Adel Younoszai, MD
Professor, Pediatrics-Cardiology

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Medical School:
  • MD, University of Iowa Roy J. and Lucille A. Carver College of Medicine (1994)
Undergraduate School:
  • BS, University of Iowa (IA) (1989)
Internship:
  • Nationwide Children's Hospital/Ohio State University Program (1995)
Residency:
  • Nationwide Children's Hospital/Ohio State University Program, Pediatrics (1997)
Fellowships:
  • California Pacific Medical Center/University of California (San Francisco) Program, Pediatric Cardiology (2000)
Languages: English
Department: Pediatrics-Cardiology

Professional Titles

  • Professor, Pediatrics-Cardiology
  • Director of Cardiac Imaging, The Children's Hospital
  • Co-Director of the Single Ventricle Care Program
  • Associate Dean of Clinical Affairs, Child Health. The University of Colorado School of Medicine

Recognition & Awards

  • Five Star Excellence Award, Children's Hospital Colorado, (2015)
    Based on patient feedback/surveys.
  • Teacher and Mentor Excellence Award, Pediatric Cardiology Fellows, (2012)
    Voted as the best educator by pediatric cardiology fellows
  • Five Star Excellence Award, Children Hospital Colorado, (2012)
    Based on patient feedback/surveys.

Research Interests

*Long term care of the child with a Single Ventricle after the Fontan Operation *How to diagnose and evaluate Pulmonary Hypertension *The mechanics of how the heart muscle works *How normally do children with complex congenital heart disease develop motor and brain function?

Teaching

  • Professor (2006)
    School of Medicine, Pediatrics
    Congenital Heart Disease, Echocardiography, Fetal Cardiology, Myocardial Mechanics, Care of Children with Single Ventricle Hearts

