payne S, Ramakrishnan VR, Soler ZM. Factors driving olfactory loss in patients with chronic rhinosinusitis: a case control study. Int Forum Allergy Rhinol. 2020 Jan;10(1):7-14. PubMed PMID: 31899859
Padmakumar V, Ramesh Kumar E, Ramakrishnan VR. A Prospective Study on Temporal Bone Involvement in Polytrauma Patients and the Effect of Early Diagnosis on Hearing Loss. Indian J Otolaryngol Head Neck Surg. 2020 Mar;72(1):30-35. PubMed PMID: 32158652
Orlandi RR, Kingdom TT, Smith TL, Bleier B, DeConde A, Luong A, Poetker DM, Soler Z, Welch KC, Wise SK, Adappa N, Alt JA, Anselmo-Lima WT, Bachert C, Baroody FM, Batra PS, Bernal-Sprekelsen M, Beswick D, Bhattacharyya N, Chandra RK, Chang E, Chiu A, Chowdhury N, Citardi MJ, Cohen NA, Conley DB, DelGaudio J, Desrosiers M, Douglas R, Eloy JA, Fokkens WJ, Gray ST, Gudis DA, Hamilos DL, Han JK, Harvey R, Hellings P, Holbrook EH, Hopkins C, Hwang P, Javer AR, Jiang RS, Kennedy D, Kern R, Laidlaw T, Lal D, Lane A, Lee HM, Lee JT, Levy JM, Lin SY, Lund V, McMains KC, Metson R, Mullol J, Naclerio R, Oakley G, Otori N, Palmer JN, Parikh SR, Passali D, Patel Z, Peters A, Philpott C, Psaltis AJ, Ramakrishnan VR, Ramanathan M Jr, Roh HJ, Rudmik L, Sacks R, Schlosser RJ, Sedaghat AR, Senior BA, Sindwani R, Smith K, Snidvongs K, Stewart M, Suh J, Tan BK, Turner JH, van Drunen CM, Voegels R, Wang Y, Woodworth BA, Wormald PJ, Wright ED, Yan C, Zhang L, Zhou B. International Consensus Statement on Rhinology and Allergy: Rhinosinusitis. Int Forum Allergy Rhinol. 2020 Nov 24. [Epub ahead of print] PubMed PMID: 33236525
Little RE, Alt JA, Ramakrishnan VR, Platt MP, Schlosser RJ, Storck KA, Soler ZM. Objective sleep measures after endoscopic sinus surgery in patients with chronic rhinosinusitis. Int Forum Allergy Rhinol. 2020 Nov 23. [Epub ahead of print] PubMed PMID: 33226190
Beswick DM, Humphries SM, Balkissoon CD, Vladar EK, Ramakrishnan VR, Lynch DA, Taylor-Cousar JL. Machine learning evaluates improvement in sinus computed tomography opacification with CFTR modulator therapy. Int Forum Allergy Rhinol. 2020 Nov 2. [Epub ahead of print] PubMed PMID: 33140564
Mattos JL, Soler ZM, Schlosser RJ, Mace JC, Alt JA, Ramakrishnan VR, Payne SC, Smith TL, Beswick DM. Olfactory Function After Surgical Treatment of CRS: A Comparison of CRS Patients to Healthy Controls. Am J Rhinol Allergy. 2020 Sep 20;:1945892420960671. [Epub ahead of print] PubMed PMID: 32954837
Little RE, Schlosser RJ, Smith TL, Storck KA, Alt JA, Beswick DM, Mace JC, Mattos JL, Ramakrishnan VR, Soler ZM. Disease control after surgery for chronic rhinosinusitis: prospective, multi-institutional validation of the Sinus Control Test. Int Forum Allergy Rhinol. 2020 Jul 26. [Epub ahead of print] PubMed PMID: 32713106
Beswick DM, Smith TL, Mace JC, Alt JA, Farrell NF, Ramakrishnan VR, Schlosser RJ, Soler ZM. Ethmoid-to-maxillary opacification ratio: a predictor of postoperative olfaction and outcomes in nasal polyposis?. Int Forum Allergy Rhinol. 2020 Jun 18. [Epub ahead of print] PubMed PMID: 32558260
Baxter BD, Larson ED, Feinstein P, Polese AG, Bubak AN, Niemeyer CS, Merle L, Shepherd D, Ramakrishnan VR, Nagel MA, Restrepo D. Transcriptional profiling reveals TRPM5-expressing cells involved in viral infection in the olfactory epithelium. bioRxiv. 2020 May 15. PubMed PMID: 32511400
Youssef AS, Arnone GD, Farell NF, Thompson JA, Ramakrishnan VR, Gubbels S, Cohen-Gadol AA, Cass S, Labib MA. The Combined Endoscopic Endonasal Far Medial and Open Postauricular Transtemporal Approaches As a Lesser Invasive Approach to the Jugular Foramen: Anatomic Morphometric Study With Case Illustration. Oper Neurosurg (Hagerstown). 2020 Sep 15;19(4):471-479. PubMed PMID: 32510567
Humphries SM, Centeno JP, Notary AM, Gerow J, Cicchetti G, Katial RK, Beswick DM, Ramakrishnan VR, Alam R, Lynch DA. Volumetric assessment of paranasal sinus opacification on computed tomography can be automated using a convolutional neural network. Int Forum Allergy Rhinol. 2020 Nov;10(11):1218-1225. PubMed PMID: 32306522
