Carl White, MD
Clinical Professor, Pediatrics-Pulmonary Medicine

Photo
Medical School:
  • MD, Baylor College of Medicine (1978)
Undergraduate School:
  • BA, Earlham College (IN) (1974)
Internship:
  • Baylor College of Medicine Program (1979)
Residency:
  • Baylor College of Medicine Program, Chief Resident, Pediatrics (1981)
Fellowships:
  • University of Colorado, Pediatric Pulmonology (1984)
Languages: English, Spanish
Department: Pediatrics-Pulmonary Medicine

Research Interests

My research focuses on Cellular and Molecular Biology and Other Pulmonary Disease Research.

Teaching

  • Professor (1985)
    School of Medicine, Pediatrics
    Oxidative stress, antioxidants; toxic inhaled chemicals; coagulation system and its actions in the lung and airways

Publications

  • Nick HJ, Johnson CA, Stewart AR, Christeson SE, Bloomquist LA, Appel AS, Donkor AB, Veress LA, Logue BA, Bratcher PE, White CW. Mesna Improves Outcomes of Sulfur Mustard Inhalation Toxicity in an Acute Rat Model. J Pharmacol Exp Ther. 2023 Aug 4. [Epub ahead of print] PubMed PMID: 37541763
  • Hinds DM, Nick HJ, Vallin TM, Bloomquist LA, Christeson S, Bratcher PE, Cooper EH, Brinton JT, Bosco-Lauth A, White CW. Acute vaping in a golden Syrian hamster causes inflammatory response transcriptomic changes. Am J Physiol Lung Cell Mol Physiol. 2022 Nov 1;323(5):L525-L535. PubMed PMID: 36041220
  • Donkor AB, White CW, Nick HJ, Logue BA. Analysis of sodium 2-mercaptoethane sulfonate in rat plasma using high performance liquid chromatography tandem-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2022 Jan 15;1189:123088. PubMed PMID: 34974317
  • Donkor AB, Gyamfi OA, White CW, Nick HJ, Rioux JS, Veress LA, Logue BA. Identification and determination of phenyl methyl carbamate released from adducted hemoglobin for methyl isocyanate exposure verification. J Chromatogr A. 2022 Oct 11;1681:463454. PubMed PMID: 36099696
  • Raghavan S, Kundumani-Sridharan V, Kumar S, White CW, Das KC. Thioredoxin Prevents Loss of UCP2 in Hyperoxia via MKK4-p38 MAPK-PGC1a Signaling and Limits Oxygen Toxicity. Am J Respir Cell Mol Biol. 2022 Mar;66(3):323-336. PubMed PMID: 34890296
  • Philipopoulos GP, Tat J, Chan A, Jiang J, Mukai D, Burney T, Doosty M, Mahon S, Patel HH, White CW, Brenner M, Lee J, Boss GR. Methyl mercaptan gas: mechanisms of toxicity and demonstration of the effectiveness of cobinamide as an antidote in mice and rabbits. Clin Toxicol (Phila). 2022 May;60(5):615-622. PubMed PMID: 34989638
  • Hinds DM, Nick HJ, Vallin TM, Bloomquist LA, Christeson S, Bratcher PE, Cooper EH, Brinton JT, Bosco-Lauth A, White CW. Acute vaping in a golden Syrian hamster causes inflammatory response transcriptomic changes. Am J Physiol Lung Cell Mol Physiol. 2022 Nov 1;323(5):L525-L535. PubMed PMID: 36041220
  • Raghavan S, Kundumani-Sridharan V, Kumar S, White CW, Das KC. Thioredoxin Prevents Loss of UCP2 in Hyperoxia via MKK4-p38 MAPK-PGC1a Signaling and Limits Oxygen Toxicity. Am J Respir Cell Mol Biol. 2022 Mar;66(3):323-336. PubMed PMID: 34890296
  • Donkor AB, White CW, Nick HJ, Logue BA. Analysis of sodium 2-mercaptoethane sulfonate in rat plasma using high performance liquid chromatography tandem-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2022 Jan 15;1189:123088. PubMed PMID: 34974317