Publications

  • Schäfer M, Younoszai A, Truong U, Browne LP, Mitchell MB, Jaggers J, Campbell DN, Hunter KS, Ivy DD, Di Maria MV. Influence of aortic stiffness on ventricular function in patients with Fontan circulation. J Thorac Cardiovasc Surg. 2018 Oct 5. [Epub ahead of print] PubMed PMID: 30396734
  • Lopez C, Mertens L, Dragulescu A, Landeck B, Younoszai A, Friedberg MK, Hunter K, Di Maria MV. Strain and Rotational Mechanics in Children With Single Left Ventricles After Fontan. J Am Soc Echocardiogr. 2018 Oct 18. [Epub ahead of print] PubMed PMID: 30344011
  • Mourani PM, Mandell EW, Meier M, Younoszai A, Brinton JT, Wagner BD, Arjaans S, Poindexter BB, Abman SH. Early Pulmonary Vascular Disease in Preterm Infants is Associated with Late Respiratory Outcomes in Childhood. Am J Respir Crit Care Med. 2018 Oct 10. [Epub ahead of print] PubMed PMID: 30303395
  • Di Maria MV, Brown DW, Cetta F, Ginde S, Goldberg D, Menon SC, Phelps HM, Rychik J, Schumacher KR, Thrush P, Veldtman G, Wright G, Younoszai AK. Surveillance Testing and Preventive Care After Fontan Operation: A Multi-Institutional Survey. Pediatr Cardiol. 2018 Aug 29. [Epub ahead of print] PubMed PMID: 30159585
  • Liptzin DR, Di Maria MV, Younoszai A, Narkewicz MR, Kelly SL, Wolfe KR, Veress LA. Pulmonary Screening in Subjects after the Fontan Procedure. J Pediatr. 2018 Aug;199:140-143. PubMed PMID: 29747936
  • Di Maria MV, Silverman L, Younoszai AK, Meyers ML, Capocelli KE, Narkewicz MR. Acoustic radiation force impulse of the liver after Fontan operation: Correlation with cardiopulmonary exercise test. Congenit Heart Dis. 2018 May;13(3):444-449. PubMed PMID: 29473337
  • Di Maria MV, Mulvahill M, Jaggers J, Ivy DD, Younoszai AK. Predictive value of presuperior cavopulmonary anastomosis cardiac catheterization at increased altitude. Congenit Heart Dis. 2018 Mar;13(2):311-318. PubMed PMID: 29431283
  • Jone PN, Gould R, Barrett C, Younoszai AK, Fonseca B. Data-Driven Quality Improvement Project to Increase the Value of the Congenital Echocardiographic Report. Pediatr Cardiol. 2018 Apr;39(4):726-730. PubMed PMID: 29350246
  • Boruta RJ, Miyamoto SD, Younoszai AK, Patel SS, Landeck BF 2nd. Worsening in Longitudinal Strain and Strain Rate Anticipates Development of Pediatric Transplant Coronary Artery Vasculopathy as Soon as One Year Following Transplant. Pediatr Cardiol. 2017 Sep 25. [Epub ahead of print] PubMed PMID: 28948364
  • Boruta RJ, Miyamoto SD, Younoszai AK, Patel SS, Landeck BF 2nd. Worsening in Longitudinal Strain and Strain Rate Anticipates Development of Pediatric Transplant Coronary Artery Vasculopathy as Soon as One Year Following Transplant. Pediatr Cardiol. 2017 Sep 25. [Epub ahead of print] PubMed PMID: 28948364
  • Carlton EF, Sontag MK, Younoszai A, DiMaria MV, Miller JI, Poindexter BB, Abman SH, Mourani PM. Reliability of Echocardiographic Indicators of Pulmonary Vascular Disease in Preterm Infants at Risk for Bronchopulmonary Dysplasia. J Pediatr. 2017 Jul;186:29-33. PubMed PMID: 28411949
  • Hauck A, Guo R, Ivy DD, Younoszai A. Tricuspid annular plane systolic excursion is preserved in young patients with pulmonary hypertension except when associated with repaired congenital heart disease. Eur Heart J Cardiovasc Imaging. 2016 Apr 20. [Epub ahead of print] PubMed PMID: 27099276
  • Burkett DA, Slorach C, Patel SS, Redington AN, Ivy DD, Mertens L, Younoszai AK, Friedberg MK. Impact of Pulmonary Hemodynamics and Ventricular Interdependence on Left Ventricular Diastolic Function in Children With Pulmonary Hypertension. Circ Cardiovasc Imaging. 2016 Sep;9(9). PubMed PMID: 27581953
  • Srivastava S, Allada V, Younoszai A, Lopez L, Soriano BD, Fleishman CE, Van Hoever AM, Lai WW. Determinants of Pediatric Echocardiography Laboratory Productivity: Analysis from the Second Survey of the American Society of Echocardiography Committee on Echocardiography Laboratory Productivity. J Am Soc Echocardiogr. 2016 Oct;29(10):1009-1015. PubMed PMID: 27523266
  • Hauck A, Guo R, Ivy DD, Younoszai A. Tricuspid annular plane systolic excursion is preserved in young patients with pulmonary hypertension except when associated with repaired congenital heart disease. Eur Heart J Cardiovasc Imaging. 2016 Apr 20. [Epub ahead of print] PubMed PMID: 27099276
  • Zoeller BB, Miyamoto SD, Younoszai AK, Landeck BF 2nd. Longitudinal Strain and Strain Rate Abnormalities Precede Invasive Diagnosis of Transplant Coronary Artery Vasculopathy in Pediatric Cardiac Transplant Patients. Pediatr Cardiol. 2016 Apr;37(4):656-62. PubMed PMID: 26818849
  • Zoeller BB, Miyamoto SD, Younoszai AK, Landeck BF 2nd. Longitudinal Strain and Strain Rate Abnormalities Precede Invasive Diagnosis of Transplant Coronary Artery Vasculopathy in Pediatric Cardiac Transplant Patients. Pediatr Cardiol. 2016 Apr;37(4):656-62. PubMed PMID: 26818849
  • Burkett DA, Wilson N, Mitchell MB, Younoszai AK. Acute ischaemic heart block in hypoplastic left heart syndrome. Cardiol Young. 2014 Dec 22;:1-4. [Epub ahead of print] PubMed PMID: 25531744
  • Burkett DA, Slorach C, Patel SS, Redington AN, Ivy DD, Mertens L, Younoszai AK, Friedberg MK. Impact of Pulmonary Hemodynamics and Ventricular Interdependence on Left Ventricular Diastolic Function in Children With Pulmonary Hypertension. Circ Cardiovasc Imaging. 2016 Sep;9(9). PubMed PMID: 27581953
  • Srivastava S, Allada V, Younoszai A, Lopez L, Soriano BD, Fleishman CE, Van Hoever AM, Lai WW. Determinants of Pediatric Echocardiography Laboratory Productivity: Analysis from the Second Survey of the American Society of Echocardiography Committee on Echocardiography Laboratory Productivity. J Am Soc Echocardiogr. 2016 Oct;29(10):1009-1015. PubMed PMID: 27523266
