Gordon McLennan, MD
Professor, Radiology

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Medical School:
  • MD, Virginia Commonwealth University School of Medicine (1993)
Undergraduate School:
  • BA, Johns Hopkins University (MD) (1988)
Languages: English
Department: Radiology

Professional Titles

  • Vice Chairman for Clinical Research
  • Section Chief

Teaching

  • Professor (2020)
    School of Medicine, Radiology
    My Research focus is on vascular biology related to dialysis access failure & the molecular mechanisms of tumor development & immunotherapy

Publications

  • Mobley D, Kalloo SD, Baskin KM, Koh E, McLennan G, Narayan R, Towbin R, White S, Weintraub JL. Research Priorities for Percutaneous Arteriovenous Fistula Creation in Patients with End-Stage Renal Disease: Proceedings and Recommendations from a Multidisciplinary Research Consensus Panel. J Vasc Interv Radiol. 2021 Aug;32(8):1240.e1-1240.e8. PubMed PMID: 34332723
  • Koirala N, McLennan G. Mathematical Models for Blood Flow Quantification in Dialysis Access Using Angiography: A Comparative Study. Diagnostics (Basel). 2021 Sep 26;11(10). PubMed PMID: 34679469
  • Mobley D, Kalloo SD, Baskin KM, Koh E, McLennan G, Narayan R, Towbin R, White S, Weintraub JL. Research Priorities for Percutaneous Arteriovenous Fistula Creation in Patients with End-Stage Renal Disease: Proceedings and Recommendations from a Multidisciplinary Research Consensus Panel. J Vasc Interv Radiol. 2021 Aug;32(8):1240.e1-1240.e8. PubMed PMID: 34332723
  • Sin D, McLennan G, Rengier F, Haddadin I, Heresi GA, Bartholomew JR, Fink MA, Thompson D, Partovi S. Acute pulmonary embolism multimodality imaging prior to endovascular therapy. Int J Cardiovasc Imaging. 2021 Jan;37(1):343-358. PubMed PMID: 32862293
  • Das D, Koirala N, Li X, Khan N, Dong F, Zhang W, Mulay P, Shrikhande G, Puskas J, Drazba J, McLennan G. Screening of Polymer-Based Drug Delivery Vehicles Targeting Folate Receptors in Triple-Negative Breast Cancer. J Vasc Interv Radiol. 2020 Nov;31(11):1866-1873.e2. PubMed PMID: 33129432
  • Young JL, McLennan G. Thoracic Central Vein Occlusion in the Dialysis Patient: An Interventional Perspective. Adv Chronic Kidney Dis. 2020 May;27(3):236-242. PubMed PMID: 32891308
  • Sin D, McLennan G, Rengier F, Haddadin I, Heresi GA, Bartholomew JR, Fink MA, Thompson D, Partovi S. Acute pulmonary embolism multimodality imaging prior to endovascular therapy. Int J Cardiovasc Imaging. 2020 Aug 30. [Epub ahead of print] PubMed PMID: 32862293
  • Kirksey L, Droz NM, Vacharajani T, McLennan G, Clair DG, Lyden SP. COVID era "essential surgery" dialysis access management considerations. J Vasc Surg. 2020 Dec;72(6):1845-1849. PubMed PMID: 32798572
  • Li X, Haddadin I, McLennan G, Farivar B, Staub D, Beck A, Thompson D, Partovi S. Inferior vena cava filter - comprehensive overview of current indications, techniques, complications and retrieval rates. Vasa. 2020 Oct;49(6):449-462. PubMed PMID: 32660360
  • Mahameed M, Boukeileh S, Obiedat A, Darawshi O, Dipta P, Rimon A, McLennan G, Fassler R, Reichmann D, Karni R, Preisinger C, Wilhelm T, Huber M, Tirosh B. Pharmacological induction of selective endoplasmic reticulum retention as a strategy for cancer therapy. Nat Commun. 2020 Mar 11;11(1):1304. PubMed PMID: 32161259