  • Donkor AB, Gyamfi OA, White CW, Nick HJ, Rioux JS, Veress LA, Logue BA. Identification and determination of phenyl methyl carbamate released from adducted hemoglobin for methyl isocyanate exposure verification. J Chromatogr A. 2022 Oct 11;1681:463454. PubMed PMID: 36099696
  • Philipopoulos GP, Tat J, Chan A, Jiang J, Mukai D, Burney T, Doosty M, Mahon S, Patel HH, White CW, Brenner M, Lee J, Boss GR. Methyl mercaptan gas: mechanisms of toxicity and demonstration of the effectiveness of cobinamide as an antidote in mice and rabbits. Clin Toxicol (Phila). 2022 May;60(5):615-622. PubMed PMID: 34989638
  • Hendry-Hofer TB, Ng PC, McGrath AM, Soules K, Mukai DS, Chan A, Maddry JK, White CW, Lee J, Mahon SB, Brenner M, Boss GR, Bebarta VS. Intramuscular cobinamide as an antidote to methyl mercaptan poisoning. Inhal Toxicol. 2021 Jan;33(1):25-32. PubMed PMID: 33356664
  • Somasundaram Raghavan, Venkatesh Kundumani-Sridharan, Sudhir Kumar, Carl W. White, and Kumuda C. Das. Thioredoxin-prevents loss of UCP2 in hyperoxia via MKK4-p38 MAPK- PGC1a signaling and limits oxygen toxicity. In press, Am J Lung Cell Molec Biol, 2021 (the Red Journal)
  • Hendry-Hofer TB, Ng PC, McGrath AM, Soules K, Mukai DS, Chan A, Maddry JK, White CW, Lee J, Mahon SB, Brenner M, Boss GR, Bebarta VS. Intramuscular cobinamide as an antidote to methyl mercaptan poisoning. Inhal Toxicol. 2021 Jan;33(1):25-32. PubMed PMID: 33356664
  • Thurston GD, Balmes JR, Garcia E, Gilliland FD, Rice MB, Schikowski T, Van Winkle LS, Annesi-Maesano I, Burchard EG, Carlsten C, Harkema JR, Khreis H, Kleeberger SR, Kodavanti UP, London SJ, McConnell R, Peden DB, Pinkerton KE, Reibman J, White CW. Outdoor Air Pollution and New-Onset Airway Disease. An Official American Thoracic Society Workshop Report. Ann Am Thorac Soc. 2020 Apr;17(4):387-398. PubMed PMID: 32233861
  • Gyamfi OA, Bortey-Sam N, Donkor AB, White CW, Logue BA. Analysis of TRPA1 antagonist, A-967079, in plasma using high-performance liquid chromatography tandem mass-spectrometry. J Pharm Anal. 2020 Apr;10(2):157-163. PubMed PMID: 32373387
  • Hirsch K, Taglauer E, Seedorf G, Callahan C, Mandell E, White CW, Kourembanas S, Abman SH. Perinatal Hypoxia-Inducible Factor Stabilization Preserves Lung Alveolar and Vascular Growth in Experimental Bronchopulmonary Dysplasia. Am J Respir Crit Care Med. 2020 Oct 15;202(8):1146-1158. PubMed PMID: 32551816
  • McGraw MD, Kim SY, White CW, Veress LA. Acute cytotoxicity and increased vascular endothelial growth factor after in vitro nitrogen mustard vapor exposure. Ann N Y Acad Sci. 2020 Nov;1479(1):223-233. PubMed PMID: 32408394
  • Nick HJ, Rioux JS, Veress LA, Bratcher PE, Bloomquist LA, Anantharam P, Croutch CR, Tuttle RS, Peters E, Sosna W, White CW. Alleviation of methyl isocyanate-induced airway obstruction and mortality by tissue plasminogen activator. Ann N Y Acad Sci. 2020 Nov;1479(1):134-147. PubMed PMID: 32233099
  • McGraw MD, Kim SY, White CW, Veress LA. Acute cytotoxicity and increased vascular endothelial growth factor after in vitro nitrogen mustard vapor exposure. Ann N Y Acad Sci. 2020 Nov;1479(1):223-233. PubMed PMID: 32408394
  • Gyamfi OA, Bortey-Sam N, Donkor AB, White CW, Logue BA. Analysis of TRPA1 antagonist, A-967079, in plasma using high-performance liquid chromatography tandem mass-spectrometry. J Pharm Anal. 2020 Apr;10(2):157-163. PubMed PMID: 32373387