Cho DY, Hunter RC, Ramakrishnan VR. The Microbiome and Chronic Rhinosinusitis. Immunol Allergy Clin North Am. 2020 May;40(2):251-263. PubMed PMID: 32278449
Thomas AJ, Mace JC, Ramakrishnan VR, Alt JA, Mattos JL, Schlosser RJ, Soler ZM, Smith TL. Quality-of-life and olfaction changes observed with short-term medical management of chronic rhinosinusitis. Int Forum Allergy Rhinol. 2020 May;10(5):656-664. PubMed PMID: 32017433
Beswick DM, Ramakrishnan VR. The Utility of Image Guidance in Endoscopic Sinus Surgery: A Narrative Review. JAMA Otolaryngol Head Neck Surg. 2020 Mar 1;146(3):286-290. PubMed PMID: 31917412
Schlosser RJ, Smith TL, Mace JC, Alt J, Beswick DM, Mattos JL, Payne S, Ramakrishnan VR, Soler ZM. Factors driving olfactory loss in patients with chronic rhinosinusitis: a case control study. Int Forum Allergy Rhinol. 2020 Jan;10(1):7-14. PubMed PMID: 31899859
Soler ZM, Yoo F, Schlosser RJ, Mulligan J, Ramakrishnan VR, Beswick DM, Alt JA, Mattos JL, Payne SC, Storck KA, Smith TL. Correlation of mucus inflammatory proteins and olfaction in chronic rhinosinusitis. Int Forum Allergy Rhinol. 2020 Mar;10(3):343-355. PubMed PMID: 31856395
Massey CJ, Diaz Del Valle F, Abuzeid WM, Levy JM, Mueller S, Levine CG, Smith SS, Bleier BS, Ramakrishnan VR. Sample collection for laboratory-based study of the nasal airway and sinuses: a research compendium. Int Forum Allergy Rhinol. 2020 Mar;10(3):303-313. PubMed PMID: 31845512
Loftus C, Schlosser RJ, Smith TL, Alt JA, Ramakrishnan VR, Mattos JL, Mappus E, Storck K, Yoo F, Soler ZM. Olfactory cleft and sinus opacification differentially impact olfaction in chronic rhinosinusitis. Laryngoscope. 2020 Oct;130(10):2311-2318. PubMed PMID: 31603563
Schlosser RJ, Smith TL, Mace JC, Alt JA, Beswick DM, Mattos JL, Ramakrishnan V, Massey C, Soler ZM. The Olfactory Cleft Endoscopy Scale: a multi-institutional validation study in chronic rhinosinusitis. Rhinology. 2020 Oct 2. [Epub ahead of print] PubMed PMID: 33006331
Roland LT, Smith TL, Schlosser RJ, Soler ZM, Peters AT, Laidlaw TM, Bleier BS, Ramakrishnan V, Toskala E, Kennedy DW, Luong AU. Guidance for contemporary use of biologics in management of chronic rhinosinusitis with nasal polyps: discussion from a National Institutes of Health-sponsored workshop. Int Forum Allergy Rhinol. 2020 Sep;10(9):1037-1042. PubMed PMID: 32484603
Soler ZM, Yoo F, Schlosser RJ, Mulligan J, Ramakrishnan VR, Beswick DM, Alt JA, Mattos JL, Payne SC, Storck KA, Smith TL. Correlation of mucus inflammatory proteins and olfaction in chronic rhinosinusitis. Int Forum Allergy Rhinol. 2019 Dec 19. [Epub ahead of print] PubMed PMID: 31856395
Massey CJ, Diaz Del Valle F, Abuzeid WM, Levy JM, Mueller S, Levine CG, Smith SS, Bleier BS, Ramakrishnan VR. Sample collection for laboratory-based study of the nasal airway and sinuses: a research compendium. Int Forum Allergy Rhinol. 2019 Dec 17. [Epub ahead of print] PubMed PMID: 31845512
Loftus C, Schlosser RJ, Smith TL, Alt JA, Ramakrishnan VR, Mattos JL, Mappus E, Storck K, Yoo F, Soler ZM. Olfactory cleft and sinus opacification differentially impact olfaction in chronic rhinosinusitis. Laryngoscope. 2019 Oct 11. [Epub ahead of print] PubMed PMID: 31603563
Vandelaar LJ, Hanson B, Marino M, Yao WC, Luong AU, Arias CA, Ramakrishnan V, Citardi MJ. Analysis of Sinonasal Microbiota in Exacerbations of Chronic Rhinosinusitis Subgroups. OTO Open. 2019 Jul-Sep;3(3):2473974X19875100. PubMed PMID: 31555757
Larson ED, Pathak S, Ramakrishnan VR, Finger TE. A Subset of Olfactory Sensory Neurons Express Forkhead Box J1-Driven eGFP. Chem Senses. 2019 Oct 26;44(9):663-671. PubMed PMID: 31504289
Kennel C, Gould EA, Larson ED, Salcedo E, Vickery T, Restrepo D, Ramakrishnan VR. Differential Expression of Mucins in Murine Olfactory Versus Respiratory Epithelium. Chem Senses. 2019 Sep 7;44(7):511-521. PubMed PMID: 31300812
