Nancy Hadley-Miller, MD
Professor, Orthopedics

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Medical School:
  • MD, University of Maryland School of Medicine (1982)
Graduate School :
  • MS, Georgetown University (1978)
Undergraduate School:
  • BA, Harvard University (MA) (1976)
Internship:
  • Union Memorial Hospital Program (1983)
Residency:
  • Boston University Medical Center Program, Orthopedics (1987)
Fellowships:
  • University of Iowa Hospitals and Clinics Program, Pediatric Orthopedics (1988)
Languages: English
Department: Orthopedics

Publications

  • Terhune E, Heyn P, Piper C, Wethey C, Monley A, Cuevas M, Hadley Miller N. Association between genetic polymorphisms and risk of adolescent idiopathic scoliosis in case-control studies: a systematic review. J Med Genet. 2024 Jan 19;61(2):196-206. PubMed PMID: 37696603
  • Cuevas M, Terhune E, Wethey C, James M, Netsanet R, Grofova D, Monley A, Hadley Miller N. Cytoskeletal Keratins Are Overexpressed in a Zebrafish Model of Idiopathic Scoliosis. Genes (Basel). 2023 May 9;14(5). PubMed PMID: 37239418
  • Yamamura MK, Carry PM, Gibly RF, Holmes K, Ogilvie B, Phillips A, Georgopoulos G, Miller NH, Payne KA. Epidemiology of Physeal Fractures and Clinically Significant Growth Disturbances Affecting the Distal Tibia, Proximal Tibia, and Distal Femur: A Retrospective Cohort Study. J Am Acad Orthop Surg. 2023 Jun 1;31(11):e507-e515. PubMed PMID: 37054395
  • Brazell CJ, Carry PM, Holmes KS, Salton RL, Hadley-Miller N, Georgopoulos G. Pediatric and Adult Fracture Incidence: A Decreasing Trend With Increasing Hospital Admissions. Orthopedics. 2023 Nov-Dec;46(6):e369-e375. PubMed PMID: 37018620
  • Salton RL, Carry PM, Hadley-Miller N, Murphy-Zane MS, Brazell C, Novais E, Georgopoulos G. Prediction of Late Dysplasia Based on Ultrasound and Plain X-Ray at 6 Months. J Pediatr Orthop. 2023 Feb 1;43(2):99-104. PubMed PMID: 36607921
  • Murphy-Zane MS, Carry PM, Salton RL, Hadley Miller N, Holmes K, Freeman T, Belton M, Kohuth B, Burke D, Georgopoulos G. Application of Accepted Use Criteria for the Treatment of Developmental Dysplasia of the Hip Decreases the Number of Infants Treated With a Pavlik Harness. J Pediatr Orthop. 2023 Feb 1;43(2):e138-e143. PubMed PMID: 36376269
  • Shaw KG, Salton RL, Carry P, Hadley-Miller N, Georgopoulos G. Multi-day delay to care identified in pediatric trauma cases during COVID-19. J Pediatr Orthop B. 2022 Jan 1;31(1):e56-e64. PubMed PMID: 34406164
  • Murphy-Zane MS, Carry PM, Salton RL, Hadley Miller N, Holmes K, Freeman T, Belton M, Kohuth B, Burke D, Georgopoulos G. Application of Accepted Use Criteria for the Treatment of Developmental Dysplasia of the Hip Decreases the Number of Infants Treated With a Pavlik Harness. J Pediatr Orthop. 2022 Nov 15. [Epub ahead of print] PubMed PMID: 36376269
  • Yu Y, Fischenich KM, Schoonraad SA, Weatherford S, Uzcategui AC, Eckstein K, Muralidharan A, Crespo-Cuevas V, Rodriguez-Fontan F, Killgore JP, Li G, McLeod RR, Miller NH, Ferguson VL, Bryant SJ, Payne KA. A 3D printed mimetic composite for the treatment of growth plate injuries in a rabbit model. NPJ Regen Med. 2022 Oct 19;7(1):60. PubMed PMID: 36261516
  • Giampietro PF, Hadley-Miller N, Raggio CL. Overview of Gene Special Issue "Genetic Conditions Affecting the Skeleton: Congenital, Idiopathic Scoliosis and Arthrogryposis". Genes (Basel). 2022 Jul 4;13(7). PubMed PMID: 35885977
  • Fuchs JR, Gibly RF, Erickson CB, Thomas SM, Hadley Miller N, Payne KA. Analysis of Physeal Fractures from the United States National Trauma Data Bank. Children (Basel). 2022 Jun 18;9(6). PubMed PMID: 35740851
  • Terhune EA, Heyn PC, Piper CR, Hadley-Miller N. Genetic variants associated with the occurrence and progression of adolescent idiopathic scoliosis: a systematic review protocol. Syst Rev. 2022 Jun 9;11(1):118. PubMed PMID: 35681176