  • Thurston GD, Balmes JR, Garcia E, Gilliland FD, Rice MB, Schikowski T, Van Winkle LS, Annesi-Maesano I, Burchard EG, Carlsten C, Harkema JR, Khreis H, Kleeberger SR, Kodavanti UP, London SJ, McConnell R, Peden DB, Pinkerton KE, Reibman J, White CW. Outdoor Air Pollution and New-Onset Airway Disease. An Official American Thoracic Society Workshop Report. Ann Am Thorac Soc. 2020 Apr;17(4):387-398. PubMed PMID: 32233861
  • Nick HJ, Rioux JS, Veress LA, Bratcher PE, Bloomquist LA, Anantharam P, Croutch CR, Tuttle RS, Peters E, Sosna W, White CW. Alleviation of methyl isocyanate-induced airway obstruction and mortality by tissue plasminogen activator. Ann N Y Acad Sci. 2020 Nov;1479(1):134-147. PubMed PMID: 32233099
  • Hirsch K, Taglauer E, Seedorf G, Callahan C, Mandell E, White CW, Kourembanas S, Abman SH. Perinatal Hypoxia-Inducible Factor Stabilization Preserves Lung Alveolar and Vascular Growth in Experimental Bronchopulmonary Dysplasia. Am J Respir Crit Care Med. 2020 Oct 15;202(8):1146-1158. PubMed PMID: 32551816
  • Rancourt RC, Rioux JS, Veress LA, Garlick RB, Croutch CR, Peters E, Sosna W, White CW. Methyl isocyanate inhalation induces tissue factor-dependent activation of coagulation in rats. Drug Chem Toxicol. 2019 May;42(3):321-327. PubMed PMID: 30426789
  • Rancourt RC, Rioux JS, Veress LA, Garlick RB, Croutch CR, Peters E, Sosna W, White CW. Methyl isocyanate inhalation induces tissue factor-dependent activation of coagulation in rats. Drug Chem Toxicol. 2018 Nov 14;:1-7. [Epub ahead of print] PubMed PMID: 30426789
  • Logue BA, Zhang Z, Manandhar E, Pay AL, Croutch CR, Peters E, Sosna W, Rioux JS, Veress LA, White CW. Determination of methyl isopropyl hydantoin from rat erythrocytes by gas-chromatography mass-spectrometry to determine methyl isocyanate dose following inhalation exposure. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Sep 1;1093-1094:119-127. PubMed PMID: 30015309
  • Miao Y, Jing JC, Desai V, Mahon SB, Brenner M, Veress LA, White CW, Chen Z. Automated 3D segmentation of methyl isocyanate-exposed rat trachea using an ultra-thin, fully fiber optic optical coherence endoscopic probe. Sci Rep. 2018 Jun 7;8(1):8713. PubMed PMID: 29880863
  • McGraw MD, Dysart MM, Hendry-Hofer TB, Houin PR, Rioux JS, Garlick RB, Loader JE, Smith R, Paradiso DC, Holmes WW, Anderson DR, White CW, Veress LA. Bronchiolitis Obliterans and Pulmonary Fibrosis after Sulfur Mustard Inhalation in Rats. Am J Respir Cell Mol Biol. 2018 Jun;58(6):696-705. PubMed PMID: 29314868
  • Okponyia OC, McGraw MD, Dysart MM, Garlick RB, Rioux JS, Murphy AL, Roe GB, White CW, Veress LA. Oxygen Administration Improves Survival but Worsens Cardiopulmonary Functions in Chlorine-exposed Rats. Am J Respir Cell Mol Biol. 2018 Jan;58(1):107-116. PubMed PMID: 28846437
  • McGraw MD, Osborne CM, Mastej EJ, Di Paola JA, Anderson DR, Holmes WW, Paradiso DC, Garlick RB, Hendry-Hofer TB, Rancourt RC, Smith RW, Burns C, Roe GB, Rioux JS, White CW, Veress LA. Editor's Highlight: Pulmonary Vascular Thrombosis in Rats Exposed to Inhaled Sulfur Mustard. Toxicol Sci. 2017 Oct 1;159(2):461-469. PubMed PMID: 28962529
  • Summerhill EM, Hoyle GW, Jordt SE, Jugg BJ, Martin JG, Matalon S, Patterson SE, Prezant DJ, Sciuto AM, Svendsen ER, White CW, Veress LA. An Official American Thoracic Society Workshop Report: Chemical Inhalational Disasters. Biology of Lung Injury, Development of Novel Therapeutics, and Medical Preparedness. Ann Am Thorac Soc. 2017 Jun;14(6):1060-1072. PubMed PMID: 28418689