  • Zoeller BB, Miyamoto SD, Younoszai AK, Landeck BF 2nd. Longitudinal Strain and Strain Rate Abnormalities Precede Invasive Diagnosis of Transplant Coronary Artery Vasculopathy in Pediatric Cardiac Transplant Patients. Pediatr Cardiol. 2016 Apr;37(4):656-62. PubMed PMID: 26818849
  • Burkett DA, Wilson N, Mitchell MB, Younoszai AK. Acute ischaemic heart block in hypoplastic left heart syndrome. Cardiol Young. 2014 Dec 22;:1-4. [Epub ahead of print] PubMed PMID: 25531744
  • Mourani PM, Sontag MK, Younoszai A, Miller JI, Kinsella JP, Baker CD, Poindexter BB, Ingram DA, Abman SH. Early pulmonary vascular disease in preterm infants at risk for bronchopulmonary dysplasia. Am J Respir Crit Care Med. 2015 Jan 1;191(1):87-95. PubMed PMID: 25389562
  • Di Maria MV, Burkett DA, Younoszai AK, Landeck BF 2nd, Mertens L, Ivy DD, Friedberg MK, Hunter KS. Echocardiographic Estimation of Right Ventricular Stroke Work in Children with Pulmonary Arterial Hypertension: Comparison with Invasive Measurements. J Am Soc Echocardiogr. 2015 Aug 20. [Epub ahead of print] PubMed PMID: 26299333
  • Burkett DA, Slorach C, Patel SS, Redington AN, Ivy DD, Mertens L, Younoszai AK, Friedberg MK. Left Ventricular Myocardial Function in Children With Pulmonary Hypertension: Relation to Right Ventricular Performance and Hemodynamics. Circ Cardiovasc Imaging. 2015 Aug;8(8). PubMed PMID: 26259580
  • Di Maria MV, Younoszai AK, Sontag MK, Miller JI, Poindexter BB, Ingram DA, Abman SH, Mourani PM. Maturational Changes in Diastolic Longitudinal Myocardial Velocity in Preterm Infants. J Am Soc Echocardiogr. 2015 Sep;28(9):1045-52. PubMed PMID: 26025727
  • Webb MK, Auerbach SR, Younoszai AK, Patel SS, Landeck BF 2nd. Strain and Strain Rate Measured on Echocardiogram 1-3 Weeks after Starting Treatment Is Worse in Acute Dilated Cardiomyopathy Pediatric Patients with Poor Outcomes at One Year. Echocardiography. 2015 Apr 15. [Epub ahead of print] PubMed PMID: 25877880
  • Di Maria MV, Hsu HH, Al-Naami G, Gruenwald J, Kirby KS, Kirkham FJ, Cox SE, Younoszai AK. Left Ventricular Rotational Mechanics in Tanzanian Children with Sickle Cell Disease. J Am Soc Echocardiogr. 2014 Dec 30. [Epub ahead of print] PubMed PMID: 25555520
  • Jone PN, Bremen C, DiMaria M, Campbell DN, Jaggers J, Younoszai A, Ivy DD. Three-Dimensional Echocardiography Enhances Diagnostic Accuracy of Supramitral Ring. Echocardiography. 2014 Dec 12. [Epub ahead of print] PubMed PMID: 25496227
  • Mourani PM, Sontag MK, Younoszai A, Miller JI, Kinsella JP, Baker CD, Poindexter BB, Ingram DA, Abman SH. Early pulmonary vascular disease in preterm infants at risk for bronchopulmonary dysplasia. Am J Respir Crit Care Med. 2015 Jan 1;191(1):87-95. PubMed PMID: 25389562
  • Jone PN, Hinzman J, Wagner BD, Ivy DD, Younoszai A. Right Ventricular to Left Ventricular Diameter Ratio at End-Systole in Evaluating Outcomes in Children with Pulmonary Hypertension. J Am Soc Echocardiogr. 2013 Dec 7. [Epub ahead of print] PubMed PMID: 24325962
  • Cox SE, Soka D, Kirkham FJ, Newton CR, Prentice AM, Makani J, Younoszai AK. Tricuspid regurgitant jet velocity and hospitalization in Tanzanian children with sickle cell anemia. Haematologica. 2014 Jan;99(1):e1-4. PubMed PMID: 24425690
  • Di Maria MV, Hsu HH, Al-Naami G, Gruenwald J, Kirby KS, Kirkham FJ, Cox SE, Younoszai AK. Left Ventricular Rotational Mechanics in Tanzanian Children with Sickle Cell Disease. J Am Soc Echocardiogr. 2014 Dec 30. [Epub ahead of print] PubMed PMID: 25555520
  • Burkett DA, Wilson N, Mitchell MB, Younoszai AK. Acute ischaemic heart block in hypoplastic left heart syndrome. Cardiol Young. 2014 Dec 22;:1-4. [Epub ahead of print] PubMed PMID: 25531744
  • Jone PN, Bremen C, DiMaria M, Campbell DN, Jaggers J, Younoszai A, Ivy DD. Three-Dimensional Echocardiography Enhances Diagnostic Accuracy of Supramitral Ring. Echocardiography. 2014 Dec 12. [Epub ahead of print] PubMed PMID: 25496227
  • Di Maria MV, Younoszai AK, Mertens L, Landeck BF 2nd, Ivy DD, Hunter KS, Friedberg MK. RV stroke work in children with pulmonary arterial hypertension: estimation based on invasive haemodynamic assessment and correlation with outcomes. Heart. 2014 Sep;100(17):1342-7. PubMed PMID: 24780910
  • Cox SE, Soka D, Kirkham FJ, Newton CR, Prentice AM, Makani J, Younoszai AK. Tricuspid regurgitant jet velocity and hospitalization in Tanzanian children with sickle cell anemia. Haematologica. 2014 Jan;99(1):e1-4. PubMed PMID: 24425690
  • Jone PN, Hinzman J, Wagner BD, Ivy DD, Younoszai A. Right Ventricular to Left Ventricular Diameter Ratio at End-Systole in Evaluating Outcomes in Children with Pulmonary Hypertension. J Am Soc Echocardiogr. 2013 Dec 7. [Epub ahead of print] PubMed PMID: 24325962
  • Moon TJ, Miyamoto SD, Younoszai AK, Landeck BF. Left ventricular strain and strain rates are decreased in children with normal fractional shortening after exposure to anthracycline chemotherapy. Cardiol Young. 2013 Sep 18;:1-12. [Epub ahead of print] PubMed PMID: 24044518
  • Burkett DA, Wilson N, Mitchell MB, Younoszai AK. Acute ischaemic heart block in hypoplastic left heart syndrome. Cardiol Young. 2014 Dec 22;:1-4. [Epub ahead of print] PubMed PMID: 25531744
  • Moon TJ, Miyamoto SD, Younoszai AK, Landeck BF. Left ventricular strain and strain rates are decreased in children with normal fractional shortening after exposure to anthracycline chemotherapy. Cardiol Young. 2013 Sep 18;:1-12. [Epub ahead of print] PubMed PMID: 24044518
View All (41 Total) View Less

