Alexis Leal, MD
Assistant Professor, Medicine-Medical Oncology

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Medical School:
  • MD, Texas A&M Health Science Center College of Medicine (2011)
Undergraduate School:
  • BS, Texas A&M University (TX) (2005)
Internship:
  • College of Medicine, Mayo Clinic (Rochester) Program (2012)
Residency:
  • College of Medicine, Mayo Clinic (Rochester) Program, Internal Medicine (2014)
Fellowships:
  • College of Medicine, Mayo Clinic (Rochester) Program, Hematology and Oncology (2017)
Languages: English
Department: Medicine-Medical Oncology

Professional Titles

  • Assistant Professor of Medicine

Recognition & Awards

  • Silver Mayo Quality Fellow Certification, Mayo Clinic School of Graduate Medical Education (2016)
  • Bronze Mayo Quality Fellow Certification, Mayo Clinic School of Graduate Medical Education (2012)
  • Doctor of Medicine with Honors, Texas A&M Health Science Center College of Medicine (2011)
  • Alpha Omega Alpha (AOA), Alpha Omega Alpha (AOA) Honor Medical Society (2010)

Teaching

  • Assistant Professor (2017)
    School of Medicine, Medicine
    GI Medical Oncology

Publications

  • Oba A, Wu YHA, Lieu CH, Meguid C, Colborn KL, Beaty L, Al-Musawi MH, Davis SL, Leal AD, Purcell T, King G, Wooten ES, Fujiwara Y, Goodman KA, Schefter T, Karam SD, Gleisner AL, Ahrendt S, Leong S, Messersmith WA, Schulick RD, Del Chiaro M. Outcome of neoadjuvant treatment for pancreatic cancer in elderly patients: comparative, observational cohort study. Br J Surg. 2021 Aug 19;108(8):976-982. PubMed PMID: 34155509
  • Leal AD, Messersmith WA, Lieu CH. Neoadjuvant treatment of localized pancreatic adenocarcinoma. J Gastrointest Oncol. 2021 Oct;12(5):2461-2474. PubMed PMID: 34790407
  • Kastelowitz N, Marsh MD, McCarter M, Meguid RA, Bhardwaj NW, Mitchell JD, Weyant MJ, Scott C, Schefter T, Stumpf P, Leong S, Messersmith W, Lieu C, Leal AD, Davis SL, Purcell WT, Kane M, Wani S, Shah R, Hammad H, Edmundowicz S, Goodman KA. Impact of Radiation Dose on Postoperative Complications in Esophageal and Gastroesophageal Junction Cancers. Front Oncol. 2021;11:614640. PubMed PMID: 33777751
  • Hartman SJ, Bagby SM, Yacob BW, Simmons DM, MacBeth M, Lieu CH, Davis SL, Leal AD, Tentler JJ, Diamond JR, Eckhardt SG, Messersmith WA, Pitts TM. WEE1 Inhibition in Combination With Targeted Agents and Standard Chemotherapy in Preclinical Models of Pancreatic Ductal Adenocarcinoma. Front Oncol. 2021;11:642328. PubMed PMID: 33869031
  • Thomas J, Leal A, Overman MJ. Clinical Development of Immunotherapy for Deficient Mismatch Repair Colorectal Cancer. Clin Colorectal Cancer. 2020 Jun;19(2):73-81. PubMed PMID: 32173280
  • Leal AD, Krishnamurthy A, Head L, Messersmith WA. Antibody drug conjugates under investigation in phase I and phase II clinical trials for gastrointestinal cancer. Expert Opin Investig Drugs. 2018 Nov;27(11):901-916. PubMed PMID: 30359534
  • O'Sullivan CC, Van Houten HK, Sangaralingham LR, Leal AD, Shinde S, Liu H, Ettinger D, Loprinzi CL, Ruddy KJ. Ten-Year Trends in Antiemetic Prescribing in Patients Receiving Highly Emetogenic Chemotherapy. J Natl Compr Canc Netw. 2018 Mar;16(3):294-299. PubMed PMID: 29523668
  • Leal AD, Van Houten H, Sangaralingham L, Freedman RA, Jemal A, Neuman HB, Haddad TC, Mutter RW, Keegan THM, Mougalian SS, Loprinzi CL, Gross CP, Shah N, Ruddy KJ. Breast Cancer Survivorship Care Variations Between Adjuvant Chemotherapy Regimens. Clin Breast Cancer. 2018 Aug;18(4):e513-e520. PubMed PMID: 29054689
  • Leal AD, Allmer C, Maurer MJ, Shanafelt TD, Cerhan JR, Link BK, Thompson CA. Variability of performance status assessment between patients with hematologic malignancies and their physicians. Leuk Lymphoma. 2018 Mar;59(3):695-701. PubMed PMID: 28718335
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Professional Memberships

  • American Society of Clinical Oncology, Member
  • American Association for Cancer Research, Member

Practice Locations

University of Colorado Cancer Center - Anschutz Medical Campus
1665 Aurora Ct
Aurora, CO 80045
720-848-0300

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

UCHealth Anschutz Outpatient Pavilion - Anschutz Medical Campus
1635 Aurora Ct
Aurora, CO 80045
720-848-0000

Hospital Affiliation
  • University of Colorado Hospital
Center Affiliations

Specialty Information

Specialties
  • Medical Oncology, Board Certification (2017)
  • Internal Medicine, Board Certification (2014)
Conditions & Treatments
  • Cancers - Anal Cancer
  • Cancers
  • Cancers - Biliary Cancer
  • Cancers - Colorectal Cancer
  • Cancers - Gastroenterologic Cancer (Colon, Stomach, Esophageal, Liver)
  • Cancers - Pancreatic Cancer
  • Cancers - Chemotherapy
Clinical Interests
My clinical interests are in treating patients with gastrointestinal malignancies, including colorectal cancer, anal cancer, esophageal cancer, gastric cancer, pancreatic cancer, biliary (bile duct) cancers, gallbladder carcinoma, hepatocellular carcinoma and neuroendocrine tumors of the GI tract. I have an interest in developmental therapeutics and clinical trials.

General Information

Medical Schools:
  • MD, Texas A&M Health Science Center College of Medicine (2011)
Undergraduate Schools:
  • BS, Texas A&M University (TX) (2005)
Internships:
  • College of Medicine, Mayo Clinic (Rochester) Program (2012)
Residency Programs:
  • College of Medicine, Mayo Clinic (Rochester) Program, Internal Medicine (2014)
Fellowships:
  • College of Medicine, Mayo Clinic (Rochester) Program, Hematology and Oncology (2017)
Languages: English
Department: Medicine-Medical Oncology
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