  • McGraw MD, Rioux JS, Garlick RB, Rancourt RC, White CW, Veress LA. From the Cover: ImpairedProliferation and Differentiation of the Conducting Airway Epithelium Associated With Bronchiolitis Obliterans After Sulfur Mustard Inhalation Injury in Rats. Toxicol Sci. 2017 Jun 1;157(2):399-409. PubMed PMID: 28402575
  • Ghosh M, Ahmad S, White CW, Reynolds SD. Transplantation of Airway Epithelial Stem/Progenitor Cells: A Future for Cell-based Therapy. Am J Respir Cell Mol Biol. 2016 Sep 15. [Epub ahead of print] PubMed PMID: 27632244
  • McElroy CS, Min E, Huang J, Loader JE, Hendry-Hofer TB, Garlick RB, Rioux JS, Veress LA, Smith R, Osborne C, Anderson DR, Holmes WW, Paradiso DC, White CW, Day BJ. Catalytic Antioxidant Rescue of Inhaled Sulfur Mustard Toxicity. Toxicol Sci. 2016 Sep 7. [Epub ahead of print] PubMed PMID: 27605419
  • White CW, Rancourt RC, Veress LA. Sulfur mustard inhalation: mechanisms of injury, alteration of coagulation, and fibrinolytic therapy. Ann N Y Acad Sci. 2016 Aug;1378(1):87-95. PubMed PMID: 27384912
  • Veress LA, Anderson DR, Hendry-Hofer TB, Houin PR, Rioux JS, Garlick RB, Loader JE, Paradiso DC, Smith RW, Rancourt RC, Holmes WW, White CW. Airway tissue plasminogen activator prevents acute mortality due to lethal sulfur mustard inhalation. Toxicol Sci. 2015 Jan;143(1):178-84. PubMed PMID: 25331496
  • Gabehart K, Correll KA, Loader JE, White CW, Dakhama A. The lung response to ozone is determined by age and is partially dependent on toll-Like receptor 4. Respir Res. 2015 Sep 26;16(1):117. PubMed PMID: 26410792
  • Kumar D, Tewari-Singh N, Agarwal C, Jain AK, Inturi S, Kant R, White CW, Agarwal R. Nitrogen mustard exposure of murine skin induces DNA damage, oxidative stress and activation of MAPK/Akt-AP1 pathway leading to induction of inflammatory and proteolytic mediators. Toxicol Lett. 2015 Jun 15;235(3):161-71. PubMed PMID: 25891025
  • Goswami DG, Kumar D, Tewari-Singh N, Orlicky DJ, Jain AK, Kant R, Rancourt RC, Dhar D, Inturi S, Agarwal C, White CW, Agarwal R. Topical nitrogen mustard exposure causes systemic toxic effects in mice. Exp Toxicol Pathol. 2015 Feb;67(2):161-70. PubMed PMID: 25481215
  • Jain AK, Tewari-Singh N, Inturi S, Kumar D, Orlicky DJ, Agarwal C, White CW, Agarwal R. Flavanone silibinin treatment attenuates nitrogen mustard-induced toxic effects in mouse skin. Toxicol Appl Pharmacol. 2015 May 15;285(1):71-8. PubMed PMID: 25791923
  • Veress LA, Anderson DR, Hendry-Hofer TB, Houin PR, Rioux JS, Garlick RB, Loader JE, Paradiso DC, Smith RW, Rancourt RC, Holmes WW, White CW. Airway tissue plasminogen activator prevents acute mortality due to lethal sulfur mustard inhalation. Toxicol Sci. 2015 Jan;143(1):178-84. PubMed PMID: 25331496
  • Ahmad S, Ahmad A, Hendry-Hofer TB, Loader JE, Claycomb WC, Mozziconacci O, Schöneich C, Reisdorph N, Powell RL, Chandler JD, Day BJ, Veress LA, White CW. Sarcoendoplasmic reticulum Ca(2 ) ATPase. A critical target in chlorine inhalation-induced cardiotoxicity. Am J Respir Cell Mol Biol. 2015 Apr;52(4):492-502. PubMed PMID: 25188881
  • Gabehart K, Correll KA, Loader JE, White CW, Dakhama A. The lung response to ozone is determined by age and is partially dependent on toll-Like receptor 4. Respir Res. 2015 Sep 26;16:117. PubMed PMID: 26410792