Beswick DM, Mace JC, Soler ZM, Rudmik L, Alt JA, Smith KA, Detwiller KY, Ramakrishnan VR, Smith TL. Socioeconomic status impacts postoperative productivity loss and health utility changes in refractory chronic rhinosinusitis. Int Forum Allergy Rhinol. 2019 Sep;9(9):1000-1009. PubMed PMID: 31246360
Chen J, Larson ED, Anderson CB, Agarwal P, Frank DN, Kinnamon SC, Ramakrishnan VR. Expression of Bitter Taste Receptors and Solitary Chemosensory Cell Markers in the Human Sinonasal Cavity. Chem Senses. 2019 Sep 7;44(7):483-495. PubMed PMID: 31231752
Vickery TW, Ramakrishnan VR, Suh JD. The Role of Staphylococcus aureus in Patients with Chronic Sinusitis and Nasal Polyposis. Curr Allergy Asthma Rep. 2019 Mar 11;19(4):21. PubMed PMID: 30859336
Ung TH, Yang A, Aref M, Folzenlogen Z, Ramakrishnan V, Youssef AS. Correction to: Preservation of olfaction in anterior midline skull base meningiomas: a comprehensive approach. Acta Neurochir (Wien). 2019 Apr;161(4):737. PubMed PMID: 30806779
Ung TH, Yang A, Aref M, Folzenlogen Z, Ramakrishnan V, Youssef AS. Preservation of olfaction in anterior midline skull base meningiomas: a comprehensive approach. Acta Neurochir (Wien). 2019 Apr;161(4):729-735. PubMed PMID: 30715605
Smith TL, Beswick DM, Kennedy DW, Ramakrishnan VR, Soler ZM. Deadly amoeba infections from nasal and sinus irrigation: how should we discuss with our patients?. Int Forum Allergy Rhinol. 2019 Apr;9(4):435-437. PubMed PMID: 30657647
Ramakrishnan VR, Mace JC, Soler ZM, Smith TL. Is greater antibiotic therapy prior to ESS associated with differences in surgical outcomes in CRS?. Laryngoscope. 2019 Mar;129(3):558-566. PubMed PMID: 30582166
Farrell NF, Kingdom TT, Getz AE, Lillehei KO, Youssef AS, Ramakrishnan VR. Development of Chronic Sphenoid Sinusitis After Sellar Reconstruction with Medpor Porous Polyethylene Implant. World Neurosurg. 2019 Mar;123:e781-e786. PubMed PMID: 30579017
Lee JT, Kim CM, Ramakrishnan V. Microbiome and disease in the upper airway. Curr Opin Allergy Clin Immunol. 2019 Feb;19(1):1-6. PubMed PMID: 30543547
Ramakrishnan VR. Ergonomics in endoscopic sinus surgery. Curr Opin Otolaryngol Head Neck Surg. 2019 Feb;27(1):25-28. PubMed PMID: 30516549
Alt JA, Ramakrishnan VR, Platt MP, Schlosser RJ, Storck T, Soler ZM. Impact of chronic rhinosinusitis on sleep: a controlled clinical study. Int Forum Allergy Rhinol. 2019 Jan;9(1):16-22. PubMed PMID: 30281930
Baschal EE, Larson ED, Bootpetch Roberts TC, Pathak S, Frank G, Handley E, Dinwiddie J, Moloney M, Yoon PJ, Gubbels SP, Scholes MA, Cass SP, Jenkins HA, Frank DN, Yang IV, Schwartz DA, Ramakrishnan VR, Santos-Cortez RLP. Identification of Novel Genes and Biological Pathways That Overlap in Infectious and Nonallergic Diseases of the Upper and Lower Airways Using Network Analyses. Front Genet. 2019;10:1352. PubMed PMID: 32010199
Baschal EE, Larson ED, Bootpetch Roberts TC, Pathak S, Frank G, Handley E, Dinwiddie J, Moloney M, Yoon PJ, Gubbels SP, Scholes MA, Cass SP, Jenkins HA, Frank DN, Yang IV, Schwartz DA, Ramakrishnan VR, Santos-Cortez RLP. Identification of Novel Genes and Biological Pathways That Overlap in Infectious and Nonallergic Diseases of the Upper and Lower Airways Using Network Analyses. Front Genet. 2019;10:1352. PubMed PMID: 32010199
Ramakrishnan VR. Ergonomics in endoscopic sinus surgery. Curr Opin Otolaryngol Head Neck Surg. 2018 Dec 3. [Epub ahead of print] PubMed PMID: 30516549
Alt JA, Ramakrishnan VR, Platt MP, Schlosser RJ, Storck T, Soler ZM. Impact of chronic rhinosinusitis on sleep: a controlled clinical study. Int Forum Allergy Rhinol. 2018 Oct 3. [Epub ahead of print] PubMed PMID: 30281930
Aref M, Kunigelis KE, Yang A, Subramanian PS, Ramakrishnan VR, Youssef AS. The Effect of Preoperative Direct Ligation of Ethmoidal Arteries on the Perioperative Outcomes of Large Anterior Skull Base Meningiomas Surgery: A Clinical Study. World Neurosurg. 2018 Dec;120:e776-e782. PubMed PMID: 30196172