  • Koirala N, McLennan G. Blood flow quantification in dialysis access using digital subtraction angiography: A retrospective study. Comput Methods Programs Biomed. 2020 Jul;190:105379. PubMed PMID: 32050137
  • Vachharajani TJ, Kirksey L, McLennan G. Endovascular Bypass for Thoracic Vein Occlusion: An Innovative Technique for Hemodialysis Vascular Access. Am J Kidney Dis. 2020 Apr;75(4):468-470. PubMed PMID: 32046863
  • Das D, Fayazzadeh E, Li X, Koirala N, Wadera A, Lang M, Zernic M, Panick C, Nesbitt P, McLennan G. Quiescent hepatic stellate cells induce toxicity and sensitivity to doxorubicin in cancer cells through a caspase-independent cell death pathway: Central role of apoptosis-inducing factor. J Cell Physiol. 2020 Sep;235(9):6167-6182. PubMed PMID: 31975386
  • Koirala N, McLennan G. Percutaneous reinforced osteoplasty for long bone metastases: a feasibility study. Skeletal Radiol. 2020 Mar;49(3):375-382. PubMed PMID: 31377837
  • Koirala N, Das D, Fayazzadeh E, Sen S, McClain A, Puskas JE, Drazba JA, McLennan G. Folic acid conjugated polymeric drug delivery vehicle for targeted cancer detection in hepatocellular carcinoma. J Biomed Mater Res A. 2019 Nov;107(11):2522-2535. PubMed PMID: 31334591
  • Koirala N, Chauhan N, Thompson D, Karimloo Z, Wunderle K, McLennan G. Quantification of Blood Flow in Dialysis Access Using Custom-Acquisition Protocol and Imaging Methods: A Clinical Validation Study. J Vasc Interv Radiol. 2019 Jul;30(7):1062-1068.e2. PubMed PMID: 30928484
  • Partovi S, Reiber JHC, McLennan G. Topical issue: advanced imaging and endovascular treatment in pulmonary artery diseases. Int J Cardiovasc Imaging. 2019 Aug;35(8):1405-1406. PubMed PMID: 31292780
  • Chen JX, Montgomery J, McLennan G, Stavropoulos SW. Endobronchial Forceps-Assisted and Excimer Laser-Assisted Inferior Vena Cava Filter Removal: The Data, Where We Are, and How It Is Done. Tech Vasc Interv Radiol. 2018 Jun;21(2):85-91. PubMed PMID: 29784126
  • Baskin KM, Durack JC, Abu-Elmagd K, Doellman D, Drews BB, Journeycake JM, Kocoshis SA, McLennan G, Rupp SM, Towbin RB, Wasse H, Mermel LA, Toomay SM, Camillus JC, Ahrar K, White SB. Chronic Central Venous Access: From Research Consensus Panel to National Multistakeholder Initiative. J Vasc Interv Radiol. 2018 Apr;29(4):461-469. PubMed PMID: 29456059
  • McDevitt JL, Alian A, Kapoor B, Bennett S, Gill A, Levitin A, Sands M, Narayanan Menon KV, Aucejo FN, Estfan B, Pillai AK, Kalva SP, McLennan G. Single-Center Comparison of Overall Survival and Toxicities in Patients with Infiltrative Hepatocellular Carcinoma Treated with Yttrium-90 Radioembolization or Drug-Eluting Embolic Transarterial Chemoembolization. J Vasc Interv Radiol. 2017 Oct;28(10):1371-1377. PubMed PMID: 28689934
  • Klungboonkrong V, Das D, McLennan G. Molecular Mechanisms and Targets of Therapy for Hepatocellular Carcinoma. J Vasc Interv Radiol. 2017 Jul;28(7):949-955. PubMed PMID: 28416267
  • Boules M, Haskins IN, Farias-Kovac M, Guerron AD, Schechtman D, Samotowka M, O'Rourke CP, McLennan G, Walsh RM, Morris-Stiff G. What is the fate of the cholecystostomy tube following percutaneous cholecystostomy?. Surg Endosc. 2017 Apr;31(4):1707-1712. PubMed PMID: 27519595