  • Zaky A, Bradley WE, Lazrak A, Zafar I, Doran S, Ahmad A, White CW, Dell'Italia LJ, Matalon S, Ahmad S. Chlorine inhalation-induced myocardial depression and failure. Physiol Rep. 2015 Jun;3(6). PubMed PMID: 26109193
  • Kumar D, Tewari-Singh N, Agarwal C, Jain AK, Inturi S, Kant R, White CW, Agarwal R. Nitrogen mustard exposure of murine skin induces DNA damage, oxidative stress and activation of MAPK/Akt-AP1 pathway leading to induction of inflammatory and proteolytic mediators. Toxicol Lett. 2015 Jun 15;235(3):161-71. PubMed PMID: 25891025
  • Jain AK, Tewari-Singh N, Inturi S, Kumar D, Orlicky DJ, Agarwal C, White CW, Agarwal R. Flavanone silibinin treatment attenuates nitrogen mustard-induced toxic effects in mouse skin. Toxicol Appl Pharmacol. 2015 May 15;285(1):71-8. PubMed PMID: 25791923
  • Goswami DG, Kumar D, Tewari-Singh N, Orlicky DJ, Jain AK, Kant R, Rancourt RC, Dhar D, Inturi S, Agarwal C, White CW, Agarwal R. Topical nitrogen mustard exposure causes systemic toxic effects in mice. Exp Toxicol Pathol. 2015 Feb;67(2):161-70. PubMed PMID: 25481215
  • Houin PR, Veress LA, Rancourt RC, Hendry-Hofer TB, Loader JE, Rioux JS, Garlick RB, White CW. Intratracheal heparin improves plastic bronchitis due to sulfur mustard analog. Pediatr Pulmonol. 2015 Feb;50(2):118-26. PubMed PMID: 24692161
  • Veress LA, Anderson DR, Hendry-Hofer TB, Houin PR, Rioux JS, Garlick RB, Loader JE, Paradiso DC, Smith RW, Rancourt RC, Holmes WW, White CW. Airway tissue plasminogen activator prevents acute mortality due to lethal sulfur mustard inhalation. Toxicol Sci. 2015 Jan;143(1):178-84. PubMed PMID: 25331496
  • Ahmad S, Ahmad A, Hendry-Hofer TB, Loader JE, Claycomb WC, Mozziconacci O, Schöneich C, Reisdorph N, Powell RL, Chandler JD, Day BJ, Veress LA, White CW. Sarcoendoplasmic reticulum Ca(2 ) ATPase. A critical target in chlorine inhalation-induced cardiotoxicity. Am J Respir Cell Mol Biol. 2015 Apr;52(4):492-502. PubMed PMID: 25188881
  • Houin PR, Veress LA, Rancourt RC, Hendry-Hofer TB, Loader JE, Rioux JS, Garlick RB, White CW. Intratracheal heparin improves plastic bronchitis due to sulfur mustard analog. Pediatr Pulmonol. 2015 Feb;50(2):118-26. PubMed PMID: 24692161
  • Zaky A, Bradley WE, Lazrak A, Zafar I, Doran S, Ahmad A, White CW, Dell'Italia LJ, Matalon S, Ahmad S. Chlorine inhalation-induced myocardial depression and failure. Physiol Rep. 2015 Jun;3(6). PubMed PMID: 26109193
  • Deterding RR, White CW. Humidifier and Environmental "chILD" Risks. Am J Respir Crit Care Med. 2014 Jan 1;189(1):10-2. PubMed PMID: 24381989
  • Gabehart K, Correll KA, Yang J, Collins ML, Loader JE, Leach S, White CW, Dakhama A. Transcriptome profiling of the newborn mouse lung response to acute ozone exposure. Toxicol Sci. 2014 Mar;138(1):175-90. PubMed PMID: 24336422
  • Jain AK, Tewari-Singh N, Inturi S, Orlicky DJ, White CW, Agarwal R. Histopathological and immunohistochemical evaluation of nitrogen mustard-induced cutaneous effects in SKH-1 hairless and C57BL/6 mice. Exp Toxicol Pathol. 2014 Mar;66(2-3):129-38. PubMed PMID: 24373750
  • Deterding RR, White CW. Humidifier and environmental "chILD" risks. Am J Respir Crit Care Med. 2014 Jan 1;189(1):10-2. PubMed PMID: 24381989
  • Tewari-Singh N, Jain AK, Orlicky DJ, White CW, Agarwal R. Cutaneous injury-related structural changes and their progression following topical nitrogen mustard exposure in hairless and haired mice. PLoS One. 2014;9(1):e85402. PubMed PMID: 24416404