Aref M, Kunigelis KE, Yang A, Subramanian PS, Ramakrishnan VR, Youssef AS. The Effect of Preoperative Direct Ligation of Ethmoidal Arteries on the Perioperative Outcomes of Large Anterior Skull Base Meningiomas Surgery: A Clinical Study. World Neurosurg. 2018 Dec;120:e776-e782. PubMed PMID: 30196172
Ramakrishnan VR, Holt J, Nelson LF, Ir D, Robertson CE, Frank DN. Determinants of the Nasal Microbiome: Pilot Study of Effects of Intranasal Medication Use. Allergy Rhinol (Providence). 2018 Jan-Dec;9:2152656718789519. PubMed PMID: 30128169
Ramakrishnan VR, Holt J, Nelson LF, Ir D, Robertson CE, Frank DN. Determinants of the Nasal Microbiome: Pilot Study of Effects of Intranasal Medication Use. Allergy Rhinol (Providence). 2018 Jan-Dec;9:2152656718789519. PubMed PMID: 30128169
Ramakrishnan VR, Frank DN. Microbiome in patients with upper airway disease: Moving from taxonomic findings to mechanisms and causality. J Allergy Clin Immunol. 2018 Jul;142(1):73-75. PubMed PMID: 29803801
Hararah MK, Mattingly JK, Ramakrishnan VR. Use of a Contralateral Nasoseptal Flap for Sino-Orbital Fistula Closure. J Craniofac Surg. 2018 May;29(3):709-711. PubMed PMID: 29723950
Freeman JL, Sampath R, Quattlebaum SC, Casey MA, Folzenlogen ZA, Ramakrishnan VR, Youssef AS. Expanding the endoscopic transpterygoid corridor to the petroclival region: anatomical study and volumetric comparative analysis. J Neurosurg. 2018 Jun;128(6):1855-1864. PubMed PMID: 28731399
DeConde AS, Mace JC, Ramakrishnan VR, Alt JA, Smith TL. Analysis of factors associated with electing endoscopic sinus surgery. Laryngoscope. 2018 Feb;128(2):304-310. PubMed PMID: 28776718
Levy JM, Smith SS, Varshney R, Chang EH, Ramakrishnan VR, Ting JY, Bleier BS. Trends in sinusitis research: a systematic review of extramural funding. Int Forum Allergy Rhinol. 2017 Nov;7(11):1104-1107. PubMed PMID: 28985031
Sokoya M, Ramakrishnan VR, Frank DN, Rahkola J, Getz A, Kingdom TT, Kofonow JM, Nguyen Q, Janoff EN. Expression of immunoglobulin D is increased in chronic rhinosinusitis. Ann Allergy Asthma Immunol. 2017 Oct;119(4):317-323.e1. PubMed PMID: 28958373
Ramakrishnan VR, Gonzalez JR, Cooper SE, Barham HP, Anderson CB, Larson ED, Cool CD, Diller JD, Jones K, Kinnamon SC. RNA sequencing and pathway analysis identify tumor necrosis factor alpha driven small proline-rich protein dysregulation in chronic rhinosinusitis. Am J Rhinol Allergy. 2017 Sep 1;31(5):283-288. PubMed PMID: 28859701
DeConde AS, Mace JC, Ramakrishnan VR, Alt JA, Smith TL. Analysis of factors associated with electing endoscopic sinus surgery. Laryngoscope. 2017 Aug 4. [Epub ahead of print] PubMed PMID: 28776718
Freeman JL, Sampath R, Quattlebaum SC, Casey MA, Folzenlogen ZA, Ramakrishnan VR, Youssef AS. Expanding the endoscopic transpterygoid corridor to the petroclival region: anatomical study and volumetric comparative analysis. J Neurosurg. 2017 Jul 21;:1-10. [Epub ahead of print] PubMed PMID: 28731399
Alt JA, Ramakrishnan VR, Platt MP, Kohli P, Storck KA, Schlosser RJ, Soler ZM. Response to: Can patients with chronic rhinosinusitis recover normal sleep after endoscopic sinus surgery?. Int Forum Allergy Rhinol. 2017 Sep;7(9):927. PubMed PMID: 28703438
Ramakrishnan VR. A call for critical examination of endoscopically guided cultures in chronic rhinosinusitis. Int Forum Allergy Rhinol. 2017 Aug;7(8):842-843. PubMed PMID: 28658539
Vickery TW, Kofonow JM, Ramakrishnan VR. Characterization of Sinus Microbiota by 16S Sequencing from Swabs. Methods Mol Biol. 2017;1616:23-38. PubMed PMID: 28600760
Maxwell AK, Barham HP, Getz AE, Kingdom TT, Ramakrishnan VR. Landmarks for rapid localization of the sphenopalatine foramen: A radiographic morphometric analysis. Allergy Rhinol (Providence). 2017 Jun 1;8(2):63-66. PubMed PMID: 28583229
Ramakrishnan VR, Milam BM. Ergonomic analysis of the surgical position in functional endoscopic sinus surgery. Int Forum Allergy Rhinol. 2017 Jun;7(6):570-575. PubMed PMID: 28296272