  • Terhune EA, Monley AM, Cuevas MT, Wethey CI, Gray RS, Hadley-Miller N. Genetic animal modeling for idiopathic scoliosis research: history and considerations. Spine Deform. 2022 Sep;10(5):1003-1016. PubMed PMID: 35430722
  • Gibly RF, Georgopoulos G, Carry PM, Miller NH. Lower extremity physeal fractures and post-traumatic surgical deformities; National Trauma Data Bank and institutional cohorts. J Clin Orthop Trauma. 2022 Apr;27:101827. PubMed PMID: 35310787
  • Eckstein KN, Thomas SM, Scott AK, Neu CP, Hadley-Miller NA, Payne KA, Ferguson VL. The heterogeneous mechanical properties of adolescent growth plate cartilage: A study in rabbit. J Mech Behav Biomed Mater. 2022 Apr;128:105102. PubMed PMID: 35203020
  • Salton RL, Carry P, Freeman T, Holmes K, Miller NH, Kohuth B, Burke D, Belton M, Murphy-Zane MS, Georgopoulos G. Twelve-week standard of care protocol longer than median time to normalization among IIc hips treated with Pavlik harness. J Pediatr Orthop B. 2022 Jul 1;31(4):313-318. PubMed PMID: 35102060
  • Shaw KG, Salton RL, Carry P, Hadley-Miller N, Georgopoulos G. Multi-day delay to care identified in pediatric trauma cases during COVID-19. J Pediatr Orthop B. 2022 Jan 1;31(1):e56-e64. PubMed PMID: 34406164
  • Ramalingam WG, Carry P, Brazell C, Calkins R, Linza-Moscati S, Stoneback J, Miller NH. Outcomes of displaced adolescent distal third tibia fractures: can we do better?. J Pediatr Orthop B. 2022 Mar 1;31(2):e147-e153. PubMed PMID: 34285160
  • Tun MH, Borg B, Godfrey M, Hadley-Miller N, Chan ED. Respiratory manifestations of Marfan syndrome: a narrative review. J Thorac Dis. 2021 Oct;13(10):6012-6025. PubMed PMID: 34795948
  • Carry PM, Terhune EA, Trahan GD, Vanderlinden LA, Wethey CI, Ebrahimi P, McGuigan F, Åkesson K, Hadley-Miller N. Severity of Idiopathic Scoliosis Is Associated with Differential Methylation: An Epigenome-Wide Association Study of Monozygotic Twins with Idiopathic Scoliosis. Genes (Basel). 2021 Jul 30;12(8). PubMed PMID: 34440365
  • Tang NLS, Dobbs MB, Gurnett CA, Qiu Y, Lam TP, Cheng JCY, Hadley-Miller N. A Decade in Review after Idiopathic Scoliosis Was First Called a Complex Trait-A Tribute to the Late Dr. Yves Cotrel for His Support in Studies of Etiology of Scoliosis. Genes (Basel). 2021 Jul 1;12(7). PubMed PMID: 34356049
  • Ramalingam WG, Carry P, Brazell C, Calkins R, Linza-Moscati S, Stoneback J, Miller NH. Outcomes of displaced adolescent distal third tibia fractures: can we do better?. J Pediatr Orthop B. 2021 Jul 19. [Epub ahead of print] PubMed PMID: 34285160
  • Terhune EA, Wethey CI, Cuevas MT, Monley AM, Baschal EE, Bland MR, Baschal R, Trahan GD, Taylor MRG, Jones KL, Hadley Miller N. Whole Exome Sequencing of 23 Multigeneration Idiopathic Scoliosis Families Reveals Enrichments in Cytoskeletal Variants, Suggests Highly Polygenic Disease. Genes (Basel). 2021 Jun 16;12(6). PubMed PMID: 34208743
  • Terhune EA, Cuevas MT, Monley AM, Wethey CI, Chen X, Cattell MV, Bayrak MN, Bland MR, Sutphin B, Trahan GD, Taylor MRG, Niswander LA, Jones KL, Baschal EE, Antunes L, Dobbs M, Gurnett C, Appel B, Gray R, Hadley Miller N. Mutations in KIF7 implicated in idiopathic scoliosis in humans and axial curvatures in zebrafish. Hum Mutat. 2021 Apr;42(4):392-407. PubMed PMID: 33382518
  • Erickson CB, Newsom JP, Fletcher NA, Yu Y, Rodriguez-Fontan F, Weatherford SA, Hadley-Miller N, Krebs MD, Payne KA. Anti-VEGF antibody delivered locally reduces bony bar formation following physeal injury in rats. J Orthop Res. 2021 Aug;39(8):1658-1668. PubMed PMID: 33179297
  • 18. Genetic Variants Associated with the Occurrence and Progression of Adolescent Idiopathic Scoliosis: A Systematic Review Protocol. Terhune EA, Heyn PC, Piper CR, Hadley-Miller N. 26 May 2021. PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-540418/v1]