  • Murali AR, Romero-Marrero C, Miller C, Aucejo F, Levitin A, Gill A, McLennan G, Karuppasamy K, Zein NN, Lopez R, Menon KV. Predictors of Successful Downstaging of Hepatocellular Carcinoma Outside Milan Criteria. Transplantation. 2016 Nov;100(11):2391-2397. PubMed PMID: 27780187
  • Koirala N, Anvari E, McLennan G. Monitoring and Surveillance of Hemodialysis Access. Semin Intervent Radiol. 2016 Mar;33(1):25-30. PubMed PMID: 27013773
  • McLennan G. Stent and Stent-Graft Use in Arteriovenous Dialysis Access. Semin Intervent Radiol. 2016 Mar;33(1):10-4. PubMed PMID: 27011422
  • Liu F, Bennett S, Arrigain S, Schold J, Heyka R, McLennan G, Navaneethan SD. Patency and Complications of Translumbar Dialysis Catheters. Semin Dial. 2015 Jul-Aug;28(4):E41-7. PubMed PMID: 25800550
  • Ouzaid I, Autorino R, Fatica R, Herts BR, McLennan G, Remer EM, Haber GP. Active surveillance for renal angiomyolipoma: outcomes and factors predictive of delayed intervention. BJU Int. 2014 Sep;114(3):412-7. PubMed PMID: 24325283
  • Srinivas SM, Natarajan N, Kuroiwa J, Gallagher S, Nasr E, Shah SN, DiFilippo FP, Obuchowski N, Bazerbashi B, Yu N, McLennan G. Determination of Radiation Absorbed Dose to Primary Liver Tumors and Normal Liver Tissue Using Post-Radioembolization (90)Y PET. Front Oncol. 2014;4:255. PubMed PMID: 25353006
  • Kapoor BS, Esparaz A, Levitin A, McLennan G, Moon E, Sands M. Nonvascular and portal vein applications of cone-beam computed tomography: current status. Tech Vasc Interv Radiol. 2013 Sep;16(3):150-60. PubMed PMID: 23993077
  • Yu N, Srinivas SM, Difilippo FP, Shrikanthan S, Levitin A, McLennan G, Spain J, Xia P, Wilkinson A. Lung dose calculation with SPECT/CT for ?°Yittrium radioembolization of liver cancer. Int J Radiat Oncol Biol Phys. 2013 Mar 1;85(3):834-9. PubMed PMID: 22871239
  • Faramarzalian A, McLennan G, Bennett SL, Babsky A, Bansal N, Lieber M, Bonnac L, Pankiewicz K, Jayaram HN. Variability of apoptosis and response in N1-S1 rodent hepatomas to benzamide riboside and correlation to early changes in water apparent diffusion coefficient and sodium MR imaging. J Vasc Interv Radiol. 2013 Jun;24(6):894-900. PubMed PMID: 23566523
  • McLennan G, Bennett SL, Ju S, Babsky A, Bansal N, Shorten ML, Levitin S, Bonnac L, Panciewicz KW, Jayaram HN. Tumor response and apoptosis of N1-S1 rodent hepatomas in response to intra-arterial and intravenous benzamide riboside. Cardiovasc Intervent Radiol. 2012 Jun;35(3):645-52. PubMed PMID: 21431971
  • Babsky AM, Ju S, Bennett S, George B, McLennan G, Bansal N. Effect of implantation site and growth of hepatocellular carcinoma on apparent diffusion coefficient of water and sodium MRI. NMR Biomed. 2012 Feb;25(2):312-21. PubMed PMID: 21823182
  • Zhou D, Spain J, Moon E, Mclennan G, Sands MJ, Wang W. Retrospective review of 120 celect inferior vena cava filter retrievals: experience at a single institution. J Vasc Interv Radiol. 2012 Dec;23(12):1557-63. PubMed PMID: 23177101
  • Seth R, Manz RM, Dahan IJ, Nuara MJ, Meltzer NE, McLennan G, Alam DS. Comprehensive analysis of the anterolateral thigh flap vascular anatomy. Arch Facial Plast Surg. 2011 Sep-Oct;13(5):347-54. PubMed PMID: 21502468