Edward JA, Sanyal M, Le W, Soudry E, Ramakrishnan VR, Bravo DT, Nguyen AL, Zarabanda D, Kingdom TT, Hwang PH, Garrison Fathman C, Nayak JV. Selective expansion of human regulatory T cells in nasal polyps, and not adjacent tissue microenvironments, in individual patients exposed to steroids. Clin Immunol. 2017 Jun;179:66-76. PubMed PMID: 28279811
Ramakrishnan VR, Mace JC, Soler ZM, Smith TL. Examination of high-antibiotic users in a multi-institutional cohort of chronic rhinosinusitis patients. Int Forum Allergy Rhinol. 2017 Apr;7(4):343-351. PubMed PMID: 28084683
Vickery TW, Ramakrishnan VR. Bacterial Pathogens and the Microbiome. Otolaryngol Clin North Am. 2017 Feb;50(1):29-47. PubMed PMID: 27888914
Ramakrishnan VR, Terella AM, Poonia S, Chiu AG, Palmer JN. Osseous Repair in Minimally Invasive Reconstruction of Anterior Skull Base Defects. J Craniofac Surg. 2017 Jan;28(1):36-39. PubMed PMID: 27875509
Alt JA, Ramakrishnan VR, Platt MP, Kohli P, Storck KA, Schlosser RJ, Soler ZM. Sleep quality outcomes after medical and surgical management of chronic rhinosinusitis. Int Forum Allergy Rhinol. 2017 Feb;7(2):113-118. PubMed PMID: 27673437
Ramakrishnan VR, Gitomer S, Kofonow JM, Robertson CE, Frank DN. Investigation of sinonasal microbiome spatial organization in chronic rhinosinusitis. Int Forum Allergy Rhinol. 2017 Jan;7(1):16-23. PubMed PMID: 27627048
Jetté M, Anderson C, Ramakrishnan V. Case Report: Diagnosis of hypogeusia after oral exposure to commercial cleaning agent and considerations for clinical taste testing. F1000Res. 2017;6:373. PubMed PMID: 28713552
Hummel T, Whitcroft KL, Andrews P, Altundag A, Cinghi C, Costanzo RM, Damm M, Frasnelli J, Gudziol H, Gupta N, Haehner A, Holbrook E, Hong SC, Hornung D, Hüttenbrink KB, Kamel R, Kobayashi M, Konstantinidis I, Landis BN, Leopold DA, Macchi A, Miwa T, Moesges R, Mullol J, Mueller CA, Ottaviano G, Passali GC, Philpott C, Pinto JM, Ramakrishnan VJ, Rombaux P, Roth Y, Schlosser RA, Shu B, Soler G, Stjärne P, Stuck BA, Vodicka J, Welge-Luessen A. Position paper on olfactory dysfunction. Rhinology. 2017 Jun 17. [Epub ahead of print] PubMed PMID: 28623665
Hummel T, Whitcroft KL, Andrews P, Altundag A, Cinghi C, Costanzo RM, Damm M, Frasnelli J, Gudziol H, Gupta N, Haehne A, Holbrook E, Hong SC, Hornung D, Hüttenbrink KB, Kamel R, Kobayashi M, Konstantinidis I, Landis BN, Leopold DA, Macchi A, Miwa T, Moesges R, Mullol J, Mueller CA, Ottaviano G, Passali GC, Philpott C, Pinto JM, Ramakrishnan VJ, Rombaux P, Roth Y, Schlosser RA, Shu B, Soler G, Stjärne P, Stuck BA, Vodicka J, Welge-Luessen A. Position paper on olfactory dysfunction. Rhinol Suppl. 2017 Mar;54(26):1-30. PubMed PMID: 29528615
Sokoya M, Ramakrishnan VR, Frank DN, Rahkola J, Getz A, Kingdom TT, Kofonow JM, Nguyen Q, Janoff EN. Expression of immunoglobulin D is increased in chronic rhinosinusitis. Ann Allergy Asthma Immunol. 2017 Oct;119(4):317-323.e1. PubMed PMID: 28958373
Sokoya M, Ramakrishnan VR, Frank DN, Rahkola J, Getz A, Kingdom TT, Kofonow JM, Nguyen Q, Janoff EN. Expression of immunoglobulin D is increased in chronic rhinosinusitis. Ann Allergy Asthma Immunol. 2017 Oct;119(4):317-323.e1. PubMed PMID: 28958373
Levy JM, Smith SS, Varshney R, Chang EH, Ramakrishnan VR, Ting JY, Bleier BS. Trends in sinusitis research: a systematic review of extramural funding. Int Forum Allergy Rhinol. 2017 Nov;7(11):1104-1107. PubMed PMID: 28985031
Ramakrishnan VR, Gonzalez JR, Cooper SE, Barham HP, Anderson CB, Larson ED, Cool CD, Diller JD, Jones K, Kinnamon SC. RNA sequencing and pathway analysis identify tumor necrosis factor alpha driven small proline-rich protein dysregulation in chronic rhinosinusitis. Am J Rhinol Allergy. 2017 Sep 1;31(5):283-288. PubMed PMID: 28859701
Jetté M, Anderson C, Ramakrishnan V. Case Report: Diagnosis of hypogeusia after oral exposure to commercial cleaning agent and considerations for clinical taste testing. F1000Res. 2017;6:373. PubMed PMID: 28713552