  • Erickson CB, Newsom JP, Fletcher NA, Yu Y, Rodriguez-Fontan F, Weatherford SA, Hadley-Miller N, Krebs MD, Payne KA. Anti-VEGF antibody delivered locally reduces bony bar formation following physeal injury in rats. J Orthop Res. 2020 Nov 12. [Epub ahead of print] PubMed PMID: 33179297
  • Carry PM, Duke VR, Brazell CJ, Stence N, Scholes M, Rousie DL, Hadley Miller N. Lateral semi-circular canal asymmetry in females with idiopathic scoliosis. PLoS One. 2020;15(4):e0232417. PubMed PMID: 32349123
  • Erickson CB, Newsom JP, Fletcher NA, Feuer ZM, Yu Y, Rodriguez-Fontan F, Hadley Miller N, Krebs MD, Payne KA. In vivo degradation rate of alginate-chitosan hydrogels influences tissue repair following physeal injury. J Biomed Mater Res B Appl Biomater. 2020 Aug;108(6):2484-2494. PubMed PMID: 32034881
  • Holmes K, Gralla J, Brazell C, Carry P, Tong S, Miller NH, Georgopoulos G. Fassier-Duval Rod Failure: Is It Related to Positioning in the Distal Epiphysis?. J Pediatr Orthop. 2020 Sep;40(8):448-452. PubMed PMID: 32032215
  • Hadley-Miller N, Carry PM, Brazell CJ, Holmes KS, Georgopoulos G. Trends in Trampoline Fractures: 2008-2017. Pediatrics. 2020 Jan;145(1). PubMed PMID: 31826929
  • 101. Implementation of a Ponseti Clubfoot Program Improves Patient Outcomes by Decreasing Major Surgery: A Quality Improvement Initiative. Carry, PM, Graham, S, Whalen, K, Burke, D, Baschal, R, Holmes, KS, Kohuth, B, Georgopoulos, G, Miller, NH. Pediatric Quality and Safety, 6(5): October 2020.
  • Mutations in KIF7, a Primary Cilia Gene, Implicated in Idiopathic Scoliosis in Humans and Axial Curvatures in Zebrafish Accepted 12/11/2020 to “Human Mutation” as a Research Article Elizabeth A. Terhune*1, Melissa T. Cuevas*1, Anna M. Monley1,2, Cambria I. Wethey1, Xiaomi Chen1, Maria V. Cattel1, Melisa N. Bayrak8, Morgan R. Bland1, Brittan Sutphin1, G. Devon Trahan3, Matthew R.G. Taylor4, Lee A. Niswander3,5, Kenneth L. Jones3, Erin E. Baschal1, Lilian Antunes6, Matthew Dobbs6, Christina Gurnett7, Bruce Appel5, Ryan Gray8, Nancy Hadley Miller1,2
  • "Tonnis Angle and Acetabular Retroversion Measurements in Asymptomatic Hips are Predictive of Future Hip Pain" b. Manuscript number - JAAOSGlobal-D-20-00213 c. Acceptance date - Oct 21, 2020
  • Yu Y, Rodriguez-Fontan F, Eckstein K, Muralidharan A, Uzcategui AC, Fuchs JR, Weatherford S, Erickson CB, Bryant SJ, Ferguson VL, Hadley Miller N, Li G, Payne KA. Rabbit Model of Physeal Injury for the Evaluation of Regenerative Medicine Approaches. Tissue Eng Part C Methods. 2019 Dec;25(12):701-710. PubMed PMID: 31552802
  • Spahn KM, Mickel T, Carry PM, Brazell CJ, Whalen K, Georgopoulos G, Miller NH. Fassier-Duval Rods are Associated With Superior Probability of Survival Compared With Static Implants in a Cohort of Children With Osteogenesis Imperfecta Deformities. J Pediatr Orthop. 2018 Dec 26. [Epub ahead of print] PubMed PMID: 30589679
  • Tetreault A, Ramalingam W, Black J, Miller NH, Donaldson N. Osteosarcoma in an Adolescent with Kniest Dysplasia: A Case Report. JBJS Case Connect. 2018 Oct-Dec;8(4):e78. PubMed PMID: 30303846
  • Haller G, McCall K, Jenkitkasemwong S, Sadler B, Antunes L, Nikolov M, Whittle J, Upshaw Z, Shin J, Baschal E, Cruchaga C, Harms M, Raggio C, Morcuende JA, Giampietro P, Miller NH, Wise C, Gray RS, Solnica-Krezel L, Knutson M, Dobbs MB, Gurnett CA. A missense variant in SLC39A8 is associated with severe idiopathic scoliosis. Nat Commun. 2018 Oct 9;9(1):4171. PubMed PMID: 30301978
  • Baschal EE, Terhune EA, Wethey CI, Baschal RM, Robinson KD, Cuevas MT, Pradhan S, Sutphin BS, Taylor MRG, Gowan K, Pearson CG, Niswander LA, Jones KL, Miller NH. Idiopathic Scoliosis Families Highlight Actin-Based and Microtubule-Based Cellular Projections and Extracellular Matrix in Disease Etiology. G3 (Bethesda). 2018 Jul 31;8(8):2663-2672. PubMed PMID: 29930198