  • Siskin GP, Haskal ZJ, McLennan G, Dake MD, Haacke EM, McDonald S, Royal W 3rd, Vedantham S, Hubbard D, Sclafani SJ, Andrews RT, Sauder H. Development of a research agenda for evaluation of interventional therapies for chronic cerebrospinal venous insufficiency: proceedings from a multidisciplinary research consensus panel. J Vasc Interv Radiol. 2011 May;22(5):587-93. PubMed PMID: 21514515
  • Babsky AM, Ju S, George B, Bennett S, Huang M, Jayaram HN, McLennan G, Bansal N. Predicting response to benzamide riboside chemotherapy in hepatocellular carcinoma using apparent diffusion coefficient of water. Anticancer Res. 2011 Jun;31(6):2045-51. PubMed PMID: 21737621
  • Zhu X, Tam MD, Pierce G, McLennan G, Sands MJ, Lieber MS, Wang W. Utility of the Amplatzer Vascular Plug in splenic artery embolization: a comparison study with conventional coil technique. Cardiovasc Intervent Radiol. 2011 Jun;34(3):522-31. PubMed PMID: 20700592
  • Lance C, McLennan G, Obuchowski N, Cheah G, Levitin A, Sands M, Spain J, Srinivas S, Shrikanthan S, Aucejo FN, Kim R, Menon KV. Comparative analysis of the safety and efficacy of transcatheter arterial chemoembolization and yttrium-90 radioembolization in patients with unresectable hepatocellular carcinoma. J Vasc Interv Radiol. 2011 Dec;22(12):1697-705. PubMed PMID: 21983055
  • Haskal ZJ, Trerotola S, Dolmatch B, Schuman E, Altman S, Mietling S, Berman S, McLennan G, Trimmer C, Ross J, Vesely T. Stent graft versus balloon angioplasty for failing dialysis-access grafts. N Engl J Med. 2010 Feb 11;362(6):494-503. PubMed PMID: 20147715
  • Georgiades CS, Rodriguez R, Littrup PJ, Frangakis CE, Leveille R, Ahrar K, Atwell TD, Cadeddu J, Trimmer C, Durack JC, Hammers HJ, Meng MV, Raman S, Solomon SB, Zagoria RJ, McLennan G, Laberge JM, Gervais DA, Kee ST. Development of a research agenda for percutaneous renal tumor ablation: proceedings from a multidisciplinary research consensus panel. J Vasc Interv Radiol. 2010 Dec;21(12):1807-16. PubMed PMID: 21111363
  • Ju S, McLennan G, Bennett SL, Liang Y, Bonnac L, Pankiewicz KW, Jayaram HN. Technical aspects of imaging and transfemoral arterial treatment of N1-S1 tumors in rats: an appropriate model to test the biology and therapeutic response to transarterial treatments of liver cancers. J Vasc Interv Radiol. 2009 Mar;20(3):410-4. PubMed PMID: 19167243
  • de Ryk J, Namati E, Weydert J, Thiesse J, McLennan G. New imaging approaches for understanding lung cancer response to treatment. Clin Pharmacol Ther. 2008 Oct;84(4):517-22. PubMed PMID: 18769370
  • Babs'kyi AM, Ju S, Topper S, Bennett S, Atthe B, McLennan G, Bansal N. [Noninvasive monitoring of the hepatocellular carcinoma growth by the method of 1H and 23Na nuclear magnetic resonance]. Ukr Biokhim Zh (1999). 2008 Jul-Aug;80(4):130-7. PubMed PMID: 19140459
  • Stecker MS, Johnson MS, Ying J, McLennan G, Agarwal DM, Namyslowski J, Ahmad I, Shah H, Butty S, Casciani T. Time to hemostasis after traction removal of tunneled cuffed central venous catheters. J Vasc Interv Radiol. 2007 Oct;18(10):1232-9; quiz 1240. PubMed PMID: 17911513
  • Hendee WR, Banovac F, Carson PL, DeFronzo RA, Eckelman WC, Fullerton GD, Larson SM, McLennan G, Welch MJ. Biomedical imaging research opportunities workshop IV: a white paper. Med Phys. 2007 Feb;34(2):673-9. PubMed PMID: 17388185
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Professional Memberships