Alt JA, Ramakrishnan VR, Platt MP, Kohli P, Storck KA, Schlosser RJ, Soler ZM. Response to: Can patients with chronic rhinosinusitis recover normal sleep after endoscopic sinus surgery?. Int Forum Allergy Rhinol. 2017 Sep;7(9):927. PubMed PMID: 28703438
Ramakrishnan VR. A call for critical examination of endoscopically guided cultures in chronic rhinosinusitis. Int Forum Allergy Rhinol. 2017 Aug;7(8):842-843. PubMed PMID: 28658539
Vickery TW, Kofonow JM, Ramakrishnan VR. Characterization of Sinus Microbiota by 16S Sequencing from Swabs. Methods Mol Biol. 2017;1616:23-38. PubMed PMID: 28600760
Maxwell AK, Barham HP, Getz AE, Kingdom TT, Ramakrishnan VR. Landmarks for rapid localization of the sphenopalatine foramen: A radiographic morphometric analysis. Allergy Rhinol (Providence). 2017 Jun 1;8(2):63-66. PubMed PMID: 28583229
Maxwell AK, Barham HP, Getz AE, Kingdom TT, Ramakrishnan VR. Landmarks for rapid localization of the sphenopalatine foramen: A radiographic morphometric analysis. Allergy Rhinol (Providence). 2017 Jun 1;8(2):63-66. PubMed PMID: 28583229
Ramakrishnan VR, Milam BM. Ergonomic analysis of the surgical position in functional endoscopic sinus surgery. Int Forum Allergy Rhinol. 2017 Jun;7(6):570-575. PubMed PMID: 28296272
Edward JA, Sanyal M, Le W, Soudry E, Ramakrishnan VR, Bravo DT, Nguyen AL, Zarabanda D, Kingdom TT, Hwang PH, Garrison Fathman C, Nayak JV. Selective expansion of human regulatory T cells in nasal polyps, and not adjacent tissue microenvironments, in individual patients exposed to steroids. Clin Immunol. 2017 Jun;179:66-76. PubMed PMID: 28279811
Ramakrishnan VR, Mace JC, Soler ZM, Smith TL. Examination of high-antibiotic users in a multi-institutional cohort of chronic rhinosinusitis patients. Int Forum Allergy Rhinol. 2017 Apr;7(4):343-351. PubMed PMID: 28084683
Vickery TW, Ramakrishnan VR. Bacterial Pathogens and the Microbiome. Otolaryngol Clin North Am. 2017 Feb;50(1):29-47. PubMed PMID: 27888914
Vickery TW, Ramakrishnan VR. Bacterial Pathogens and the Microbiome. Otolaryngol Clin North Am. 2017 Feb;50(1):29-47. PubMed PMID: 27888914
Ramakrishnan VR, Terella AM, Poonia S, Chiu AG, Palmer JN. Osseous Repair in Minimally Invasive Reconstruction of Anterior Skull Base Defects. J Craniofac Surg. 2017 Jan;28(1):36-39. PubMed PMID: 27875509
Alt JA, Ramakrishnan VR, Platt MP, Kohli P, Storck KA, Schlosser RJ, Soler ZM. Sleep quality outcomes after medical and surgical management of chronic rhinosinusitis. Int Forum Allergy Rhinol. 2017 Feb;7(2):113-118. PubMed PMID: 27673437
Ramakrishnan VR, Gitomer S, Kofonow JM, Robertson CE, Frank DN. Investigation of sinonasal microbiome spatial organization in chronic rhinosinusitis. Int Forum Allergy Rhinol. 2017 Jan;7(1):16-23. PubMed PMID: 27627048
Mattingly JK, Ramakrishnan VR. Rhinocerebral Mucormycosis of the Optic Nerve. Otolaryngol Head Neck Surg. 2016 Nov;155(5):888-889. PubMed PMID: 27352893
Alt JA, Ramakrishnan VR, Platt MP, Kohli P, Storck KA, Schlosser RJ, Soler ZM. Sleep quality outcomes after medical and surgical management of chronic rhinosinusitis. Int Forum Allergy Rhinol. 2016 Sep 27. [Epub ahead of print] PubMed PMID: 27673437
Ramakrishnan VR, Gitomer S, Kofonow JM, Robertson CE, Frank DN. Investigation of sinonasal microbiome spatial organization in chronic rhinosinusitis. Int Forum Allergy Rhinol. 2016 Sep 14. [Epub ahead of print] PubMed PMID: 27627048
Youssef AS, Sampath R, Freeman JL, Mattingly JK, Ramakrishnan VR. Unilateral endonasal transcribriform approach with septal transposition for olfactory groove meningioma: can olfaction be preserved?. Acta Neurochir (Wien). 2016 Oct;158(10):1965-72. PubMed PMID: 27562683
Freeman JL, Sampath R, Casey MA, Quattlebaum SC, Ramakrishnan VR, Youssef AS. Transposition of the paraclival carotid artery: a novel concept of self-retaining vascular retraction during endoscopic endonasal skull base surgery technical report. Acta Neurochir (Wien). 2016 Aug;158(8):1625-9. PubMed PMID: 27339269