  • Jain AK, Tewari-Singh N, Inturi S, Orlicky DJ, White CW, Agarwal R. Myeloperoxidase deficiency attenuates nitrogen mustard-induced skin injuries. Toxicology. 2014 Jun 5;320:25-33. PubMed PMID: 24631667
  • Houin PR, Veress LA, Rancourt RC, Hendry-Hofer TB, Loader JE, Rioux JS, Garlick RB, White CW. Intratracheal heparin improves plastic bronchitis due to sulfur mustard analog. Pediatr Pulmonol. 2014 Apr 1. [Epub ahead of print] PubMed PMID: 24692161
  • Inturi S, Tewari-Singh N, Agarwal C, White CW, Agarwal R. Activation of DNA damage repair pathways in response to nitrogen mustard-induced DNA damage and toxicity in skin keratinocytes. Mutat Res Fundam Mol Mech Mutagen. 2014 Apr 13;763-764C:53-63. [Epub ahead of print] PubMed PMID: 24732344
  • Rancourt RC, Ahmad A, Veress LA, Rioux JS, Garlick RB, White CW. Antifibrinolytic mechanisms in acute airway injury after sulfur mustard analog inhalation. Am J Respir Cell Mol Biol. 2014 Oct;51(4):559-67. PubMed PMID: 24796565
  • Tewari-Singh N, Inturi S, Jain AK, Agarwal C, Orlicky DJ, White CW, Agarwal R, Day BJ. Catalytic antioxidant AEOL 10150 treatment ameliorates sulfur mustard analog 2-chloroethyl ethyl sulfide-associated cutaneous toxic effects. Free Radic Biol Med. 2014 Jul;72:285-95. PubMed PMID: 24815113
  • Ahmad S, Ahmad A, Neeves KB, Hendry-Hofer T, Loader JE, White CW, Veress L. In vitro cell culture model for toxic inhaled chemical testing. J Vis Exp. 2014 May 8;(87). PubMed PMID: 24837339
  • Ahmad S, Ahmad A, Hendry-Hofer TB, Loader JE, Claycomb WC, Mozziconacci O, Schöneich C, Reisdorph N, Powell RL, Chandler JD, Day BJ, Veress LA, White CW. SERCA: A Critical Target in Chlorine Inhalation-induced Cardiotoxicity. Am J Respir Cell Mol Biol. 2014 Sep 4. [Epub ahead of print] PubMed PMID: 25188881
  • Goswami DG, Kumar D, Tewari-Singh N, Orlicky DJ, Jain AK, Kant R, Rancourt RC, Dhar D, Inturi S, Agarwal C, White CW, Agarwal R. Topical nitrogen mustard exposure causes systemic toxic effects in mice. Exp Toxicol Pathol. 2014 Dec 3. [Epub ahead of print] PubMed PMID: 25481215
  • Ahmad S, Ahmad A, Neeves KB, Hendry-Hofer T, Loader JE, White CW, Veress L. In vitro cell culture model for toxic inhaled chemical testing. J Vis Exp. 2014 May 8;(87). PubMed PMID: 24837339
  • Tewari-Singh N, Inturi S, Jain AK, Agarwal C, Orlicky DJ, White CW, Agarwal R, Day BJ. Catalytic antioxidant AEOL 10150 treatment ameliorates sulfur mustard analog 2-chloroethyl ethyl sulfide-associated cutaneous toxic effects. Free Radic Biol Med. 2014 Jul;72:285-95. PubMed PMID: 24815113
  • Rancourt RC, Ahmad A, Veress LA, Rioux JS, Garlick RB, White CW. Antifibrinolytic mechanisms in acute airway injury after sulfur mustard analog inhalation. Am J Respir Cell Mol Biol. 2014 Oct;51(4):559-67. PubMed PMID: 24796565
  • Inturi S, Tewari-Singh N, Agarwal C, White CW, Agarwal R. Activation of DNA damage repair pathways in response to nitrogen mustard-induced DNA damage and toxicity in skin keratinocytes. Mutat Res. 2014 May-Jun;763-764:53-63. PubMed PMID: 24732344
  • Cheung AW, White CW, Davis MK, Freed DH. Short-term mechanical circulatory support for recovery from acute right ventricular failure: clinical outcomes. J Heart Lung Transplant. 2014 Aug;33(8):794-9. PubMed PMID: 24726682
  • Jain AK, Tewari-Singh N, Inturi S, Orlicky DJ, White CW, Agarwal R. Myeloperoxidase deficiency attenuates nitrogen mustard-induced skin injuries. Toxicology. 2014 Jun 5;320:25-33. PubMed PMID: 24631667