Professional Memberships

  • American Society of Echocardiography, Fellow
  • American College of Cardiology, Fellow
  • American Heart Association (AHA), Member
  • American Academy of Pediatrics (AAP), Fellow

Practice Locations

Children's Hospital Colorado
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Colorado Fetal Care Center
13123 E 16th Ave
Aurora, CO 80045
855-413-3825

Hospital Affiliation
  • Children's Hospital Colorado
Center Affiliations

Specialty Information

Specialties
  • Pediatric Cardiology, Board Certification (2006)
  • Advanced Cardiac Imaging, Specialized Training (2000)
Conditions & Treatments
  • Heart and Circulation
  • Heart and Circulation - Congenital Heart Disease
Clinical Interests
*Congenital heart defects *Diagnosis and management of heart disease in the fetus *Children with only one ventricle and/or a Fontan circulation *Neurocognitive Development in Children with Single Ventricle Physiology

Care Philosophy
Every child should have a chance to "dream big" no matter what their heart looks like on the inside. I specialize in the care of children with severe forms of congenital heart disease - especially those with only one ventricle ("half a heart"). We focus on not only treating heart disease, but promoting wellness both at home and in school so kids can learn in the most appropriate environment. Every child should discover how to take appropriate risks and dream about their future.

Personal Interests
Skiing, Soccer

Volunteer Activities
Round-up River Ranch Camp for Children with Medical Challenges, Surgeons of Hope Missions to Managua, Nicaragua

Public Speaking
Yes
Echocardiography, Fetal Cardiology, Congenital Heart Disease

General Information

Medical Schools:
  • MD, University of Iowa Roy J. and Lucille A. Carver College of Medicine (1994)
Undergraduate Schools:
  • BS, University of Iowa (IA) (1989)
Internships:
  • Nationwide Children's Hospital/Ohio State University Program (1995)
Residency Programs:
  • Nationwide Children's Hospital/Ohio State University Program, Pediatrics (1997)
Fellowships:
  • California Pacific Medical Center/University of California (San Francisco) Program, Pediatric Cardiology (2000)
Languages: English
Department: Pediatrics-Cardiology
;