  • Carry PM, Nguyen AK, Merritt GR, Ciarallo C, Chatterjee D, Park J, Miller NH, Scott FA. Prevalence of Persistent Median Arteries in the Pediatric Population on Ultrasonography. J Ultrasound Med. 2018 Sep;37(9):2235-2242. PubMed PMID: 29480530
  • Chang FM, May A, Faulk LW, Flynn K, Miller NH, Rhodes JT, Zhaoxing P, Novais EN. Outcomes of Isolated Varus Derotational Osteotomy in Children With Cerebral Palsy Hip Dysplasia and Predictors of Resubluxation. J Pediatr Orthop. 2018 May Jun;38(5):274-278. PubMed PMID: 27280898
  • Stoneback JW, Carry PM, Flynn K, Pan Z, Sink EL, Miller NH. Clinical and Radiographic Outcomes After Submuscular Plating (SMP) of Pediatric Femoral Shaft Fractures. J Pediatr Orthop. 2018 Mar;38(3):138-143. PubMed PMID: 27261971
  • Haller G, Alvarado D, Mccall K, Yang P, Cruchaga C, Harms M, Goate A, Willing M, Morcuende JA, Baschal E, Miller NH, Wise C, Dobbs MB, Gurnett CA. A polygenic burden of rare variants across extracellular matrix genes among individuals with adolescent idiopathic scoliosis. Hum Mol Genet. 2016 Jan 1;25(1):202-9. PubMed PMID: 26566670
  • Thompson ME, Kohring JM, McFann K, McNair B, Hansen JK, Miller NH. Predicting excessive hemorrhage in adolescent idiopathic scoliosis patients undergoing posterior spinal instrumentation and fusion. Spine J. 2014 Aug 1;14(8):1392-8. PubMed PMID: 24139751
  • Tepolt F, Carry PM, Heyn PC, Miller NH. Posterior sternoclavicular joint injuries in the adolescent population: a meta-analysis. Am J Sports Med. 2014 Oct;42(10):2517-24. PubMed PMID: 24569702
  • Buchan JG, Alvarado DM, Haller GE, Cruchaga C, Harms MB, Zhang T, Willing MC, Grange DK, Braverman AC, Miller NH, Morcuende JA, Tang NL, Lam TP, Ng BK, Cheng JC, Dobbs MB, Gurnett CA. Rare variants in FBN1 and FBN2 are associated with severe adolescent idiopathic scoliosis. Hum Mol Genet. 2014 Oct 1;23(19):5271-82. PubMed PMID: 24833718
  • Buchan JG, Alvarado DM, Haller G, Aferol H, Miller NH, Dobbs MB, Gurnett CA. Are copy number variants associated with adolescent idiopathic scoliosis?. Clin Orthop Relat Res. 2014 Oct;472(10):3216-25. PubMed PMID: 25005481
  • Baschal EE, Wethey CI, Swindle K, Baschal RM, Gowan K, Tang NL, Alvarado DM, Haller GE, Dobbs MB, Taylor MR, Gurnett CA, Jones KL, Miller NH. Exome Sequencing Identifies a Rare HSPG2 Variant Associated with Familial Idiopathic Scoliosis. G3 (Bethesda). 2014 Dec 12;5(2):167-74. PubMed PMID: 25504735
  • Ackerson R, Nguyen A, Carry PM, Pritchard B, Hadley-Miller N, Scott F. Intra-articular Radial Head Fractures In the Skeletally Immature Patient: Complications and Management. J Pediatr Orthop. 2014 Aug 28. [Epub ahead of print] PubMed PMID: 25171672
  • Thompson ME, Kohring JM, McFann K, McNair B, Hansen JK, Miller NH. Predicting excessive hemorrhage in adolescent idiopathic scoliosis patients undergoing posterior spinal instrumentation and fusion. Spine J. 2013 Oct 18. [Epub ahead of print] PubMed PMID: 24139751
  • Tilley MK, Justice CM, Swindle K, Marosy B, Wilson AF, Miller NH. CHD7 gene polymorphisms and familial idiopathic scoliosis. Spine (Phila Pa 1976). 2013 Oct 15;38(22):E1432-6. PubMed PMID: 23883829
  • Mueller TL, Miller NH, Baulesh DM, Hastings LH, Chang FM, Georgopoulos G, Benefield EM, Pan Z, Erickson MA. The safety of spinal pedicle screws in children ages 1 to 12. Spine J. 2013 Aug;13(8):894-901. PubMed PMID: 23523435
  • Erickson MA, Morrato EH, Campagna EJ, Elise B, Miller NH, Kempe A. Variability in spinal surgery outcomes among children's hospitals in the United States. J Pediatr Orthop. 2013 Jan;33(1):80-90. PubMed PMID: 23232385
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Professional Memberships