  • Deterding RR, White CW. Humidifier and environmental "chILD" risks. Am J Respir Crit Care Med. 2014 Jan 1;189(1):10-2. PubMed PMID: 24381989
  • Jain AK, Tewari-Singh N, Inturi S, Orlicky DJ, White CW, Agarwal R. Histopathological and immunohistochemical evaluation of nitrogen mustard-induced cutaneous effects in SKH-1 hairless and C57BL/6 mice. Exp Toxicol Pathol. 2014 Mar;66(2-3):129-38. PubMed PMID: 24373750
  • Gabehart K, Correll KA, Yang J, Collins ML, Loader JE, Leach S, White CW, Dakhama A. Transcriptome profiling of the newborn mouse lung response to acute ozone exposure. Toxicol Sci. 2014 Mar;138(1):175-90. PubMed PMID: 24336422
  • Ahmad S, Ahmad A, Rancourt RC, Neeves KB, Loader JE, Hendry-Hofer T, Di Paola J, Reynolds SD, White CW. Tissue Factor Signals Airway Epithelial Basal Cell Survival via Coagulation and Protease-Activated Receptor Isoforms 1 and 2. Am J Respir Cell Mol Biol. 2013 Jan;48(1):94-104. PubMed PMID: 23065128
  • Del Rosario MA, Bender BG, White CW. Suicidal ideation and thought disorder associated with the formoterol component of combined asthma medication. Pediatr Pulmonol. 2013 Jan;48(1):102-3. PubMed PMID: 22489078
  • del Rosario MA, Bender BG, White CW. Suicidal ideation and thought disorder associated with the formoterol component of combined asthma medication. Pediatr Pulmonol. 2013 Jan;48(1):102-3. PubMed PMID: 22489078
  • Ahmad S, Ahmad A, Rancourt RC, Neeves KB, Loader JE, Hendry-Hofer T, Di Paola J, Reynolds SD, White CW. Tissue factor signals airway epithelial basal cell survival via coagulation and protease-activated receptor isoforms 1 and 2. Am J Respir Cell Mol Biol. 2013 Jan;48(1):94-104. PubMed PMID: 23065128
  • Veress LA, Hendry-Hofer TB, Loader JE, Rioux JS, Garlick RB, White CW. Tissue plasminogen activator prevents mortality from sulfur mustard analog-induced airway obstruction. Am J Respir Cell Mol Biol. 2013 Apr;48(4):439-47. PubMed PMID: 23258228
  • Ahmad A, Ahmad S, Malcolm KC, Miller SM, Hendry-Hofer T, Schaack JB, White CW. Differential regulation of pulmonary vascular cell growth by hypoxia-inducible transcription factor-1a and hypoxia-inducible transcription factor-2a. Am J Respir Cell Mol Biol. 2013 Jul;49(1):78-85. PubMed PMID: 23492195
  • Ahmad A, Schaack JB, White CW, Ahmad S. Adenosine A2A receptor-dependent proliferation of pulmonary endothelial cells is mediated through calcium mobilization, PI3-kinase and ERK1/2 pathways. Biochem Biophys Res Commun. 2013 May 10;434(3):566-71. PubMed PMID: 23583199
  • Rancourt RC, Veress LA, Ahmad A, Hendry-Hofer TB, Rioux JS, Garlick RB, White CW. Tissue factor pathway inhibitor prevents airway obstruction, respiratory failure and death due to sulfur mustard analog inhalation. Toxicol Appl Pharmacol. 2013 Oct 1;272(1):86-95. PubMed PMID: 23727623
  • Tewari-Singh N, Jain AK, Inturi S, White CW, Agarwal R. Clinically-relevant cutaneous lesions by nitrogen mustard: useful biomarkers of vesicants skin injury in SKH-1 hairless and C57BL/6 mice. PLoS One. 2013;8(6):e67557. PubMed PMID: 23826320
  • Inturi S, Tewari-Singh N, Jain AK, Roy S, White CW, Agarwal R. Absence of a p53 allele delays nitrogen mustard-induced early apoptosis and inflammation of murine skin. Toxicology. 2013 Sep 15;311(3):184-90. PubMed PMID: 23845566