  • Society of Interventional Radiology, Fellow
  • Radiological Society of North America, Member
  • American College of Radiology, Member
  • Academy for Radiology Research, Member, Board of Directors

Practice Locations

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

CU Medicine Interventional Radiology - Highlands Ranch Specialty Care Center
1500 Park Central Drive
Highlands Ranch, CO 80129
720-516-3066

Hospital Affiliation
  • UCHealth Highlands Ranch Hospital
  • University of Colorado Hospital

Specialty Information

Specialties
  • Diagnostic, Board Certification
  • Vascular and Interventional Radiology, Board Certification (2002, 2018)
Conditions & Treatments
  • Heart and Circulation - Aneurysms
  • Heart and Circulation
  • Heart and Circulation - Aneurysms
  • Heart and Circulation - Angioplasty
  • Heart and Circulation - Peripheral Artery Disease
  • Heart and Circulation - Vascular Malformations
  • Cancers - Biliary Cancer
  • Cancers
  • Cancers - Colorectal Cancer
  • Cancers - Lung Cancer
  • Cancers - Kidney Cancer
  • Cancers - Pancreatic Cancer
  • Cancers - Anal Cancer
  • Cancers - Gastroenterologic Cancer (Colon, Stomach, Esophageal, Liver)
  • Circulatory System and Blood Vessel Health - Abdominal aortic aneurysm
  • Circulatory System and Blood Vessel Health
  • Circulatory System and Blood Vessel Health - Acute mesenteric ischemia
  • Circulatory System and Blood Vessel Health - Aneurysms
  • Circulatory System and Blood Vessel Health - Angioplasty
  • Circulatory System and Blood Vessel Health - Aortic dissection
  • Circulatory System and Blood Vessel Health - Carotid artery disease
  • Circulatory System and Blood Vessel Health - Chronic mesenteric ischemia
  • Circulatory System and Blood Vessel Health - Chronic mesenteric ischemia
  • Circulatory System and Blood Vessel Health - Claudication
  • Circulatory System and Blood Vessel Health - Critical Limb-threatening ischemia
  • Circulatory System and Blood Vessel Health - Dialysis access
  • Circulatory System and Blood Vessel Health - Limb Salvage
  • Circulatory System and Blood Vessel Health - Lower extremity rest pain
  • Circulatory System and Blood Vessel Health - Peripheral arterial disease (PAD)
  • Circulatory System and Blood Vessel Health - Peripheral Artery Disease
  • Circulatory System and Blood Vessel Health - Renal artery stenosis
  • Circulatory System and Blood Vessel Health - TOS - Thoracic Outlet Syndrome
  • Circulatory System and Blood Vessel Health - Varicose Veins
  • Circulatory System and Blood Vessel Health - Vascular Malformations
  • Circulatory System and Blood Vessel Health - Vascular Surgery
  • Bones, Joints and Muscles - Spine Injuries
  • Bones, Joints and Muscles
  • Bones, Joints and Muscles - Back Pain
  • Kidneys and Urinary System - Prostate Disease
  • Kidneys and Urinary System
  • Men's Health - Prostate Conditions
  • Men's Health
  • Men's Health - Infertility and Reproductive Medicine
  • Women's Health
  • Radiology - Interventional
  • Radiology
  • Hereditary Hemorrhagic Telangiectasia (HHT)
  • Critical Care
  • Lungs and Breathing - Pulmonary Embolism
  • Lungs and Breathing
  • Lungs and Breathing - Pulmonary Hypertension
  • Digestive System
  • Bones, Joints and Muscles - Knee Injuries and Disorders
  • Cancers - Bone Cancer
Clinical Interests
Management of vascular diseases including leg pain, leg ulcers, varicose veins, aneurysms, carotid stenosis, Pulmonary Emboli, Deep vein clots & leg swelling. Cancer Therapy for liver, lung, kidney, pancreas & bone cancers Management of prostate enlargement Management of fibroids & pelvic pain Management of pain related to knee arthritis with embolization

Care Philosophy
Interventional Radiology will provide patients with the best opportunity to get care for complex diseases like cancer, vascular disease, prostate problems,

Personal Interests
I have recently moved from the midwest to Denver having taken the leadership role of Section Chief & Vice Chairman for Clinical research without ever having been in the state. I am very excited to be here & these first few weeks have been exhillarating.

Volunteer Activities
I have dedicated my time to furthering the educational & scientific missions of the Interventional Radiology community. It is a small community but by making research and education a major focus, I have been able to build programs that advance medical care & bring minimally invasive therapies to more people.

Public Speaking
Yes
I have given numerous talks nationally & internationally about the impact of Interventional Radiology on the transformation of modern healthcare. This includes talks related to Cancer therapy, Vascular disease management, management of dialysis access problems, Treatments for broken spines from osteoporosis, and pelvic pain & fibroids in women.

General Information

Medical Schools:
  • MD, Virginia Commonwealth University School of Medicine (1993)
Undergraduate Schools:
  • BA, Johns Hopkins University (MD) (1988)
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Languages: English
Department: Radiology
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