Suh JD, Kuan EC, Thompson CF, Scawn RL, Feinstein AJ, Barham HP, Kingdom TT, Ramakrishnan VR. Using fixed anatomical landmarks to avoid medial rectus injury: a radiographic analysis in patients with and without Graves' disease. Am J Otolaryngol. 2016 Jul-Aug;37(4):334-8. PubMed PMID: 27040416
Hauser LJ, Ir D, Kingdom TT, Robertson CE, Frank DN, Ramakrishnan VR. Evaluation of bacterial transmission to the paranasal sinuses through sinus irrigation. Int Forum Allergy Rhinol. 2016 Aug;6(8):800-6. PubMed PMID: 26990369
Gitomer SA, Fountain CR, Kingdom TT, Getz AE, Sillau SH, Katial RK, Ramakrishnan VR. Clinical Examination of Tissue Eosinophilia in Patients with Chronic Rhinosinusitis and Nasal Polyposis. Otolaryngol Head Neck Surg. 2016 Jul;155(1):173-8. PubMed PMID: 26980909
Rosen SA, Getz AE, Kingdom T, Youssef AS, Ramakrishnan VR. Systematic review of the effectiveness of perioperative prophylactic antibiotics for skull base surgeries. Am J Rhinol Allergy. 2016 Mar-Apr;30(2):e10-6. PubMed PMID: 26980379
Orlandi RR, Kingdom TT, Hwang PH, Smith TL, Alt JA, Baroody FM, Batra PS, Bernal-Sprekelsen M, Bhattacharyya N, Chandra RK, Chiu A, Citardi MJ, Cohen NA, DelGaudio J, Desrosiers M, Dhong HJ, Douglas R, Ferguson B, Fokkens WJ, Georgalas C, Goldberg A, Gosepath J, Hamilos DL, Han JK, Harvey R, Hellings P, Hopkins C, Jankowski R, Javer AR, Kern R, Kountakis S, Kowalski ML, Lane A, Lanza DC, Lebowitz R, Lee HM, Lin SY, Lund V, Luong A, Mann W, Marple BF, McMains KC, Metson R, Naclerio R, Nayak JV, Otori N, Palmer JN, Parikh SR, Passali D, Peters A, Piccirillo J, Poetker DM, Psaltis AJ, Ramadan HH, Ramakrishnan VR, Riechelmann H, Roh HJ, Rudmik L, Sacks R, Schlosser RJ, Senior BA, Sindwani R, Stankiewicz JA, Stewart M, Tan BK, Toskala E, Voegels R, Wang de Y, Weitzel EK, Wise S, Woodworth BA, Wormald PJ, Wright ED, Zhou B, Kennedy DW. International Consensus Statement on Allergy and Rhinology: Rhinosinusitis. Int Forum Allergy Rhinol. 2016 Feb;6 Suppl 1:S22-209. PubMed PMID: 26889651
Barham HP, Ramakrishnan VR, Knisely A, Do TQ, Chan LS, Gunaratne DA, Weston JD, Seneviratne S, Marcells GN, Sacks R, Harvey RJ. Frontal sinus surgery and sinus distribution of nasal irrigation. Int Forum Allergy Rhinol. 2016 Mar;6(3):238-42. PubMed PMID: 26750306
Soler ZM, Smith TL, Alt JA, Ramakrishnan VR, Mace JC, Schlosser RJ. Olfactory-specific quality of life outcomes after endoscopic sinus surgery. Int Forum Allergy Rhinol. 2016 Apr;6(4):407-13. PubMed PMID: 26678351
Bleier BS, Castelnuovo P, Battaglia P, Turri-Zanoni M, Dallan I, Metson R, Sedaghat AR, Stefko ST, Gardner PA, Snyderman CH, Nogueira JF, Ramakrishnan VR, Muscatello L, Lenzi R, Freitag S. Endoscopic endonasal orbital cavernous hemangioma resection: global experience in techniques and outcomes. Int Forum Allergy Rhinol. 2016 Feb;6(2):156-61. PubMed PMID: 26623968
Ramakrishnan VR, Hauser LJ, Frank DN. The sinonasal bacterial microbiome in health and disease. Curr Opin Otolaryngol Head Neck Surg. 2016 Feb;24(1):20-5. PubMed PMID: 26575518
Hauser LJ, Ir D, Kingdom TT, Robertson CE, Frank DN, Ramakrishnan VR. Investigation of bacterial repopulation after sinus surgery and perioperative antibiotics. Int Forum Allergy Rhinol. 2016 Jan;6(1):34-40. PubMed PMID: 26388320
Ung TH, Waziri AE, Ramakrishnan VR. Preoperative ethmoid artery ligation facilitates resection of large sub-frontal meningiomas. Am J Otolaryngol. 2014 Jan 10. [Epub ahead of print] PubMed PMID: 24499924
Beckmann N, Ponnappan A, Campana J, Ramakrishnan VR. Posterior septal resection: a simple surgical option for management of nasal septal perforation. JAMA Otolaryngol Head Neck Surg. 2014 Feb 1;140(2):150-4. PubMed PMID: 24337531
Ramakrishnan VR, Feazel LM, Gitomer SA, Ir D, Robertson CE, Frank DN. The microbiome of the middle meatus in healthy adults. PLoS One. 2013;8(12):e85507. PubMed PMID: 24386477