  • Ghosh M, Ahmad S, Jian A, Li B, Smith RW, Helm KM, Seibold MA, Groshong SD, White CW, Reynolds SD. Human Tracheobronchial Basal Cells. Normal versus Remodeling/Repairing Phenotypes In Vivo and In Vitro. Am J Respir Cell Mol Biol. 2013 Dec;49(6):1127-34. PubMed PMID: 23927678
  • Gabehart K, Correll KA, Yang J, Collins ML, Loader JE, Leach S, White CW, Dakhama A. Transcriptome profiling of the newborn mouse lung response to acute ozone exposure. Toxicol Sci. 2013 Dec 12. [Epub ahead of print] PubMed PMID: 24336422
  • Jain AK, Tewari-Singh N, Inturi S, Orlicky DJ, White CW, Agarwal R. Histopathological and immunohistochemical evaluation of nitrogen mustard-induced cutaneous effects in SKH-1 hairless and C57BL/6 mice. Exp Toxicol Pathol. 2013 Dec 24. [Epub ahead of print] PubMed PMID: 24373750
  • Veress LA, Hendry-Hofer TB, Loader JE, Rioux JS, Garlick RB, White CW. Tissue Plasminogen Activator Prevents Mortality from Sulfur Mustard Analog-Induced Airway Obstruction. Am J Respir Cell Mol Biol. 2012 Dec 20. [Epub ahead of print] PubMed PMID: 23258228
  • Tewari-Singh N, Jain AK, Inturi S, Agarwal C, White CW, Agarwal R. Silibinin attenuates sulfur mustard analog-induced skin injury by targeting multiple pathways connecting oxidative stress and inflammation. PLoS One. 2012;7(9):e46149. PubMed PMID: 23029417
  • Ahmad S, Raemy DO, Loader JE, Kailey JM, Neeves KB, White CW, Ahmad A, Gehr P, Rothen-Rutishauser BM. Interaction and localization of synthetic nanoparticles in healthy and cystic fibrosis airway epithelial cells: effect of ozone exposure. J Aerosol Med Pulm Drug Deliv. 2012 Feb;25(1):7-15. PubMed PMID: 22007674
  • Rancourt RC, Veress LA, Guo X, Jones TN, Hendry-Hofer TB, White CW. Airway tissue factor-dependent coagulation activity in response to sulfur mustard analog 2-chloroethyl ethyl sulfide. Am J Physiol Lung Cell Mol Physiol. 2012 Jan 1;302(1):L82-92. PubMed PMID: 21964405
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Professional Memberships

  • American Thoracic Society (ATS), Member
  • American Physiologic Society (APS), Member
  • Society for Free Radical Biology and Medicine, Member

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation
  • Children's Hospital Colorado

Specialty Information

Specialties
  • Pediatric Pulmonology, Board Certification (1986, 2014)
  • Pediatrics, Board Certification (1983)
Conditions & Treatments
  • Lungs and Breathing - Pulmonary Disorders
  • Lungs and Breathing - Lung Disease
  • Lungs and Breathing - Interstitial Lung Disease
  • Lungs and Breathing - Granulomatous Lung Disease
  • Lungs and Breathing
  • Lungs and Breathing - Cystic Fibrosis
  • Lungs and Breathing - Pulmonary Hypertension
  • Lungs and Breathing - Asthma
  • Immune System - Allergies
  • Immune System
Clinical Interests
Asthma, respiratory infections, airway disorders, chronic lung diseases, and toxic chemical inhalation

General Information

Medical Schools:
  • MD, Baylor College of Medicine (1978)
Undergraduate Schools:
  • BA, Earlham College (IN) (1974)
Internships:
  • Baylor College of Medicine Program (1979)
Residency Programs:
  • Baylor College of Medicine Program, Chief Resident, Pediatrics (1981)
Fellowships:
  • University of Colorado, Pediatric Pulmonology (1984)
Languages: English, Spanish
Department: Pediatrics-Pulmonary Medicine
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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