  • American Academy of Orthopaedic Surgeons (AAOS), Member
  • Interurban Orthopaedic Society, Member
  • Orthopaedic Research Society, Member
  • Pediatric Orthopaedic Society of North America (POSNA), Member
  • Scoliosis Research Society (SRS), Active Fellow
  • Scoliosis Association, Inc., Member
  • Colorado Orthopedic Society, Member

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Children's Hospital Colorado North Campus
469 State Highway 7
Broomfield, CO 80023
720-478-5000

Hospital Affiliation
  • Children's Hospital Colorado
Center Affiliations

Specialty Information

Specialties
  • Pediatric Orthopedics, Board Certification (2006)
  • Orthopedics, Board Certification
Conditions & Treatments
  • Surgery
  • Bones, Joints and Muscles - Scoliosis
  • Bones, Joints and Muscles - Spine Injuries
  • Bones, Joints and Muscles
Clinical Interests
Dr. Miller specializes in the care and treatment of pediatric patients with both spine and limb deformities, congenital or acquired.

Care Philosophy
Our group is committed to providing the highest quality professional and ethical care to all patients through integration of comprehensive education and exceptional musculoskeletal research.

Personal Interests
Dr. Millers interest includes the care, treatment and research for Scoliosis pediatric patients.

General Information

Medical Schools:
  • MD, University of Maryland School of Medicine (1982)
Graduate Schools:
  • MS, Georgetown University (1978)
Undergraduate Schools:
  • BA, Harvard University (MA) (1976)
Internships:
  • Union Memorial Hospital Program (1983)
Residency Programs:
  • Boston University Medical Center Program, Orthopedics (1987)
Fellowships:
  • University of Iowa Hospitals and Clinics Program, Pediatric Orthopedics (1988)
Download CV
Languages: English
Department: Orthopedics
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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