Fountain CR, Mudd PA, Ramakrishnan VR, Sillau SH, Kingdom TT, Katial RK. Characterization and treatment of patients with chronic rhinosinusitis and nasal polyps. Ann Allergy Asthma Immunol. 2013 Nov;111(5):337-41. PubMed PMID: 24125137
Miller C, Suh JD, Henriquez OA, Schlosser RJ, Ramakrishnan VR, Chiu AG. Prognosis for sixth nerve palsy arising from paranasal sinus disease. Am J Rhinol Allergy. 2013 Sep-Oct;27(5):432-5. PubMed PMID: 24119609
Edward JA, Sanyal M, Ramakrishnan VR, Le W, Nguyen AL, Kingdom TT, Hwang PH, Nayak JV. Systemic prednisone administration selectively alters granulocyte subsets in nasal polyps from aspirin-exacerbated respiratory disease and chronic rhinosinusitis patients. Int Forum Allergy Rhinol. 2013 Nov;3(11):866-76. PubMed PMID: 24106221
Ramakrishnan VR, Ferril GR, Suh JD, Woodson T, Green TJ, Kingdom TT. Upper and lower airways associations in patients with chronic rhinosinusitis and bronchiectasis. Int Forum Allergy Rhinol. 2013 Nov;3(11):921-7. PubMed PMID: 23881553
Ramakrishnan VR, Lee JY, O'Malley BW Jr, Palmer JN, Chiu AG. 18-FDG-PET in the initial staging of sinonasal malignancy. Laryngoscope. 2013 Dec;123(12):2962-6. PubMed PMID: 23877974
Barham HP, Said S, Ramakrishnan VR. Colliding tumor of the paranasal sinus. Allergy Rhinol (Providence). 2013 Spring;4(1):e13-6. PubMed PMID: 23772319
Harasaki Y, Pettijohn KJ, Waziri A, Ramakrishnan VR. Frontoethmoid osteoma with pneumocephalus: options for surgical management. J Craniofac Surg. 2013 May;24(3):953-6. PubMed PMID: 23714919
Ramakrishnan VR, Montero PN. Ergonomic considerations in endoscopic sinus surgery: lessons learned from laparoscopic surgeons. Am J Rhinol Allergy. 2013 May-Jun;27(3):245-50. PubMed PMID: 23710962
Ramakrishnan VR, Suh JD, Lee JY, O'Malley BW Jr, Grady MS, Palmer JN. Sphenoid sinus anatomy and suprasellar extension of pituitary tumors. J Neurosurg. 2013 Sep;119(3):669-74. PubMed PMID: 23621599
Suh JD, Ramakrishnan VR, Chi JJ, Palmer JN, Chiu AG. Outcomes and complications of endoscopic approaches for malignancies of the paranasal sinuses and anterior skull base. Ann Otol Rhinol Laryngol. 2013 Jan;122(1):54-9. PubMed PMID: 23472317
Barham HP, Cooper SE, Anderson CB, Tizzano M, Kingdom TT, Finger TE, Kinnamon SC, Ramakrishnan VR. Solitary chemosensory cells and bitter taste receptor signaling in human sinonasal mucosa. Int Forum Allergy Rhinol. 2013 Jun;3(6):450-7. PubMed PMID: 23404938
Ramakrishnan JB, Kingdom TT, Ramakrishnan VR. Allergic rhinitis and chronic rhinosinusitis: their impact on lower airways. Immunol Allergy Clin North Am. 2013 Feb;33(1):45-60. PubMed PMID: 23337064
Ramakrishnan VR, Waziri A. Postoperative care following skull base reconstruction. Adv Otorhinolaryngol. 2013;74:138-47. PubMed PMID: 23257560
Scapa VI, Ramakrishnan VR, Kingdom TT. Upregulation of Bcl-2 in nasal polyps from patients with cystic fibrosis. Int Forum Allergy Rhinol. 2013 Mar;3(3):199-203. PubMed PMID: 23135964
Ramakrishnan VR, Feazel LM, Abrass LJ, Frank DN. Prevalence and abundance of Staphylococcus aureus in the middle meatus of patients with chronic rhinosinusitis, nasal polyps, and asthma. Int Forum Allergy Rhinol. 2013 Apr;3(4):267-71. PubMed PMID: 23055295
Ramakrishnan VR, Orlandi RR, Citardi MJ, Smith TL, Fried MP, Kingdom TT. The use of image-guided surgery in endoscopic sinus surgery: an evidence-based review with recommendations. Int Forum Allergy Rhinol. 2013 Mar;3(3):236-41. PubMed PMID: 23044799
Clinical Interests
I am interested in Endoscopic Sinus Surgery and I have subspecialty training in this area
Read about one patient's experience with Dr. Ramakrishnan and the innovative endoscopic or endo-nasal orbital surgery Dr. Ramakrishnan performed in this Channel 7 News Article.
General Information
Medical Schools:
MD, Baylor College of Medicine
(2004)
Undergraduate Schools:
BA, University of Texas–Austin (TX)
(2000)
Internships:
University of Colorado (University Hospital) Program
(2005)
Residency Programs:
University of Colorado, Chief Resident, Otolaryngology (2009)